Histomorphological evaluation of wound healing potential of cow urine in goats.

The study was conducted on 48 surgically created wounds in twelve apparently healthy goats of either sex of one and half to two years of age and weighing between 10 to 15 kg body weight. The wounds of group I were treated with cow urine topically, while wounds of group II and III were treated with cow urine topically as well as orally (25 ml freshly collected) and pyrogen free distilled water, respectively. Infiltration of inflammatory cells was more pronounced on 7th day of wound healing in all the groups. These cells in later phase of healing were reduced to minimum. Group II exhibited maximum infiltration, neovascularization and fibroblastic proliferation at different intervals of observations followed by group I and group III. It was concluded that cow urine played an excellent role in healing process of surgical wounds when used orally and synergistic effects are added with topical application in goats.