Grating-Based X-ray Phase Imaging Using Multiline X-ray Source

Differential phase-contrast X-ray imaging has been performed in a Talbot–Lau configuration, where a multiline X-ray source was used instead of a combination of a hard-X-ray multiple slit and a normal focus X-ray generator. When the multiple slit is used, a high aspect ratio structure is needed and slit width should be below 10 µm for its function. The fabrication and use of such a multislit can be omitted using the presented configuration. The multiline X-ray source was developed by making grooves on a tungsten rotating anode, which was irradiated by an electron beam to generate X-rays. An array of 10 µm line sources with a pitch of 30 µm was formed and combined with a 4.5 µm pitch phase grating and a 5.3 µm pitch amplitude grating to generate differential phase contrast. With a total exposure time of 40 s, a differential phase image depicting cartilages was obtained.

[1]  W. Talbot Facts relating to optical science , 1836 .

[2]  O. Bunk,et al.  Hard x-ray phase tomography with low-brilliance sources. , 2007, Physical review letters.

[3]  A. W. Lohmann,et al.  An interferometer based on the Talbot effect , 1971 .

[4]  Timm Weitkamp,et al.  X-ray wavefront analysis and optics characterization with a grating interferometer , 2005 .

[5]  Franz Pfeiffer,et al.  High-resolution differential phase contrast imaging using a magnifying projection geometry with a microfocus x-ray source , 2007 .

[6]  A. Momose Recent Advances in X-ray Phase Imaging , 2005 .

[7]  John F. Clauser,et al.  New theoretical and experimental results in fresnel optics with applications to matter-wave and X-ray interferometry , 1992 .

[8]  O. Bunk,et al.  Hard-X-ray dark-field imaging using a grating interferometer. , 2008, Nature materials.

[9]  Sensitivity of X-ray Phase Imaging Based on Talbot Interferometry , 2008 .

[10]  Atsushi Momose,et al.  Phase Tomography by X-ray Talbot Interferometry for Biological Imaging , 2006 .

[11]  Atsushi Momose,et al.  Fabrication of diffraction grating for X-ray Talbot interferometer , 2007 .

[12]  A. Momose,et al.  Phase-contrast radiographs of nonstained rat cerebellar specimen. , 1995, Medical physics.

[13]  E. Lau Beugungserscheinungen an Doppelrastern , 1948 .

[14]  Atsushi Momose,et al.  Demonstration of X-Ray Talbot Interferometry , 2003 .

[15]  O. Bunk,et al.  Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources , 2006 .

[16]  Fabrication of Multiple Slit Using Stacked-Sliced Method for Hard X-ray Talbot–Lau Interferometer , 2008 .

[17]  Atsushi Momose,et al.  Efficiency of capturing a phase image using cone-beam x-ray Talbot interferometry. , 2008, Journal of the Optical Society of America. A, Optics, image science, and vision.

[18]  T Suzuki,et al.  Shearing interferometer using the grating as the beam splitter. , 1971, Applied optics.

[19]  Franz Pfeiffer,et al.  X-ray phase imaging with a grating interferometer. , 2005, Optics express.