Personality and depression: explanatory models and review of the evidence.

Understanding the association between personality and depression has implications for elucidating etiology and comorbidity, identifying at-risk individuals, and tailoring treatment. We discuss seven major models that have been proposed to explain the relation between personality and depression, and we review key methodological issues, including study design, the heterogeneity of mood disorders, and the assessment of personality. We then selectively review the extensive empirical literature on the role of personality traits in depression in adults and children. Current evidence suggests that depression is linked to traits such as neuroticism/negative emotionality, extraversion/positive emotionality, and conscientiousness. Moreover, personality characteristics appear to contribute to the onset and course of depression through a variety of pathways. Implications for prevention and prediction of treatment response are discussed, as well as specific considerations to guide future research on the relation between personality and depression.

[1]  S. Blatt Levels of object representation in anaclitic and introjective depression. , 1974, The Psychoanalytic study of the child.

[2]  H. Akiskal,et al.  The Relationship of Personality to Affective Disorders: A Critical Review , 1983 .

[3]  G. Klerman,et al.  Assessing personality: effects of the depressive state on trait measurement. , 1983, The American journal of psychiatry.

[4]  M B Keller,et al.  Personality and Depression: Empirical Findings , 1983 .

[5]  R. Hirschfeld,et al.  State and personality in depressed and panic patients. , 1987, The American journal of psychiatry.

[6]  Kagan,et al.  The physiology and psychology of behavioral inhibition in children. , 1987, Child development.

[7]  Marc H. Bornstein,et al.  Social, emotional, and personality development , 1988 .

[8]  W. Iacono,et al.  Neurobehavioral aspects of affective disorders. , 1989, Annual review of psychology.

[9]  M B Keller,et al.  Premorbid personality assessments of first onset of major depression. , 1989, Archives of general psychiatry.

[10]  J Ormel,et al.  A model of stability and change in minor psychiatric symptoms: results from three longitudinal studies. , 1990, Psychological medicine. Monograph supplement.

[11]  D. Klein Depressive personality: reliability, validity, and relation to dysthymia. , 1990, Journal of abnormal psychology.

[12]  P. Lewinsohn,et al.  Are people changed by the experience of having an episode of depression? A further test of the scar hypothesis. , 1990, Journal of abnormal psychology.

[13]  C. Duggan,et al.  Does Personality Predict Long-Term Outcome in Depression? , 1990, British Journal of Psychiatry.

[14]  S. Nolen-Hoeksema Responses to depression and their effects on the duration of depressive episodes. , 1991, Journal of abnormal psychology.

[15]  S. Blatt A Cognitive Morphology of Psychopathology , 1991, The Journal of nervous and mental disease.

[16]  O. Hagnell,et al.  Premorbid personality traits and psychosomatic background factors in depression: the Lundby Study 1957-1972. , 1993, Neuropsychobiology.

[17]  G. A. Miller,et al.  Depressive personality in nonclinical subjects. , 1993, The American journal of psychiatry.

[18]  C. R. Cloninger,et al.  A psychobiological model of temperament and character. , 1993, Archives of general psychiatry.

[19]  M C Neale,et al.  A longitudinal twin study of personality and major depression in women. , 1993, Archives of general psychiatry.

[20]  L. R. Goldberg The structure of phenotypic personality traits. , 1993, The American psychologist.

[21]  J. M. Digman Child personality and temperament: Does the five-factor model embrace both domains. , 1994 .

[22]  P. Lewinsohn,et al.  Are adolescents changed by an episode of major depression? , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[23]  S. Mineka,et al.  Temperament, personality, and the mood and anxiety disorders. , 1994, Journal of abnormal psychology.

[24]  M. Shea,et al.  Impact of perfectionism and need for approval on the brief treatment of depression: the National Institute of Mental Health Treatment of Depression Collaborative Research Program revisited. , 1995, Journal of consulting and clinical psychology.

[25]  D L Newman,et al.  Behavioral observations at age 3 years predict adult psychiatric disorders. Longitudinal evidence from a birth cohort. , 1996, Archives of general psychiatry.

