Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells

[1]  E. Mullaart,et al.  The removal of UV-induced pyrimidine dimers from DNA of rat skin cells in vitro and in vivo in relation to aging , 1989, Mechanisms of Ageing and Development.

[2]  E. Mullaart,et al.  Genotoxic effects of intragastrically administered benzo[a]pyrene in rat liver and intestinal cells. , 1989, Carcinogenesis.

[3]  E. Mullaart,et al.  Age-related induction and disappearance of carcinogen-DNA-adducts in livers of rats exposed to low levels of 2-acetylaminofluorene. , 1989, Chemico-biological interactions.

[4]  G. P. van der Schans,et al.  Comparison of induction and repair of adducts and of alkali-labile sites in human lymphocytes and granulocytes after exposure to ethylating agents. , 1988, Mutation research.

[5]  E. Mullaart,et al.  Differences in pyrimidine dimer removal between rat skin cells in vitro and in vivo. , 1988, The Journal of investigative dermatology.

[6]  A. Uitterlinden,et al.  A search for DNA alterations in the aging mammalian genome: An experimental strategy , 1987, Mechanisms of Ageing and Development.

[7]  B. Strehler Genetic instability as the primary cause of human aging , 1986, Experimental Gerontology.

[8]  E. Mullaart,et al.  UV-induced DNA excision repair in rat fibroblasts during immortalization and terminal differentiation in vitro. , 1986, Experimental cell research.

[9]  D. Knook,et al.  Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. , 1985, Experimental cell research.

[10]  P. Cerutti Prooxidant states and tumor promotion. , 1985, Science.

[11]  D. Brash,et al.  Longevity-dependent organ-specific accumulation of DNA damage in two closely related murine species , 1984, Mechanisms of Ageing and Development.

[12]  K. Wheeler,et al.  DNA repair kinetics in irradiated undifferentiated and terminally differentiated cells , 1983, Radiation and environmental biophysics.

[13]  F. Yu Preferential binding of aflatoxin B1 to the transcriptionally active regions of rat liver nucleolar chromatin in vivo and in vitro. , 1983, Carcinogenesis.

[14]  F. Becker,et al.  Fluorometric quantitation of single-stranded DNA: a method applicable to the technique of alkaline elution. , 1982, Analytical biochemistry.

[15]  H. Bernstein,et al.  DNA Damage as the Primary Cause of Aging , 1981, The Quarterly Review of Biology.

[16]  D. Knook The Isolated Hepatocyte: A Cellular Model for Aging Studies , 1980, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[17]  R. Cutler,et al.  Absence of significant age-dependent increase of single-stranded DNA extracted from mouse liver nuclei , 1978, Experimental Gerontology.

[18]  T. Ono,et al.  Does the capacity to rejoin radiation-induced DNA breaks decline in senescent mice? , 1978, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[19]  T. Ono,et al.  Comparative studies of DNA size in various tissues of mice during the aging process , 1976, Experimental Gerontology.

[20]  K. Kohn,et al.  Fractionation of DNA from mammalian cells by alkaline elution. , 1976, Biochemistry.

[21]  C. Chetsanga,et al.  Single-stranded regions in DNA of old mice , 1975, Nature.

[22]  R. Nicolosi,et al.  Changes in the structure of rat liver DNA in relation to age. , 1972, Archives of biochemistry and biophysics.

[23]  T. Lindahl,et al.  Rate of depurination of native deoxyribonucleic acid. , 1972, Biochemistry.

[24]  G. Hahn,et al.  Quantitative changes in unscheduled DNA synthesis in rat muscle cells after differentiation. , 1971, Nature: New biology.

[25]  T. Makinodan,et al.  Age-Associated Changes in the DNA of Mouse Tissue , 1971, Science.