Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression.
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[1] R. O'Connor,et al. HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H+ ATPase , 2014, Oncogene.
[2] Jiahuai Han,et al. The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. , 2014, Cell metabolism.
[3] J. Rubinstein,et al. Eukaryotic V-ATPase: novel structural findings and functional insights. , 2014, Biochimica et biophysica acta.
[4] P. Campochiaro,et al. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling , 2014, Autophagy.
[5] K. Webster,et al. Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis , 2013, Oncotarget.
[6] Jaleh Barar,et al. Dysregulated pH in Tumor Microenvironment Checkmates Cancer Therapy. , 2013, BioImpacts : BI.
[7] Dennis Brown,et al. Regulation of luminal acidification by the V-ATPase. , 2013, Physiology.
[8] Xiaofei Li,et al. The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer , 2013, Diagnostic Pathology.
[9] W. Westbroek,et al. Vacuolar H+ ATPase expression and activity is required for Rab27B‐dependent invasive growth and metastasis of breast cancer , 2013, International journal of cancer.
[10] S. Avnet,et al. V-ATPase is a candidate therapeutic target for Ewing sarcoma. , 2013, Biochimica et biophysica acta.
[11] Cory M. Robinson,et al. Interleukin-27 inhibits phagosomal acidification by blocking vacuolar ATPases. , 2013, Cytokine.
[12] Y. Wada,et al. Vacuolar-type proton pump ATPases: acidification and pathological relationships. , 2013, Histology and histopathology.
[13] C. Plass,et al. Genome-wide epigenetic regulation of miRNAs in cancer. , 2013, Cancer research.
[14] T. Taniguchi,et al. MicroRNAs and DNA damage response , 2013, Cell cycle.
[15] A. Vollmar,et al. Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition* , 2012, The Journal of Biological Chemistry.
[16] Xiaoyan Li,et al. V-ATPase promotes transforming growth factor-β-induced epithelial-mesenchymal transition of rat proximal tubular epithelial cells. , 2012, American journal of physiology. Renal physiology.
[17] A. Serrano,et al. Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer. , 2012, Current pharmaceutical design.
[18] S. Sennoune,et al. Vacuolar H(+)-ATPase signaling pathway in cancer. , 2012, Current protein & peptide science.
[19] C. Chung,et al. Enhanced Lysosomal Activity Is Involved in Bax Inhibitor-1-induced Regulation of the Endoplasmic Reticulum (ER) Stress Response and Cell Death against ER Stress , 2011, The Journal of Biological Chemistry.
[20] C. Mader,et al. The vacuolar-ATPase (V-ATPase) modulates matrix metalloproteinase (MMP) isoforms in human pancreatic cancer , 2010, Laboratory Investigation.
[21] Reinhard Dechant,et al. Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V‐ATPase , 2010, The EMBO journal.
[22] T. Schüpbach,et al. The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. , 2009, Developmental cell.
[23] M. Akita,et al. The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma , 2008, Pediatric Surgery International.
[24] M. Futai,et al. The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function , 2008, Current Opinion in Cell Biology.
[25] F. Lozupone,et al. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. , 2004, Journal of the National Cancer Institute.
[26] Shigenori Tamaki,et al. Vacuolar H+-ATPase inhibitor induces apoptosis via lysosomal dysfunction in the human gastric cancer cell line MKN-1. , 2003, Journal of biochemistry.
[27] T. Nishi,et al. The vacuolar (H+)-ATPases — nature's most versatile proton pumps , 2002, Nature Reviews Molecular Cell Biology.
[28] T. Terada,et al. Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan‐1 , 1998, The Journal of pathology.