[26]  D. Solomon,et al.  Does major depression result in lasting personality change? , 1996, The American journal of psychiatry.

[27]  D. Klein,et al.  Personality traits in the first degree relatives of outpatients with depressive disorders. , 1996, Journal of affective disorders.

[28]  Peter B. Jones,et al.  Developmental Precursors of Affective Illness in a General Population Birth Cohort , 1997 .

[29]  M. Berger,et al.  Personality in patients with affective disorders and their relatives. , 1998, Journal of affective disorders.

[30]  K. Sher,et al.  The relation between personality and anxiety: findings from a 3-year prospective study. , 1998, Journal of abnormal psychology.

[31]  J. van Os,et al.  Early risk factors and adult person–environment relationships in affective disorder , 1999, Psychological Medicine.

[32]  Lee Anna Clark,et al.  Temperament: A new paradigm for trait psychology. , 1999 .

[33]  D. Klein Depressive personality in the relatives of outpatients with dysthymic disorder and episodic major depressive disorder and normal controls. , 1999, Journal of affective disorders.

[34]  A. Korten,et al.  Predicting anxiety and depression from personality: is there a synergistic effect of neuroticism and extraversion? , 2000, Journal of abnormal psychology.

[35]  J. Kwon,et al.  Three-year follow-up of women with the sole diagnosis of depressive personality disorder: subsequent development of dysthymia and major depression. , 2000, The American journal of psychiatry.

[36]  D. Watson Mood and temperament , 2000 .

[37]  T. Joiner,et al.  Tripartite Model of Depression and Anxiety in Youth Psychiatric Inpatients: Relations With Diagnostic Status and Future Symptoms , 2000, Journal of clinical child psychology.

[38]  S. Nolen-Hoeksema,et al.  The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. , 2000, Journal of abnormal psychology.

[39]  B. Roberts,et al.  The rank-order consistency of personality traits from childhood to old age: a quantitative review of longitudinal studies. , 2000, Psychological bulletin.

[40]  J. Kagan,et al.  A controlled study of behavioral inhibition in children of parents with panic disorder and depression. , 2000, The American journal of psychiatry.

[41]  F. Fruyt,et al.  Cloninger's Psychobiological Model of Temperament and Character and the Five-Factor Model of Personality , 2000 .

[42]  R. Murray,et al.  SES01.01 Developmental precursors of affective illness in a general population birth cohort , 2000, European Psychiatry.

[43]  M. Ashton,et al.  Big five factors and facets and the prediction of behavior. , 2001, Journal of personality and social psychology.

[44]  J Ormel,et al.  The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life. , 2001, The American journal of psychiatry.

[45]  D. Klein,et al.  A construct validation study of the Response Styles Questionnaire Rumination Scale in participants with a recent-onset major depressive episode. , 2001, Psychological assessment.

[46]  J. Walker,et al.  Psychological vulnerabilities in patients with major depression vs panic disorder. , 2001, Behaviour research and therapy.

[47]  I. Gotlib,et al.  Behavioral activation and inhibition systems and the severity and course of depression. , 2002, Journal of abnormal psychology.

[48]  R. Mulder Personality pathology and treatment outcome in major depression: a review. , 2002, The American journal of psychiatry.

[49]  A. Farmer,et al.  Neuroticism, extraversion, life events and depression , 2002, British Journal of Psychiatry.

[50]  F. Smit,et al.  Predictors of first incidence of DSM‐III‐R psychiatric disorders in the general population: findings from the Netherlands Mental Health Survey and Incidence Study , 2002, Acta psychiatrica Scandinavica.

[51]  C. Lonigan,et al.  Relations of positive and negative affectivity to anxiety and depression in children: evidence from a latent variable longitudinal study. , 2003, Journal of consulting and clinical psychology.

[52]  Peter McGuffin,et al.  A sib-pair study of the Temperament and Character Inventory scales in major depression. , 2003, Archives of general psychiatry.

[53]  A. Caspi,et al.  Work experiences and personality development in young adulthood. , 2003, Journal of personality and social psychology.

