Real‐world safety and effectiveness of cenobamate in patients with focal onset seizures: Outcomes from an Expanded Access Program
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K. Hampel | A. Massot-Tarrús | M. Aguilar-Amat | V. Villanueva | M. D. Castro-Vilanova | F. López-González | A. Gómez-Ibáñez | J. Rodríguez-Uranga | M. Garcés | P. Serrano-Castro | P. Cabezudo-García | X. Rodríguez-Osorio | R. Saíz-Díaz | Vanessa García-Morales | A. Del Villar-Igea | Daniel Santos-Carrasco | Débora Sayas | Gustavo Torres-Gaona | M. Martínez-Ferri | Blanca Mercedes-Alvarez
[1] B. Steinhoff,et al. Failure to use new breakthrough treatments for epilepsy , 2023, Epilepsia.
[2] N. Delanty,et al. Adjunctive cenobamate in highly active and ultra‐refractory focal epilepsy: A “real‐world” retrospective study , 2023, Epilepsia.
[3] C. Bien,et al. A retrospective non‐interventional study evaluating the pharmacokinetic interactions between cenobamate and clobazam , 2023, Epilepsia.
[4] F. Villani,et al. Use of cenobamate for the treatment of focal epilepsy: an Italian expert opinion paper , 2022, Expert review of neurotherapeutics.
[5] A. Schulze-Bonhage,et al. Effects of cenobamate on cognitive performance of epilepsy patients , 2022, Seizure.
[6] C. Kellinghaus,et al. Successful treatment of adult Dravet syndrome patients with cenobamate , 2022, Epilepsia.
[7] J. Stern,et al. Dose Adjustment of Concomitant Antiseizure Medications During Cenobamate Treatment: Expert Opinion Consensus Recommendations , 2022, Neurology and Therapy.
[8] S. Dupont,et al. The burden of epilepsy and unmet need in people with focal seizures , 2022, Brain and behavior.
[9] T. Mayer,et al. Real-World Experience Treating Pediatric Epilepsy Patients With Cenobamate , 2022, Frontiers in Neurology.
[10] B. Steinhoff,et al. Long-term Efficacy and Safety From an Open-Label Extension of Adjunctive Cenobamate in Patients With Uncontrolled Focal Seizures , 2022, Neurology.
[11] S. Kothare,et al. Adjunctive use of cenobamate for pediatric refractory focal-onset epilepsy: A single-center retrospective study , 2022, Epilepsy & Behavior.
[12] A. Williamson,et al. Effectiveness and safety of adjunctive cenobamate for focal seizures in adults with developmental disability treated in clinical practice , 2022, Epilepsy & behavior reports.
[13] B. Steinhoff,et al. Efficacy and safety of adjunctive cenobamate: Post-hoc analysis of study C017 in patients grouped by mechanism of action of concomitant antiseizure medications , 2022, Seizure.
[14] E. Perucca,et al. Cenobamate: A Review of its Pharmacological Properties, Clinical Efficacy and Tolerability Profile in the Treatment of Epilepsy. , 2022, CNS & neurological disorders drug targets.
[15] J. Wheless,et al. Initial Real-World Experience With Cenobamate in Adolescents and Adults: A Single Center Experience. , 2022, Pediatric neurology.
[16] Josemir W Sander,et al. Long‐term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program , 2021, Epilepsia.
[17] M. Sperling,et al. Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open‐label study , 2021, Epilepsia.
[18] M. Sperling,et al. Post hoc analysis of a phase 3, multicenter, open‐label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications , 2021, Epilepsia.
[19] J. Serratosa,et al. Identifying key unmet needs and value drivers in the treatment of focal-onset seizures (FOS) in patients with drug-resistant epilepsy (DRE) in Spain through Multi-Criteria Decision Analysis (MCDA) , 2021, Epilepsy & Behavior.
[20] W. Rosenfeld,et al. Efficacy of adjunctive cenobamate based on number of concomitant antiseizure medications, seizure frequency, and epilepsy duration at baseline: A post-hoc analysis of a randomized clinical study , 2021, Epilepsy Research.
[21] G. Jackson,et al. The costs of epilepsy in Australia , 2020, Neurology.
[22] Steve S. Chung,et al. Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures , 2020, Neurology.
[23] M. Sperling,et al. Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open‐label safety study , 2020, Epilepsia.
[24] B. Steinhoff,et al. Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial , 2019, The Lancet Neurology.
[25] S. Patten,et al. The impact of seizures on epilepsy outcomes: A national, community‐based survey , 2017, Epilepsia.
[26] B. Steinhoff,et al. Randomized controlled antiepileptic drug trials miss almost all patients with ongoing seizures , 2017, Epilepsy & Behavior.
[27] D. Jayne,et al. SUMMARY OF PRODUCT CHARACTERISTICS , 2014 .
[28] R. Duncan. Faculty Opinions recommendation of Quantifying the response to antiepileptic drugs: effect of past treatment history. , 2010 .
[29] J. Cramer,et al. The evolution of antiepileptic drug development and regulation , 2010, Epileptic disorders : international epilepsy journal with videotape.
[30] G. Mathern,et al. Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies , 2009, Epilepsia.
[31] T. Egberts,et al. Clinical relevance of patients with epilepsy included in clinical trials , 2008, Epilepsia.
[32] Y. Schiller,et al. Quantifying the response to antiepileptic drugs , 2008, Neurology.
[33] V. Akila,et al. Information , 2001, The Lancet.