Analytical protein a chromatography as a quantitative tool for the screening of methionine oxidation in monoclonal antibodies.
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Hanns-Christian Mahler | Patrick Bulau | U. Grauschopf | Patrick Bulau | Katharina Diepold | Constanze Knoblich | Nadja Alt | Caroline Loew | Constanze Knoblich | Jürgen Fichtl | Katharina Diepold | Pierre Goldbach | Michael Adler | Ulla Grauschopf | P. Goldbach | M. Adler | N. Alt | C. Loew | Hanns-Christian Mahler | Jürgen Fichtl
[1] Gang Huang,et al. Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn , 2009, Protein science : a publication of the Protein Society.
[2] Kent Axelsson,et al. Oxidation of Human Insulin-like Growth Factor I in Formulation Studies: Kinetics of Methionine Oxidation in Aqueous Solution and in Solid State , 1996, Pharmaceutical Research.
[3] Sanchayita Ghose,et al. Antibody variable region interactions with Protein A: implications for the development of generic purification processes. , 2005, Biotechnology and bioengineering.
[4] N. Brot,et al. Biochemistry and physiological role of methionine sulfoxide residues in proteins. , 1983, Archives of biochemistry and biophysics.
[5] M. Mølhøj,et al. Simultaneous Assessment of Asp Isomerization and Asn Deamidation in Recombinant Antibodies by LC-MS following Incubation at Elevated Temperatures , 2012, PloS one.
[6] Hongcheng Liu,et al. Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody. , 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[7] Hongcheng Liu,et al. Effect of methionine oxidation of a recombinant monoclonal antibody on the binding affinity to protein A and protein G. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[8] Kinetics of chemical degradation in monoclonal antibodies: relationship between rates at the molecular and peptide levels. , 2010, Analytical chemistry.
[9] A. Pappenberger,et al. Degradation of polysorbates 20 and 80: studies on thermal autoxidation and hydrolysis. , 2011, Journal of pharmaceutical sciences.
[10] A. Hagman,et al. Oxidation of Human Insulin-Like Growth Factor I in Formulation Studies, II. Effects of Oxygen, Visible Light, and Phosphate on Methionine Oxidation in Aqueous Solution and Evaluation of Possible Mechanisms , 1996, Pharmaceutical Research.
[11] J L Cleland,et al. Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2. , 1997, Journal of pharmaceutical sciences.
[12] P. Johns,et al. Direct determination of methionine sulfoxide in milk proteins by enzyme hydrolysis/high-performance liquid chromatography. , 2007, Journal of chromatography. A.
[13] C. Lowe,et al. Design, synthesis, and application of a Protein A mimetic , 1998, Nature Biotechnology.
[14] L. Björck,et al. Purification and some properties of streptococcal protein G, a novel IgG-binding reagent. , 1984, Journal of immunology.
[15] Y. Shechter,et al. Selective oxidation and reduction of methionine residues in peptides and proteins by oxygen exchange between sulfoxide and sulfide. , 1986, The Journal of biological chemistry.
[16] E. Kabat,et al. Sequences of proteins of immunological interest , 1991 .
[17] B. Frangione,et al. The amino acid sequence of a human immunoglobulin G3m(g) pFc' fragment. , 1977, Journal of immunology.
[18] Ajit S. Narang,et al. Reactive Impurities in Excipients: Profiling, Identification and Mitigation of Drug–Excipient Incompatibility , 2011, AAPS PharmSciTech.
[19] E. Stadtman,et al. Oxidation of methionine residues of proteins: biological consequences. , 2003, Antioxidants & redox signaling.
[20] Andreas Petzold,et al. Identification of Potential Sites for Tryptophan Oxidation in Recombinant Antibodies Using tert-Butylhydroperoxide and Quantitative LC-MS , 2011, PloS one.
[21] J. Goding. Use of staphylococcal protein A as an immunological reagent. , 1978, Journal of immunological methods.
[22] Hanns-Christian Mahler,et al. The Degradation of Polysorbates 20 and 80 and its Potential Impact on the Stability of Biotherapeutics , 2011, Pharmaceutical Research.
[23] G. Kronvall,et al. Definition of staphylococcal protein A reactivity for human immunoglobulin G fragments. , 1970, Immunochemistry.
[24] J. Deisenhofer. Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. , 1981, Biochemistry.
[25] M. Ryadnov,et al. FTIR markers of methionine oxidation for early detection of oxidized protein therapeutics , 2011, European Biophysics Journal.
[26] Yang Wang,et al. Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies. , 2011, Molecular immunology.
[27] G J Kleywegt,et al. Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. , 1995, Structure.
[28] C. Mohan,et al. The Human IgG Subclasses , 2001 .
[29] Y. Burstein,et al. Selective oxidation of methionine residues in proteins. , 1975, Biochemistry.
[30] C. Schöneich. Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease. , 2005, Biochimica et biophysica acta.
[31] J. Sjöquist,et al. Protein a from Staphylococcus aureus. Its isolation by affinity chromatography and its use as an immunosorbent for isolation of immunoglobulins , 1972, FEBS letters.
[32] Hongcheng Liu,et al. Structural effect of deglycosylation and methionine oxidation on a recombinant monoclonal antibody. , 2008, Molecular immunology.
[33] B. Yan,et al. HIC resolution of an IgG1 with an oxidized Trp in a complementarity determining region. , 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.