[54]  R. Krueger,et al.  Personality and psychopathology: working toward the bigger picture. , 2003, Journal of personality disorders.

[55]  S. Huprich Evaluating facet-level predictions and construct validity of depressive personality disorder. , 2003, Journal of personality disorders.

[56]  P. Mclean,et al.  Conscientiousness in Depression: Tendencies, Predictive Utility, and Longitudinal Stability , 1997, Cognitive Therapy and Research.

[57]  B. Roberts,et al.  A longitudinal study of the relationships between conscientiousness and the social-environmental factors and substance-use behaviors that influence health. , 2004, Journal of personality.

[58]  L. McWilliams,et al.  Broad and specific personality dimensions associated with major depression in a nationally representative sample. , 2004, Comprehensive psychiatry.

[59]  K. Kendler,et al.  The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression. , 2004, The American journal of psychiatry.

[60]  B. Compas,et al.  Journal of Clinical Child & Adolescent Psychology Temperament, Stress Reactivity, and Coping: Implications for Depression in Childhood and Adolescence , 2022 .

[61]  J. Ormel,et al.  Vulnerability before, during, and after a major depressive episode: a 3-wave population-based study. , 2004, Archives of general psychiatry.

[62]  B. Lahey Commentary: Role of Temperament in Developmental Models of Psychopathology , 2004, Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53.

[63]  D. Zuroff,et al.  Conceptualizing and measuring personality vulnerability to depression: comment on Coyne and Whiffen (1995). , 2004, Psychological bulletin.

[64]  A. Farmer,et al.  Neuroticism: a non-informative marker of vulnerability to psychopathology , 2004, Social Psychiatry and Psychiatric Epidemiology.

[65]  H. Akiskal,et al.  TEMPS-A: progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire. , 2005, Journal of affective disorders.

[66]  D. Klein,et al.  Temperamental emotionality in preschoolers and parental mood disorders. , 2005, Journal of abnormal psychology.

[67]  Kristian E Markon,et al.  PERSONALITY PROCESSES AND INDIVIDUAL DIFFERENCES Delineating the Structure of Normal and Abnormal Personality: An Integrative Hierarchical Approach , 2004 .

[68]  B. Roberts,et al.  Patterns of continuity: a dynamic model for conceptualizing the stability of individual differences in psychological constructs across the life course. , 2005, Psychological review.

[69]  M. Fava,et al.  Tridimensional Personality Questionnaire Factors in Major Depressive Disorder: Relationship to Anxiety Disorder Comorbidity and Age of Onset , 2005, Psychotherapy and Psychosomatics.

[70]  Mary E Stewart,et al.  High harm avoidance and low self-directedness in euthymic young adults with recurrent, early-onset depression. , 2005, Journal of affective disorders.

[71]  C. R. Cloninger,et al.  Can personality assessment predict future depression? A twelve-month follow-up of 631 subjects. , 2006, Journal of affective disorders.

[72]  D. Puigdemont,et al.  Behavioural Inhibition and Behavioural Activation Systems in current and recovered major depression participants , 2006 .

[73]  Nancy L Pedersen,et al.  Personality and major depression: a Swedish longitudinal, population-based twin study. , 2006, Archives of general psychiatry.

[74]  E. Diener,et al.  Love, work, and changes in extraversion and neuroticism over time. , 2006, Journal of personality and social psychology.

[75]  B. Roberts,et al.  Patterns of mean-level change in personality traits across the life course: a meta-analysis of longitudinal studies. , 2006, Psychological bulletin.

[76]  S. Shankman,et al.  Behavioral activation system deficits predict the six-month course of depression. , 2006, Journal of affective disorders.

[77]  Basic dimensions of temperament in relation to personality and psychopathology. , 2006 .

[78]  Paul De Boeck,et al.  From BIS/BAS to the big five , 2006 .

[79]  R. Bagby,et al.  Assessing and interpreting personality change and continuity in patients treated for major depression. , 2006, Psychological assessment.

[80]  D. Klein,et al.  Ten-year stability of depressive personality disorder in depressed outpatients. , 2006, The American journal of psychiatry.

