The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia
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A. Ferrando | N. Potter | M. Greaves | P. Kearns | C. Harrison | M. Sanchez-Martin | L. Ermini | F. V. van Delft | I. Titley | A. Ford | R. Gale | V. Weston | M. B. Mansur | C. Furness | M. Pombo-de-Oliveira | S. Jenkinson | Victoria J. Weston
[1] Yong Wang,et al. Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer , 2017, Genome research.
[2] Alex A. Pollen,et al. Single‐cell sequencing maps gene expression to mutational phylogenies in PDGF‐ and EGF‐driven gliomas , 2016, Molecular Systems Biology.
[3] A. Ferrando,et al. The genetics and mechanisms of T cell acute lymphoblastic leukaemia , 2016, Nature Reviews Cancer.
[4] F. Cunningham,et al. The Ensembl Variant Effect Predictor , 2016, bioRxiv.
[5] Robert T. Jones,et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. , 2015, Cancer discovery.
[6] Mel Greaves,et al. Evolutionary determinants of cancer. , 2015, Cancer discovery.
[7] D. Linch,et al. Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial , 2015, Leukemia.
[8] J. Radich,et al. Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia , 2015, Science Translational Medicine.
[9] N. Potter,et al. Genetic and Functional Diversity of Propagating Cells in Glioblastoma , 2014, Stem cell reports.
[10] W. Koh,et al. Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics , 2014, Proceedings of the National Academy of Sciences.
[11] C. Swanton,et al. Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine , 2014, Genome Biology.
[12] Rob Pieters,et al. PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events. , 2014, Blood.
[13] Thomas J. Hudson,et al. Corrigendum: Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia , 2014, Nature.
[14] A. Krešo,et al. Evolution of the cancer stem cell model. , 2014, Cell stem cell.
[15] P. A. Futreal,et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing , 2014, Nature Genetics.
[16] M. Stratton,et al. RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia , 2014, Nature Genetics.
[17] P. Campbell,et al. Single-cell mutational profiling and clonal phylogeny in cancer , 2013, Genome research.
[18] Stein Aerts,et al. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia , 2012, Nature Genetics.
[19] E. Petricoin,et al. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia , 2012, Haematologica.
[20] Richard A Young,et al. Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. , 2012, Cancer cell.
[21] R. Kuiper,et al. The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution , 2012, PLoS genetics.
[22] R. Hassan,et al. Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia , 2012, BMC Cancer.
[23] A. Ferrando,et al. Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia , 2011, Nature Genetics.
[24] M. Greaves,et al. Occurrence of identical NOTCH1 mutation in non-twinned sisters with T-cell acute lymphoblastic leukemia , 2011, Leukemia.
[25] F. Sigaux,et al. Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse , 2011, The Journal of experimental medicine.
[26] K. Anderson,et al. Genetic variegation of clonal architecture and propagating cells in leukaemia , 2011, Nature.
[27] James R. Downing,et al. Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells , 2010, Nature.
[28] M. Muckenthaler,et al. The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function , 2010, Leukemia.
[29] James R. Downing,et al. Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia , 2008, Science.
[30] Andrew P. Weng,et al. Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia , 2004, Science.
[31] J. V. van Dongen,et al. Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes , 1993, The Journal of experimental medicine.
[32] M. Lieber,et al. V(D)J recombination: a functional definition of the joining signals. , 1989 .
[33] D C Linch,et al. Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial , 2013, Leukemia.
[34] J. Barata,et al. Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia , 2010, Leukemia.
[35] J. Salk. Clonal evolution in cancer , 2010 .
[36] L. Kearney,et al. Specialized fluorescence in situ hybridization (FISH) techniques for leukaemia research. , 2009, Methods in molecular biology.