HOTAIR: A key regulator of the Wnt/β-catenin signaling cascade in cancer progression and treatment.

[1]  H. Dureja,et al.  A review of Glycogen Synthase Kinase-3 (GSK3) inhibitors for cancers therapies. , 2023, International journal of biological macromolecules.

[2]  N. Altwaijry,et al.  The complex role of MEG3: An emerging long non-coding RNA in breast cancer. , 2023, Pathology, research and practice.

[3]  Gaurav Gupta,et al.  Uncovering the complex role of interferon-gamma in suppressing type 2 immunity to cancer. , 2023, Cytokine.

[4]  M. Tufail HOTAIR in colorectal cancer: structure, function, and therapeutic potential , 2023, Medical Oncology.

[5]  Gaurav Gupta,et al.  From nature to therapy: Luteolin's potential as an immune system modulator in inflammatory disorders , 2023, Journal of biochemical and molecular toxicology.

[6]  Xixia Zhang,et al.  Crosstalk between Wnt/β-catenin signaling pathway and DNA damage response in cancer: a new direction for overcoming therapy resistance , 2023, Frontiers in pharmacology.

[7]  Gaurav Gupta,et al.  Unveiling the connection: Long-chain non-coding RNAs and critical signaling pathways in breast cancer. , 2023, Pathology, research and practice.

[8]  Sami I. Alzarea,et al.  Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling. , 2023, Pathology, research and practice.

[9]  Gaurav Gupta,et al.  Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis. , 2023, Pathology, research and practice.

[10]  M. Mirzaei,et al.  A thorough understanding of the role of lncRNA in prostate cancer pathogenesis; Current knowledge and future research directions. , 2023, Pathology, research and practice.

[11]  Sami I. Alzarea,et al.  The pyroptotic role of Caspase-3/GSDME signalling pathway among various cancer: A Review. , 2023, International journal of biological macromolecules.

[12]  Imran Kazmi,et al.  Galangin as an inflammatory response modulator: An updated overview and therapeutic potential. , 2023, Chemico-biological interactions.

[13]  Partha Palit,et al.  Enhancement of immune surveillance in breast cancer by targeting hypoxic tumor endothelium: Can it be an immunological switch point? , 2023, Frontiers in Oncology.

[14]  G. Gupta,et al.  Recent Developments in the Study of the Microenvironment of Cancer and Drug Delivery. , 2023, Current drug metabolism.

[15]  Howard Y. Chang,et al.  Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis , 2022, eLife.

[16]  Peng Wang,et al.  Exosomal lncRNA HOTAIR induce macrophages to M2 polarization via PI3K/ p-AKT /AKT pathway and promote EMT and metastasis in laryngeal squamous cell carcinoma , 2022, BMC Cancer.

[17]  Wan-Xi Yang,et al.  Crosstalk Between β-CATENIN-Mediated Cell Adhesion and the WNT Signaling Pathway. , 2022, DNA and cell biology.

[18]  Lixia Xiong,et al.  HOTAIR/miR-203/CAV1 Crosstalk Influences Proliferation, Migration, and Invasion in the Breast Cancer Cell , 2022, International journal of molecular sciences.

[19]  N. Gassler,et al.  Invasion-Associated Reorganization of Laminin 332 in Oral Squamous Cell Carcinomas: The Role of the Laminin γ2 Chain in Tumor Biology, Diagnosis, and Therapy , 2022, Cancers.

[20]  D. Chellappan,et al.  Role of Medicinal plant-derived Nutraceuticals as a potential target for the treatment of breast cancer. , 2022, Journal of food biochemistry.

[21]  Kefeng Wang,et al.  Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance , 2022, Cell Death Discovery.

[22]  E. Nice,et al.  Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA , 2022, Molecular cancer.

[23]  Y. Assaraf,et al.  Long non-coding RNA mediated drug resistance in breast cancer. , 2022, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[24]  Jia Song,et al.  Calpain2 Upregulation Regulates EMT-Mediated Pancreatic Cancer Metastasis via the Wnt/β-Catenin Signaling Pathway , 2022, Frontiers in Medicine.

[25]  T. Pawlik,et al.  Intersectionality in cancer care: A systematic review of current research and future directions , 2022, Psycho-oncology.

[26]  Weichun He,et al.  Emerging Therapeutic Strategies for Attenuating Tubular EMT and Kidney Fibrosis by Targeting Wnt/β-Catenin Signaling , 2022, Frontiers in Pharmacology.

[27]  Yanjie Wei,et al.  A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression , 2021, Molecular Cancer.

[28]  M. Hajjari,et al.  Silencing of HOTAIR Induced Apoptosis in Human Colorectal Cancer Cells through Up-Regulation of Bax and Down-Regulation of Bcl2 , 2021, Jentashapir Journal of Cellular and Molecular Biology.

[29]  Yan Zhang,et al.  Drug discovery efforts toward inhibitors of canonical Wnt/β-catenin signaling pathway in the treatment of cancer: a composition-of-matter review (2010-2020). , 2021, Drug discovery today.

[30]  L. Espinosa,et al.  Accumulation of Paneth Cells in Early Colorectal Adenomas Is Associated with Beta-Catenin Signaling and Poor Patient Prognosis , 2021, Cells.

[31]  Yufeng Huang,et al.  Therapeutic strategies targeting Wnt/β-catenin signaling for colorectal cancer (Review) , 2021, International journal of molecular medicine.

[32]  M. McDonough,et al.  Current Evidence and Directions for Future Research in eHealth Physical Activity Interventions for Adults Affected by Cancer: Systematic Review , 2021, JMIR cancer.

[33]  S. Galande,et al.  Epigenetic Regulation of the Wnt/β-Catenin Signaling Pathway in Cancer , 2021, Frontiers in Genetics.

[34]  Chen-zhou Wu,et al.  Wnt/β-catenin signaling in cancers and targeted therapies , 2021, Signal Transduction and Targeted Therapy.

[35]  R. Castillo-Rodríguez,et al.  Crosstalk of the Wnt/β-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells , 2021, Pharmaceuticals.

[36]  M. Longaker,et al.  The role of Wnt signaling in skin fibrosis , 2021, Medicinal research reviews.

[37]  Ying-yong Zhao,et al.  Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis , 2021, Frontiers in Pharmacology.

[38]  Chunling Liu,et al.  Activation of LncRNA HOTAIR by STAT3 Promotes Gefitinib Resistance and Tumourigenesis by Targeting MicroRNA-216a in NSCLC , 2021 .

[39]  F. Bai,et al.  HOTAIR Facilitates Endocrine Resistance in Breast Cancer Through ESR1/miR-130b-3p Axis: Comprehensive Analysis of mRNA-miRNA-lncRNA Network , 2021, International journal of general medicine.

[40]  Ling Zhou,et al.  Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway , 2021, World journal of gastroenterology.

[41]  Hongqiao Zhang,et al.  Targeting oxidative stress in disease: promise and limitations of antioxidant therapy , 2021, Nature Reviews Drug Discovery.

[42]  D. Andrews,et al.  MYC protein interactors in gene transcription and cancer , 2021, Nature Reviews Cancer.

[43]  Shuling Guo,et al.  HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions , 2021, EMBO reports.

[44]  C. Maher,et al.  Long noncoding RNAs in cancer metastasis , 2021, Nature Reviews Cancer.

[45]  Li-jun Shi,et al.  Silencing of Long Non-Coding RNA HOTAIR Alleviates Epithelial–Mesenchymal Transition in Pancreatic Cancer via the Wnt/β-Catenin Signaling Pathway , 2021, Cancer management and research.

[46]  Xiaorui Luan,et al.  LncRNA-HOTAIR activates autophagy and promotes the imatinib resistance of gastrointestinal stromal tumor cells through a mechanism involving the miR-130a/ATG2B pathway , 2021, Cell Death & Disease.

[47]  Sadique Hussain,et al.  FUNCTIONAL FOODS FOR PREVENTION AND TREATMENT OF CANCER , 2021 .

[48]  Ya Zhang,et al.  Targeting the Wnt/β-catenin signaling pathway in cancer , 2020, Journal of Hematology & Oncology.

