Poro-elastic finite element model to predict the failure progression in a lumbar disc due to cyclic loading

There is a steady and concentrated effort to improve finite element models of the spinal motion segment that can simulate various clinical situations accurately. Recent developments in the area of poro-elastic finite element models including fluid structure interaction with in the disc have made it possible to understand the relationship between disc failure mechanisms and time dependent loading. The development of such a finite element model is presented here and used to predict the failure progression in a lumbar disc due to a physiologically relevant cyclic loading. This will help to understand how repetitive lifting is of importance in the development of back injuries.

[1]  N. Boos,et al.  The Course of Macroscopic Degeneration in the Human Lumbar Intervertebral Disc , 2006, Spine.

[2]  J S Wu,et al.  Clarification of the mechanical behaviour of spinal motion segments through a three-dimensional poroelastic mixed finite element model. , 1996, Medical engineering & physics.

[3]  V C Mow,et al.  Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression. , 1998, Journal of biomechanics.

[4]  G B Andersson,et al.  A model to study the disc degeneration process. , 1994, Spine.

[5]  I. Kingma,et al.  Flow-Related Mechanics of the Intervertebral Disc: The Validity of an In Vitro Model , 2005, Spine.

[6]  J D Troup,et al.  Circadian Variation in Stature and the Effects of Spinal Loading , 1985, Spine.

[7]  A Ratcliffe,et al.  Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition. , 1994, Spine.

[8]  G B Andersson,et al.  The influence of lumbar disc height and cross-sectional area on the mechanical response of the disc to physiologic loading. , 1999, Spine.

[9]  Y. Kim,et al.  Prediction of Peripheral Tears in the Anulus of the Intervertebral Disc , 2000, Spine.

[10]  H. R. Lissner,et al.  Repeated loading tests of the lumbar spine; a preliminary report. , 1958, Surgical forum.

[11]  Van C. Mow,et al.  Is the Nucleus Pulposus a Solid or a Fluid? Mechanical Behaviors of the Nucleus Pulposus of the Human Intervertebral Disc , 1996, Spine.

[12]  T. Keller,et al.  Mechanical behavior of the human lumbar spine. II. Fatigue strength during dynamic compressive loading , 1987, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[13]  Vijay K. Goel,et al.  Impact Response of the Intervertebral Disc in a Finite-Element Model , 2000, Spine.

[14]  T. Brown,et al.  Some mechanical tests on the lumbosacral spine with particular reference to the intervertebral discs; a preliminary report. , 1957, The Journal of bone and joint surgery. American volume.

[15]  T Hansson,et al.  In vivo dynamic stiffness of the porcine lumbar spine exposed to cyclic loading: influence of load and degeneration. , 1998, Journal of spinal disorders.

[16]  V C Mow,et al.  The nonlinear characteristics of soft gels and hydrated connective tissues in ultrafiltration. , 1990, Journal of biomechanics.

[17]  K. Broberg,et al.  Slow deformation of intervertebral discs. , 1993, Journal of biomechanics.

[18]  J. Lotz,et al.  Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study. , 1998, Spine.

[19]  Gunnar B J Andersson,et al.  Modeling changes in intervertebral disc mechanics with degeneration. , 2006, The Journal of bone and joint surgery. American volume.

[20]  Hutton Wc,et al.  Do bending, twisting, and diurnal fluid changes in the disc affect the propensity to prolapse? A viscoelastic finite element model , 1996 .

[21]  Y. K. Liu,et al.  Fatigue Response of Lumbar Intervertebral Joints Under Axial Cyclic Loading , 1983, Spine.

[22]  M Solomonow,et al.  Biomechanics of increased exposure to lumbar injury caused by cyclic loading: Part 1. Loss of reflexive muscular stabilization. , 1999, Spine.

[23]  Gunnar B J Andersson,et al.  Recent Advances in Analytical Modeling of Lumbar Disc Degeneration , 2004, Spine.

[24]  A. Maroudas,et al.  Swelling of the intervertebral disc in vitro. , 1981, Connective tissue research.

[25]  P. Brinckmann,et al.  Interlaminar Shear Stresses and Laminae Separation in a Disc: Finite Element Analysis of the L3‐L4 Motion Segment Subjected to Axial Compressive Loads , 1995, Spine.

[26]  A B Schultz,et al.  Finite element stress analysis of an intervertebral disc. , 1974, Journal of biomechanics.

[27]  W. Marras,et al.  An EMG-assisted model of trunk loading during free-dynamic lifting. , 1995, Journal of biomechanics.

[28]  J. Urban,et al.  Swelling Pressure of the Lumbar Intervertebral Discs: Influence of Age, Spinal Level, Composition, and Degeneration , 1988, Spine.

[29]  Y. K. Liu,et al.  Response of the Ligamentous Lumbar Spine to Cyclic Bending Loads , 1988, Spine.

[30]  V C Mow,et al.  Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging , 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[31]  A. White,et al.  Synopsis: Workshop on Idiopathic Low-Back Pain , 1982, Spine.

[32]  B R Simon,et al.  1985 Volvo Award in Biomechanics: Poroelastic Dynamic Structural Models of Rhesus Spinal Motion Segments , 1985, Spine.