[81]  D. Klein,et al.  Positive emotionality at age 3 predicts cognitive styles in 7-year-old children , 2006, Development and Psychopathology.

[82]  Temperament, character and personality disorders as predictors of response to interpersonal psychotherapy and cognitive-behavioural therapy for depression. , 2010, The British journal of psychiatry : the journal of mental science.

[83]  P. Delespaul,et al.  Evidence that moment‐to‐moment variation in positive emotions buffer genetic risk for depression: a momentary assessment twin study , 2007, Acta psychiatrica Scandinavica.

[84]  Michael C Neale,et al.  A longitudinal study of personality and major depression in a population-based sample of male twins , 2007, Psychological Medicine.

[85]  Franz J. Neyer,et al.  Relationships matter in personality development: evidence from an 8-year longitudinal study across young adulthood. , 2007, Journal of personality.

[86]  A. Caspi,et al.  The Power of Personality: The Comparative Validity of Personality Traits, Socioeconomic Status, and Cognitive Ability for Predicting Important Life Outcomes , 2007, Perspectives on psychological science : a journal of the Association for Psychological Science.

[87]  R. Kotov,et al.  Personality traits and anxiety symptoms: the multilevel trait predictor model. , 2007, Behaviour research and therapy.

[88]  K. Kendler,et al.  The relationship between depressive personality disorder and major depressive disorder: a population-based twin study. , 2007, The American journal of psychiatry.

[89]  W. Iacono,et al.  Most of the girls are alright, but some aren't: Personality trajectory groups from ages 14 to 24 and some associations with outcomes. , 2007, Journal of personality and social psychology.

[90]  P. Muris,et al.  The Ruminative Response Style in Adolescents: An Examination of Its Specific Link to Symptoms of Depression , 2009, Cognitive Therapy and Research.

[91]  Sidney H Kennedy,et al.  Dimensional personality traits and treatment outcome in patients with major depressive disorder. , 2008, Journal of affective disorders.

[92]  Z. Segal,et al.  Personality and Differential Treatment Response in Major Depression: A Randomized Controlled Trial Comparing Cognitive-Behavioural Therapy and Pharmacotherapy , 2008, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[93]  S. Lyubomirsky,et al.  Rethinking Rumination , 2008, Perspectives on psychological science : a journal of the Association for Psychological Science.

[94]  J. Rosenbaum,et al.  Behavioral inhibition , 2021, Depression and anxiety.

[95]  R. Nusslock,et al.  Behavioral Approach System and Behavioral Inhibition System sensitivities and bipolar spectrum disorders: prospective prediction of bipolar mood episodes. , 2008, Bipolar disorders.

[96]  G. Willemsen,et al.  Life events, anxious depression and personality: a prospective and genetic study , 2008, Psychological Medicine.

[97]  Turhan Canli,et al.  Toward a Neurogenetic Theory of Neuroticism , 2008, Annals of the New York Academy of Sciences.

[98]  Adolescent Emotional Development and the Emergence of Depressive Disorders: Temperament and risk for mood disorders in adolescents , 2008 .

[99]  R. Bagby,et al.  Personality and Depression , 2008, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[100]  Filip Smit,et al.  Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. , 2008, The American journal of psychiatry.

[101]  R. Bagby,et al.  Neuroticism as a mediator of treatment response to SSRIs in major depressive disorder. , 2008, Journal of affective disorders.

[102]  J. Adler,et al.  The role of personality in psychotherapy for anxiety and depression. , 2008, Journal of personality.

[103]  R. Krueger,et al.  Behavioral genetics and personality: A new look at the integration of nature and nurture , 2008 .

[104]  Sheri L. Johnson,et al.  Life events as predictors of mania and depression in bipolar I disorder. , 2008, Journal of abnormal psychology.

[105]  D. Klein,et al.  Increased waking salivary cortisol and depression risk in preschoolers: the role of maternal history of melancholic depression and early child temperament. , 2009, Journal of child psychology and psychiatry, and allied disciplines.