[49]  Xian Shen,et al.  Long noncoding RNAs: functions and mechanisms in colon cancer , 2020, Molecular Cancer.

[50]  Fang Zhu,et al.  Upregulation of CCT-3 Induces Breast Cancer Cell Proliferation Through miR-223 Competition and Wnt/β-Catenin Signaling Pathway Activation , 2020, Frontiers in Oncology.

[51]  M. Krampera,et al.  Small Molecule Inhibitors of Microenvironmental Wnt/β-Catenin Signaling Enhance the Chemosensitivity of Acute Myeloid Leukemia , 2020, Cancers.

[52]  Dehua Wu,et al.  HOTAIR expands the population of prostatic cancer stem-like cells and causes Docetaxel resistance via activating STAT3 signaling , 2020, Aging.

[53]  G. Botti,et al.  Long Non-Coding RNA HOTAIR in Breast Cancer Therapy , 2020, Cancers.

[54]  H. Mozdarani,et al.  The emerging role of the long non-coding RNA HOTAIR in breast cancer development and treatment , 2020, Journal of Translational Medicine.

[55]  Bin Guo,et al.  Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer , 2019, International journal of molecular sciences.

[56]  Dong-Dong Miao,et al.  Long‐noncoding RNA HOTAIR inhibits immunologic rejection of mouse leukemia cells through activating the Wnt/β‐catenin signaling pathway in a mouse model of leukemia , 2019, Journal of cellular physiology.

[57]  Meichao Zhang,et al.  NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer , 2019, Oncogene.

[58]  Yunfei Wang,et al.  Long non-coding RNA HOTAIR mediates the switching of histone H3 lysine 27 acetylation to methylation to promote epithelial-to-mesenchymal transition in gastric cancer , 2018, International journal of oncology.

[59]  Zhongbo Zhang,et al.  Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists , 2018, Cancer science.

[60]  Y. Li,et al.  HOTAIR, a long noncoding RNA, is a marker of abnormal cell cycle regulation in lung cancer , 2018, Cancer science.

[61]  F. Guo,et al.  The action mechanism of lncRNA-HOTAIR on the drug resistance of non-small cell lung cancer by regulating Wnt signaling pathway , 2018, Experimental and therapeutic medicine.

[62]  Yang Zhang,et al.  LncRNA HOTAIR is a Prognostic Biomarker for the Proliferation and Chemoresistance of Colorectal Cancer via MiR-203a-3p-Mediated Wnt/ß-Catenin Signaling Pathway , 2018, Cellular Physiology and Biochemistry.

[63]  Ming-jun Sun,et al.  LncRNA HOTAIR influences cell growth, migration, invasion, and apoptosis via the miR‐20a‐5p/HMGA2 axis in breast cancer , 2018, Cancer medicine.

[64]  Jianjun Wang,et al.  Knockdown of long non-coding RNA HOTAIR inhibits cisplatin resistance of gastric cancer cells through inhibiting the PI3K/Akt and Wnt/β-catenin signaling pathways by up-regulating miR-34a. , 2018, International journal of biological macromolecules.

[65]  Zhengyu Zhang,et al.  Crosstalk between long non‐coding RNAs and Wnt/β‐catenin signalling in cancer , 2018, Journal of cellular and molecular medicine.

[66]  Z. Meng,et al.  Knockdown of long non-coding RNA HOTAIR sensitizes hepatocellular carcinoma cell to cisplatin by suppressing the STAT3/ABCB1 signaling pathway. , 2017, Oncology Letters.

[67]  M. Manjili Tumor Dormancy and Relapse: From a Natural Byproduct of Evolution to a Disease State. , 2017, Cancer research.

[68]  Linda Koch Functional genomics: Screening for lncRNA function , 2017, Nature Reviews Genetics.

[69]  Ksenia Myacheva,et al.  Challenges of CRISPR/Cas9 applications for long non-coding RNA genes , 2016, Nucleic acids research.

[70]  M. Boutros,et al.  Wnt signaling in cancer , 2016, Oncogene.

[71]  Jingfeng Liu,et al.  The function of homeobox genes and lncRNAs in cancer. , 2016, Oncology letters.

[72]  Rajat K. De,et al.  Wnt signal transduction pathways: modules, development and evolution , 2016, BMC Systems Biology.

[73]  D-S Li,et al.  Identification of key long non-coding RNAs as competing endogenous RNAs for miRNA-mRNA in lung adenocarcinoma. , 2016, European review for medical and pharmacological sciences.

[74]  Xudong Shi,et al.  A crosstalk between TGF-β/Smad3 and Wnt/β-catenin pathways promotes vascular smooth muscle cell proliferation. , 2016, Cellular Signalling.

[75]  G. Yochum,et al.  Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer. , 2015, World journal of biological chemistry.

[76]  Xin Yu,et al.  Long non-coding RNA HOTAIR: A novel oncogene (Review). , 2015, Molecular medicine reports.

[77]  Jindan Yu,et al.  LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer , 2015, Oncogene.

[78]  E. Zhang,et al.  LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer , 2015, Cell Death and Disease.

[79]  S. Monga β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis. , 2015, Gastroenterology.

[80]  Hui Li,et al.  Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma. , 2015, International journal of oncology.

[81]  Y. Graba,et al.  Cellular and molecular insights into Hox protein action , 2015, Development.

[82]  B. Thisse,et al.  Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway , 2014, Nature Communications.

[83]  J. Rogers,et al.  Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease , 2014, Neuron.

[84]  Hui Li,et al.  Long noncoding RNA HOTAIR involvement in cancer , 2014, Tumor Biology.

[85]  Yin Zheng,et al.  Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells , 2014, Tumor Biology.

[86]  Jin-hua Jiang,et al.  Upregulation of the long noncoding RNA HOTAIR predicts recurrence in stage Ta/T1 bladder cancer , 2014, Tumor Biology.

[87]  K. Hua,et al.  Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer. , 2014, Gynecologic oncology.

[88]  X-W Xie,et al.  Role of HOTAIR long noncoding RNA in metastatic progression of lung cancer. , 2014, European review for medical and pharmacological sciences.

[89]  Jian Chen,et al.  Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer. , 2014, Oncology reports.

[90]  M. Weng,et al.  Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer , 2014, Molecular Cancer.

[91]  A. Bhan,et al.  Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo , 2014, The Journal of Steroid Biochemistry and Molecular Biology.

[92]  Yanchun Liang,et al.  Lentivirus-Mediated RNA Interference Targeting the Long Noncoding RNA HOTAIR Inhibits Proliferation and Invasion of Endometrial Carcinoma Cells In Vitro and In Vivo , 2014, International Journal of Gynecologic Cancer.

[93]  Ryan N Serio Wnt of the two horizons: putting stem cell self-renewal and cell fate determination into context. , 2014, Stem cells and development.

[94]  M. Zheng,et al.  Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer , 2014, Archives of Gynecology and Obstetrics.

[95]  Makoto Nishio,et al.  Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer , 2014, Cancer medicine.

[96]  Haiyang Xie,et al.  Long Non-Coding RNA HOTAIR Promotes Cell Migration and Invasion via Down-Regulation of RNA Binding Motif Protein 38 in Hepatocellular Carcinoma Cells , 2014, International journal of molecular sciences.

[97]  X. Wan,et al.  The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis. , 2014, International journal of molecular medicine.

[98]  W. Hahn,et al.  Genomic insights into WNT/β-catenin signaling. , 2014, Trends in pharmacological sciences.

[99]  J. Chen,et al.  Wnt/β-catenin signaling pathway may regulate the expression of angiogenic growth factors in hepatocellular carcinoma , 2014, Oncology letters.

[100]  Maite Huarte,et al.  Long non-coding RNAs and chromatin modifiers , 2014, Epigenetics.

[101]  Xiao-Hui Zheng,et al.  HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF‐1 expression and activates Wnt pathway , 2013, Cancer science.

[102]  T. Jiang,et al.  HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma. , 2013, Neuro-oncology.

[103]  M. Larsen,et al.  Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer , 2013, Breast Cancer Research and Treatment.

