The association of the circle of Willis anomaly and risk of stroke in patients with carotid artery disease.

Results In this retrospective study, we analyzed 175 patients who presented at our outpatient stroke clinic between January, 2013 and June, 2015 with either unilateral symptomatic or asymptomatic carotid artery disease, and who had had CT angiography imaging performed. Demographic properties, carotid artery stenosis and the anomaly of the circle of Willis was recorded. Conclusion There was no statistically significant difference in patients with symptomatic and asymptomatic carotid artery disease in terms of the anomaly of the circle of Willis.

[1]  Diana Delgado,et al.  Cerebrovascular Reserve and Stroke Risk in Patients With Carotid Stenosis or Occlusion: A Systematic Review and Meta-Analysis , 2012, Stroke.

[2]  A. Norbash,et al.  Cerebral Collateral Circulation in Carotid Artery Disease , 2009, Current cardiology reviews.

[3]  Y. Chuang,et al.  Anterior Cerebral Artery A1 Segment Hypoplasia May Contribute to A1 Hypoplasia Syndrome , 2007, European Neurology.

[4]  A. Waaijer,et al.  Anatomic Variations in the Circle of Willis in Patients with Symptomatic Carotid Artery Stenosis Assessed with Multidetector Row CT Angiography , 2006, Cerebrovascular Diseases.

[5]  D. Legemate,et al.  Absent Collateral Function of the Circle of Willis as Risk Factor for Ischemic Stroke , 2003, Cerebrovascular Diseases.

[6]  R. Floris,et al.  Hemodynamic modifications in patients with symptomatic unilateral stenosis of the internal carotid artery: evaluation with MR imaging perfusion sequences. , 2002, AJNR. American journal of neuroradiology.

[7]  J. Hendrikse,et al.  Collateral Ability of the Circle of Willis in Patients With Unilateral Internal Carotid Artery Occlusion: Border Zone Infarcts and Clinical Symptoms , 2001, Stroke.

[8]  W. Mali,et al.  Circle of Willis collateral flow investigated by magnetic resonance angiography. , 1999, Stroke.

[9]  Lippincott Williams Wilkins,et al.  Clinical alert: benefit of carotid endarterectomy for patients with high-grade stenosis of the internal carotid artery. National Institute of Neurological Disorders and Stroke Stroke and Trauma Division. North American Symptomatic Carotid Endarterectomy Trial (NASCET) investigators. , 1991, Stroke.

[10]  T. Beasley,et al.  The impact of absent A1 segment on ischemic stroke characteristics and outcomes. , 2015, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[11]  K. Saraç,et al.  Circle of Willis anomalies in stroke patients related with symptomatic carotid artery disease , 2012 .

[12]  P. Rothwell,et al.  Angiographically defined collateral circulation and risk of stroke in patients with severe carotid artery stenosis. North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group. , 2000, Stroke.