[106]  K. Markon,et al.  Differential relations of depression and social anxiety symptoms to the facets of extraversion/positive emotionality. , 2009, Journal of abnormal psychology.

[107]  Patricia Bijttebier,et al.  Temperament and Risk for Depressive Symptoms in Adolescence: Mediation by Rumination and Moderation by Effortful Control , 2009, Journal of abnormal child psychology.

[108]  B. Hankin,et al.  Mediational Pathways Through Which Positive and Negative Emotionality Contribute to Anhedonic Symptoms of Depression: A Prospective Study of Adolescents , 2009, Journal of abnormal child psychology.

[109]  Timothy A Brown,et al.  A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: implications for assessment and treatment. , 2009, Psychological assessment.

[110]  S. Mineka,et al.  Neuroticism as a common dimension in the internalizing disorders , 2009, Psychological Medicine.

[111]  Lauren M. Bylsma,et al.  Does emotion predict the course of major depressive disorder? A review of prospective studies. , 2009, The British journal of clinical psychology.

[112]  D. Klein,et al.  Exploring depressive personality traits in youth: Origins, correlates, and developmental consequences , 2009, Development and Psychopathology.

[113]  R. Bagby,et al.  A five-factor model description of depressive personality disorder. , 2009, Journal of personality disorders.

[114]  Samet Kose,et al.  Cloninger's temperament and character dimensions of personality in patients with major depressive disorder. , 2009, Comprehensive psychiatry.

[115]  P. Muris,et al.  Relations among behavioral inhibition, Big Five personality factors, and anxiety disorder symptoms in non-clinical children , 2009 .

[116]  D. Watson,et al.  What is being assessed and why it matters: the impact of transient error on trait research. , 2009, Journal of personality and social psychology.

[117]  B. Lahey,et al.  Public health significance of neuroticism. , 2009, The American psychologist.

[118]  R. DeRubeis,et al.  Personality change during depression treatment: a placebo-controlled trial. , 2009, Archives of general psychiatry.

[119]  D. Watson Differentiating the mood and anxiety disorders: a quadripartite model. , 2009, Annual review of clinical psychology.

[120]  R. Rapee,et al.  Neuroticism, Life Events and Negative Thoughts in the Development of Depression in Adolescent Girls , 2009, Journal of abnormal child psychology.

[121]  Erik Schouten,et al.  The influence of emotion-focused rumination and distraction on depressive symptoms in non-clinical youth: a meta-analytic review. , 2009, Clinical psychology review.

[122]  P. Cuijpers,et al.  Prevention of major depression. , 2010, Annual review of clinical psychology.

[123]  F. Schmidt,et al.  Linking "big" personality traits to anxiety, depressive, and substance use disorders: a meta-analysis. , 2010, Psychological bulletin.

[124]  T. McGlashan,et al.  State effects of major depression on the assessment of personality and personality disorder. , 2010, The American journal of psychiatry.

[125]  M. Deković,et al.  Transitioning to adolescence: How changes in child personality and overreactive parenting predict adolescent adjustment problems , 2010, Development and Psychopathology.

[126]  D. Klein,et al.  Temperamental emotionality in preschool-aged children and depressive disorders in parents: associations in a large community sample. , 2010, Journal of abnormal psychology.

[127]  F. Spinath,et al.  Sources of cumulative continuity in personality: a longitudinal multiple-rater twin study. , 2010, Journal of personality and social psychology.

[128]  D. Klein,et al.  Temperamental Positive and Negative Emotionality and Children's Depressive Symptoms: A Longitudinal Prospective Study from Age Three to Age Ten , 2010 .

[129]  M C Neale,et al.  Endophenotype: a conceptual analysis , 2010, Molecular Psychiatry.

[130]  Depressive personality and treatment outcome in major depressive disorder. , 2010, Journal of personality disorders.

[131]  Nestor L. Lopez-Duran,et al.  Prodromal symptoms and atypical affectivity as predictors of major depression in juveniles: implications for prevention. , 2010, Journal of child psychology and psychiatry, and allied disciplines.

[132]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[133]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .