ERG Status at the Margin is Associated with Biochemical Recurrence after Radical Prostatectomy with Positive Surgical Margins.

[1]  T. Wiegel,et al.  Re: Timing of Radiotherapy After Radical Prostatectomy (RadicalS-RT): A Randomised, Controlled Phase 3 Trial. , 2021, European urology.

[2]  R. Fisher,et al.  Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial. , 2020, The Lancet Oncology.

[3]  N. Magné,et al.  Adjuvant radiotherapy versus early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial. , 2020, The Lancet. Oncology.

[4]  A. Briganti,et al.  Prognostic Value of Gleason Score at Positive Surgical Margin in Prostate Cancer: A Systematic Review and Meta-analysis. , 2020, Clinical genitourinary cancer.

[5]  M. Rubin,et al.  Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. I. Molecular Biomarkers in Prostate Cancer , 2020, The American journal of surgical pathology.

[6]  D. Parekh,et al.  A Comprehensive Analysis of the Association Between Gleason Score at a Positive Surgical Margin and the Risk of Biochemical Recurrence After Radical Prostatectomy , 2019, The American journal of surgical pathology.

[7]  G. Sauter,et al.  PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort , 2017, Oncotarget.

[8]  Adam P Dicker,et al.  Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model. , 2017, Journal of Clinical Oncology.

[9]  P. Carroll,et al.  Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies , 2016, Prostate Cancer and Prostatic Disease.

[10]  A. Partin,et al.  Importance of Reporting the Gleason Score at the Positive Surgical Margin Site: Analysis of 4,082 Consecutive Radical Prostatectomy Cases. , 2016, The Journal of urology.

[11]  Jennifer R. Rider,et al.  A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer. , 2015, Journal of the National Cancer Institute.

[12]  A. D'Amico,et al.  Which, when and why? Rational use of tissue-based molecular testing in localized prostate cancer , 2015, Prostate Cancer and Prostatic Disease.

[13]  R. Thompson,et al.  Primary Gleason grade 4 at the positive margin is associated with metastasis and death among patients with Gleason 7 prostate cancer undergoing radical prostatectomy. , 2014, European urology.

[14]  Michael W Kattan,et al.  Do margins matter? The influence of positive surgical margins on prostate cancer-specific mortality. , 2014, European urology.

[15]  Jean Sanderson,et al.  Derivation and assessment of risk prediction models using case-cohort data , 2013, BMC Medical Research Methodology.

[16]  P. Scardino,et al.  Prognostic impact of subclassification of radical prostatectomy positive margins by linear extent and Gleason grade. , 2013, The Journal of urology.

[17]  B. Trock,et al.  Impact of surgical margin status on prostate‐cancer‐specific mortality , 2012, BJU international.

[18]  John Cologne,et al.  Conventional case-cohort design and analysis for studies of interaction. , 2012, International journal of epidemiology.

[19]  Jennifer R. Rider,et al.  The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis , 2012, Cancer Epidemiology, Biomarkers & Prevention.

[20]  J. Kench,et al.  High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy , 2012, BJU international.

[21]  J. Epstein,et al.  Characteristics of positive surgical margins in robotic-assisted radical prostatectomy, open retropubic radical prostatectomy, and laparoscopic radical prostatectomy: a comparative histopathologic study from a single academic center. , 2012, Human pathology.

[22]  J. Hicks,et al.  Immunohistochemistry for ERG Expression as a Surrogate for TMPRSS2-ERG Fusion Detection in Prostatic Adenocarcinomas , 2011, The American journal of surgical pathology.

[23]  P. Humphrey,et al.  Ability of linear length of positive margin in radical prostatectomy specimens to predict biochemical recurrence. , 2011, Urology.

[24]  A. Partin,et al.  Tumor grade at margins of resection in radical prostatectomy specimens is an independent predictor of prognosis. , 2010, Urology.

[25]  P. Humphrey,et al.  The Gleason Score of Tumor at the Margin in Radical Prostatectomy is Predictive of Biochemical Recurrence , 2010, The American journal of surgical pathology.

[26]  S. Boorjian,et al.  The impact of positive surgical margins on mortality following radical prostatectomy during the prostate specific antigen era. , 2010, The Journal of urology.

[27]  W. Gerald,et al.  Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer , 2010, British Journal of Cancer.

[28]  J. Trachtenberg,et al.  Impact of positive surgical margins after radical prostatectomy differs by disease risk group. , 2010, The Journal of urology.

[29]  A. Shalhav,et al.  Length of positive surgical margin after radical prostatectomy as a predictor of biochemical recurrence. , 2009, The Journal of urology.

[30]  N. Willich,et al.  Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[31]  E. Messing,et al.  Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. , 2009, The Journal of urology.

[32]  P. Troncoso,et al.  Natural history of biochemical progression after radical prostatectomy based on length of a positive margin. , 2008, Urology.

[33]  W E Barlow,et al.  Analysis of case-cohort designs. , 1999, Journal of clinical epidemiology.

[34]  T M Therneau,et al.  Computing the Cox Model for Case Cohort Designs , 1999, Lifetime data analysis.

[35]  L. J. Wei,et al.  The Robust Inference for the Cox Proportional Hazards Model , 1989 .

[36]  R. L. Prentice,et al.  A case-cohort design for epidemiologic cohort studies and disease prevention trials , 1986 .