Computer-integrated finite element modeling of human middle ear

Abstract The objective of this study was to produce an improved finite element (FE) model of the human middle ear and to compare the model with human data. We began with a systematic and accurate geometric modeling technique for reconstructing the middle ear from serial sections of a freshly frozen temporal bone. A geometric model of a human middle ear was constructed in a computer-aided design (CAD) environment with particular attention to geometry and microanatomy. Using the geometric model, a working FE model of the human middle ear was created using previously published material properties of middle ear components. This working FE model was finalized by a cross-calibration technique, comparing its predicted stapes footplate displacements with laser Doppler interferometry measurements from fresh temporal bones. The final FE model was shown to be reasonable in predicting the ossicular mechanics of the human middle ear.

[1]  W. T. Peake,et al.  Input impedance of the cochlea in cat. , 1982, The Journal of the Acoustical Society of America.

[2]  A Lewis,et al.  THE SCIENCE OF SOUND , 1997 .

[3]  H J Rice,et al.  Development of a finite element model of the middle ear. , 1996, Revue de laryngologie - otologie - rhinologie.

[4]  W R Funnell,et al.  Finite-element modeling of the normal and surgically repaired cat middle ear. , 1996, The Journal of the Acoustical Society of America.

[5]  C A Laszlo,et al.  Modeling of the cat eardrum as a thin shell using the finite-element method. , 1978, The Journal of the Acoustical Society of America.

[6]  K Nakamura,et al.  New knowledge about the function of the human middle ear: development of an improved analog model. , 1994, The American journal of otology.

[7]  Sunil Puria,et al.  Human middle-ear sound transfer function and cochlear input impedance , 2001, Hearing Research.

[8]  K B Hüttenbrink,et al.  The mechanics of the middle-ear at static air pressures: the role of the ossicular joints, the function of the middle-ear muscles and the behaviour of stapedial prostheses. , 1988, Acta oto-laryngologica. Supplementum.

[9]  H J Beer,et al.  Modelling of Components of the Human Middle Ear and Simulation of Their Dynamic Behaviour , 1999, Audiology and Neurotology.

[10]  Patrick J. Prendergast,et al.  Vibro-Acoustic Modelling of the Outer and Middle Ear Using the Finite-Element Method , 1999, Audiology and Neurotology.

[11]  D. Lim,et al.  Human tympanic membrane. An ultrastructural observation. , 1970, Acta oto-laryngologica.

[12]  Vijay K. Goel Proceedings of the 1999 Bioengineering Conference, Big Sky, Montana, June 16-20, 1999 , 1999 .

[13]  Takuji Koike,et al.  Modeling of the human middle ear using the finite-element method. , 2002, The Journal of the Acoustical Society of America.

[14]  R. Goode,et al.  Effect of Changes in Mass on Middle Ear Function , 1993, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[15]  H Wada,et al.  Analysis of dynamic behavior of human middle ear using a finite-element method. , 1992, The Journal of the Acoustical Society of America.

[16]  P J Prendergast,et al.  Middle-ear dynamics before and after ossicular replacement. , 2000, Journal of biomechanics.

[17]  C A Laszlo,et al.  A critical review of experimental observations on ear-drum structure and function. , 1982, ORL; journal for oto-rhino-laryngology and its related specialties.

[18]  J. Verheul,et al.  FUNCTION AND MECHANICS OF NORMAL, DISEASED AND RECONSTRUCTED MIDDLE EARS , 2000 .

[19]  Kuang-Hua Chang,et al.  An advanced computer-aided geometric modeling and fabrication method for human middle ear. , 2002, Medical engineering & physics.

[20]  R. Rabbitt,et al.  A fibrous dynamic continuum model of the tympanic membrane. , 1986, The Journal of the Acoustical Society of America.

[21]  K R Williams,et al.  A finite element analysis of the natural frequencies of vibration of the human tympanic membrane. Part I. , 1990, British journal of audiology.

[22]  M. R. Stinson,et al.  The spatial distribution of sound pressure within scaled replicas of the human ear canal. , 1985, The Journal of the Acoustical Society of America.

[23]  W R Funnell,et al.  On the damped frequency response of a finite-element model of the cat eardrum. , 1987, The Journal of the Acoustical Society of America.

[24]  M.S.M.G. Vlaming,et al.  Middle ear mechanics studied by laser doppler interferometry , 1987 .

[25]  George Herrmann,et al.  MECHANICS OF BONE FRACTURE , 1972 .

[26]  S. Khanna,et al.  Tympanic-membrane vibrations in human cadaver ears studied by time-averaged holography. , 1972, The Journal of the Acoustical Society of America.

[27]  T R Oxland,et al.  Biomechanical properties of sterilized human auditory ossicles. , 1999, Journal of biomechanics.

[28]  M. Graham,et al.  Human Tympanic Membrane — Malleus Attachment Preliminary Study , 1978, The Annals of otology, rhinology, and laryngology.

[29]  切替 一郎,et al.  The structure and function of the middle ear , 1960 .

[30]  Rong Z. Gan,et al.  Mass Loading on the Ossicles and Middle Ear Function , 2001, The Annals of otology, rhinology, and laryngology.

[31]  Kuang-Hua Chang,et al.  Three-dimensional Modeling of Middle Ear Biomechanics and Its Applications , 2002, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.