[104]  Lei Jin,et al.  Upregulation of the long non‐coding rna hotair promotes esophageal squamous cell carcinoma metastasis and poor prognosis , 2013, Molecular carcinogenesis.

[105]  N. Tanaka,et al.  Enhanced Expression of Long Non-Coding RNA HOTAIR Is Associated with the Development of Gastric Cancer , 2013, PloS one.

[106]  Jing Liu,et al.  The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer , 2013, BMC Cancer.

[107]  M. Behmanesh,et al.  Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues , 2013, Medical Oncology.

[108]  Ikuro Sato,et al.  Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancer. , 2013, Biochemical and biophysical research communications.

[109]  B. Su,et al.  Long Noncoding RNA HOTAIR Is Associated with Motility, Invasion, and Metastatic Potential of Metastatic Melanoma , 2013, BioMed research international.

[110]  C. Gong,et al.  Long non‐coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival , 2013, Cancer science.

[111]  Jeannie T. Lee,et al.  Long Noncoding RNAs: Past, Present, and Future , 2013, Genetics.

[112]  Chakresh Kumar Jain,et al.  The Wnt pathway: emerging anticancer strategies. , 2013, Recent patents on endocrine, metabolic & immune drug discovery.

[113]  Ethan Lee,et al.  The way Wnt works: Components and mechanism , 2013, Growth factors.

[114]  R. Mehra,et al.  Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. , 2012, Cancer research.

[115]  A. Reis,et al.  Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo , 2012, Oncogene.

[116]  S. Safe,et al.  HOTAIR IS A NEGATIVE PROGNOSTIC FACTOR AND EXHIBITS PRO-ONCOGENIC ACTIVITY IN PANCREATIC CANCER , 2012, Oncogene.

[117]  M. Toyota,et al.  Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. , 2012, Cancer research.

[118]  S. Krauss,et al.  Wnt/beta-Catenin Signaling and Small Molecule Inhibitors , 2012, Current pharmaceutical design.

[119]  I. Schmidt-Wolf,et al.  Understanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia , 2011, Leukemia research and treatment.

[120]  Q. Li,et al.  Large Intervening Non-Coding RNA HOTAIR is Associated with Hepatocellular Carcinoma Progression , 2011, The Journal of international medical research.

[121]  Howard Y. Chang,et al.  Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. , 2011, Molecular cell.

[122]  C. Perret,et al.  The Wnt/β-catenin pathway as a therapeutic target in human hepatocellular carcinoma. , 2011, Clinics and research in hepatology and gastroenterology.

[123]  S. Miyano,et al.  Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. , 2011, Cancer research.

[124]  D. Cacchiarelli,et al.  A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA , 2011, Cell.

[125]  P. Pandolfi,et al.  A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language? , 2011, Cell.

[126]  H. Yao,et al.  Targeting the Wnt/β-catenin signaling pathway in human cancers , 2011, Expert opinion on therapeutic targets.

[127]  M. Kahn,et al.  Wnt/β-catenin Signaling in Embryonic Stem Cell Self-renewal and Somatic Cell Reprogramming , 2011, Stem Cell Reviews and Reports.

[128]  Shiping Liu,et al.  The sequence, structure and evolutionary features of HOTAIR in mammals , 2011, BMC Evolutionary Biology.

[129]  Haiyang Xie,et al.  Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation , 2011, Annals of Surgical Oncology.

[130]  Howard Y. Chang,et al.  HOTAIR: Flight of noncoding RNAs in cancer metastasis , 2010, Cell cycle.

[131]  Yi Zhang,et al.  Role of H3K27 methylation in the regulation of lncRNA expression , 2010, Cell Research.

[132]  Howard Y. Chang,et al.  Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis , 2010, Nature.

[133]  Xi He,et al.  Wnt/beta-catenin signaling: components, mechanisms, and diseases. , 2009, Developmental cell.

[134]  J. Rinn,et al.  Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression , 2009, Proceedings of the National Academy of Sciences.

[135]  D. Spector,et al.  Long noncoding RNAs: functional surprises from the RNA world. , 2009, Genes & development.

[136]  Qian Tao,et al.  Epigenetic disruption of the WNT/ß-catenin signaling pathway in human cancers , 2009, Epigenetics.

[137]  J. Jessen Noncanonical Wnt signaling in tumor progression and metastasis. , 2009, Zebrafish.

[138]  M. Duncan,et al.  Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion. , 2008, Cancer research.

[139]  F. Portillo,et al.  SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells. , 2007, Cancer research.

[140]  G. Srivastava,et al.  The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas , 2007, Laboratory Investigation.

[141]  Howard Y. Chang,et al.  Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs , 2007, Cell.

[142]  D. Srinivasan,et al.  Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells. , 2006, Cancer research.

[143]  S. Baylin,et al.  Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction? , 2006, Nature Reviews Cancer.

[144]  Joseph C. Pearson,et al.  Modulating Hox gene functions during animal body patterning , 2005, Nature Reviews Genetics.

[145]  I. Vetter,et al.  Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation , 2005, The FEBS journal.

[146]  D. Grier,et al.  The pathophysiology of HOX genes and their role in cancer , 2005, The Journal of pathology.

[147]  Hans Clevers,et al.  Caught up in a Wnt storm: Wnt signaling in cancer. , 2003, Biochimica et biophysica acta.

[148]  J. Nathans,et al.  A new secreted protein that binds to Wnt proteins and inhibits their activites , 1999, Nature.

[149]  S. Altschul,et al.  Identification of FAP locus genes from chromosome 5q21. , 1991, Science.

[150]  Sami I. Alzarea,et al.  Recent Developments and Challenges in Molecular-Targeted Therapy of Non-Small-Cell Lung Cancer. , 2023, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

[151]  V. Naidu,et al.  Janus Kinase-Signal Transducer and Activator of Transcription Inhibitors for the Treatment and Management of Cancer. , 2023, Journal of Environmental Pathology And Toxicology.

[152]  Xin Li,et al.  Long non-coding RNA in prostate cancer. , 2022, American journal of clinical and experimental urology.

[153]  B. Illades-Aguiar,et al.  HOTAIR Knockdown Decreased the Activity Wnt/β-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells. , 2019, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

[154]  Yun Xiao,et al.  Aberrant Epigenetic Modifications of Non-coding RNAs in Human Disease. , 2018, Advances in experimental medicine and biology.

[155]  R. Yao,et al.  Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway. , 2018, American journal of translational research.

[156]  Suling Liu,et al.  Noncoding RNAs in Cancer Cell Plasticity. , 2016, Advances in experimental medicine and biology.

[157]  Ming Sun,et al.  Involvement of lncRNA dysregulation in gastric cancer. , 2016, Histology and histopathology.

[158]  Y. Wang,et al.  Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer , 2015, Tumor Biology.

[159]  Li Wang,et al.  Long non-coding RNA HOTAIR in carcinogenesis and metastasis. , 2014, Acta biochimica et biophysica Sinica.

[160]  Ming Liu,et al.  Long intergenic noncoding RNA HOTAIR is overexpressed and regulates PTEN methylation in laryngeal squamous cell carcinoma. , 2013, The American journal of pathology.

[161]  Shanling Liu,et al.  [Expression of long non-coding RNA HOTAIR mRNA in ovarian cancer]. , 2013, Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.

[162]  K. Leslie,et al.  Correlation of MTDH/AEG-1 and HOTAIR Expression with Metastasis and Response to Treatment in Sarcoma Patients. , 2011, Journal of cancer science & therapy.

[163]  B. Strahl,et al.  Protein modifications in transcription elongation. , 2009, Biochimica et biophysica acta.

[164]  K. Takemaru,et al.  An oncogenic hub: beta-catenin as a molecular target for cancer therapeutics. , 2008, Handbook of experimental pharmacology.

[165]  R. Moon,et al.  Beta-catenin-independent Wnt pathways: signals, core proteins, and effectors. , 2008, Methods in molecular biology.

[166]  A. Feinberg,et al.  The epigenetic progenitor origin of human cancer , 2006, Nature Reviews Genetics.