Penn Medicine Head and Neck Cancer Service Line COVID‐19 management guidelines

The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) virus has altered the health care environment for the management of head and neck cancers. The purpose of these guidelines is to provide direction during the pandemic for rational Head and Neck Cancer management in order to achieve a medically and ethically appropriate balance of risks and benefits.

[1]  A. Chalian,et al.  Tracheotomy in Ventilated Patients With COVID-19 , 2020, Annals of surgery.

[2]  G. Weinstein,et al.  Considerations in the evaluation and management of oral potentially malignant disorders during the COVID‐19 pandemic , 2020, Head & neck.

[3]  J. Palmer,et al.  Aerosol or droplet: critical definitions in the COVID‐19 era , 2020, International forum of allergy & rhinology.

[4]  P. Dulguerov,et al.  Salivary gland disease in the era of COVID‐19 pandemic , 2020, Head & neck.

[5]  John W. Scott,et al.  Protecting Surgical Teams During the COVID-19 Outbreak , 2020, Annals of surgery.

[6]  G. Weinstein,et al.  Topical preparations to reduce SARS‐CoV‐2 aerosolization in head and neck mucosal surgery , 2020, Head & neck.

[7]  R. Cohen,et al.  Care of immunocompromised patients with head and neck cancer during the COVID‐19 pandemic: Two challenging and informative clinical cases , 2020, Head & neck.

[8]  D. Welling,et al.  Endonasal instrumentation and aerosolization risk in the era of COVID‐19: simulation, literature review, and proposed mitigation strategies , 2020, International forum of allergy & rhinology.

[9]  G. Weinstein,et al.  Management of the difficult airway in the COVID‐19 pandemic: Illustrative complex head and neck cancer scenario , 2020, Head & neck.

[10]  S. Lei,et al.  Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection , 2020, EClinicalMedicine.

[11]  S. Inui,et al.  Chest CT Findings in Cases from the Cruise Ship Diamond Princess with Coronavirus Disease (COVID-19) , 2020, Radiology. Cardiothoracic imaging.

[12]  A. Spinelli,et al.  How COVID-19 Outbreak Is Impacting Colorectal Cancer Patients in Italy: A Long Shadow Beyond Infection. , 2020, Diseases of the colon and rectum.

[13]  Dylan H. Morris,et al.  Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 , 2020, The New England journal of medicine.

[14]  Ruiyun Li,et al.  Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2) , 2020, Science.

[15]  J. Rosenberg,et al.  Submental island flap vs free tissue transfer in oral cavity reconstruction: Systematic review and meta‐analysis , 2020, Head & neck.

[16]  John Y. K. Lee,et al.  ICAR: endoscopic skull‐base surgery , 2019, International forum of allergy & rhinology.

[17]  S. Lipsitz,et al.  Evaluating an Intervention to Improve Communication Between Oncology Clinicians and Patients With Life-Limiting Cancer: A Cluster Randomized Clinical Trial of the Serious Illness Care Program. , 2019, JAMA oncology.

[18]  T. Fojo,et al.  Cisplatin versus cetuximab with definitive concurrent radiotherapy for head and neck squamous cell carcinoma: An analysis of Veterans Health Affairs data , 2018, Cancer.

[19]  E. Genden,et al.  Cisplatin Every 3 Weeks Versus Weekly With Definitive Concurrent Radiotherapy for Squamous Cell Carcinoma of the Head and Neck. , 2018, Journal of the National Cancer Institute.

[20]  B. Burkey,et al.  Increased pathologic upstaging with rising time to treatment initiation for head and neck cancer: A mechanism for increased mortality , 2018, Cancer.

[21]  F. Dias,et al.  The role of transoral robotic surgery in the management of oropharyngeal cancer , 2017, Current opinion in oncology.

[22]  D. Flieder,et al.  Survival Impact of Increasing Time to Treatment Initiation for Patients With Head and Neck Cancer in the United States. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  D. Kutler,et al.  Adoption of transoral robotic surgery compared with other surgical modalities for treatment of oropharyngeal squamous cell carcinoma , 2016, Journal of surgical oncology.

[24]  Zhiwei Chen,et al.  Spatiotemporal interplay of severe acute respiratory syndrome coronavirus and respiratory mucosal cells drives viral dissemination in rhesus macaques , 2015, Mucosal Immunology.

[25]  Pablo H. Montero,et al.  Cancer of the oral cavity. , 2015, Surgical oncology clinics of North America.

[26]  D. Flieder,et al.  Increasing time to treatment initiation for head and neck cancer: An analysis of the National Cancer Database , 2015, Cancer.

[27]  Simion I. Chiosea,et al.  Extracapsular spread in head and neck carcinoma: Impact of site and human papillomavirus status , 2013, Cancer.

[28]  D. Kallogjeri,et al.  Extracapsular spread and adjuvant therapy in human papillomavirus‐related, p16‐positive oropharyngeal carcinoma , 2012, Cancer.

[29]  J. Pignon,et al.  Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. , 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[30]  A. Carney,et al.  Organ preservation surgery for laryngeal cancer , 2009, Head & neck oncology.

[31]  A. Garden,et al.  Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[32]  W. Robinson,et al.  Human immunodeficiency virus‐1 (HIV‐1) in the vapors of surgical power instruments , 1991, Journal of medical virology.

[33]  L M Dzubow,et al.  Infectious papillomavirus in the vapor of warts treated with carbon dioxide laser or electrocoagulation: detection and protection. , 1989, Journal of the American Academy of Dermatology.

[34]  P. Rosenberg,et al.  J OURNAL OF C LINICAL O NCOLOGY Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States , 2014 .