Sp1 and Sp3 mediate NHE2 gene transcription in the intestinal epithelial cells.
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M. Lipko | F. Ghishan | P. Kiela | P. Hua | Hua Xu | Jia-li Dong | J. Uno
[1] Yanfang Guan,et al. NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[2] S. Dehm,et al. The modification of Sp3 isoforms by SUMOylation has differential effects on the SRC1A promoter. , 2006, Gene.
[3] P. Majumder,et al. Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[4] A. Perkins,et al. Human KLF17 is a new member of the Sp/KLF family of transcription factors. , 2006, Genomics.
[5] V. Yang,et al. Krüppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells , 2006, Nucleic acids research.
[6] R. Urrutia,et al. The family feud: turning off Sp1 by Sp1-like KLF proteins. , 2005, The Biochemical journal.
[7] B. Ogretmen,et al. Sp1/Sp3-dependent Regulation of Human Telomerase Reverse Transcriptase Promoter Activity by the Bioactive Sphingolipid Ceramide* , 2005, Journal of Biological Chemistry.
[8] T. Ferro,et al. Sp1: regulation of gene expression by phosphorylation. , 2005, Gene.
[9] F. Ghishan,et al. Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8. , 2005, American journal of physiology. Gastrointestinal and liver physiology.
[10] S. Simmons,et al. Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. , 2005, Cellular signalling.
[11] M. Inouye,et al. NF1 transcriptional factor(s) is required for basal promoter activation of the human intestinal NaPi-IIb cotransporter gene. , 2005, American journal of physiology. Gastrointestinal and liver physiology.
[12] M. Donowitz,et al. Molecular physiology of intestinal Na+/H+ exchange. , 2005, Annual review of physiology.
[13] O. Fromigué,et al. Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts. , 2005, Experimental cell research.
[14] S. Friedman,et al. Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells , 2004, Oncogene.
[15] Z. Ding,et al. The SANT Domain of Human MI-ER1 Interacts with Sp1 to Interfere with GC Box Recognition and Repress Transcription from Its Own Promoter* , 2004, Journal of Biological Chemistry.
[16] M. Manns,et al. The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[17] L. Huber,et al. Inhibitory Effect of TIS7 on Sp1-C/EBPα Transcription Factor Module Activity☆ , 2004 .
[18] Y. Kawai,et al. Sp Family of Transcription Factors Is Involved in Valproic Acid-induced Expression of Gαi2 * , 2003, The Journal of Biological Chemistry.
[19] M. Inouye,et al. Transcriptional regulation of the human NaPi-IIb cotransporter by EGF in Caco-2 cells involves c-myb. , 2003, American journal of physiology. Cell physiology.
[20] Merlin Crossley,et al. Modification with SUMO , 2003, EMBO reports.
[21] S. Philipsen,et al. Regulation of the activity of Sp1-related transcription factors , 2002, Molecular and Cellular Endocrinology.
[22] G. Shull,et al. Intestinal NaCl transport in NHE2 and NHE3 knockout mice. , 2002, American journal of physiology. Gastrointestinal and liver physiology.
[23] B. van der Burg,et al. The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1* , 2001, The Journal of Biological Chemistry.
[24] J. Collins,et al. Epidermal growth factor regulation of rat NHE2 gene expression. , 2001, American journal of physiology. Cell physiology.
[25] P. Jackers,et al. Fli-1 Inhibits Collagen Type I Production in Dermal Fibroblasts via an Sp1-dependent Pathway* , 2001, The Journal of Biological Chemistry.
[26] H. Ugai,et al. Independent Repression of a GC-rich Housekeeping Gene by Sp1 and MAZ Involves the Same cis-Elements* , 2001, The Journal of Biological Chemistry.
[27] J. Collins,et al. Transcriptional regulation of rat Na(+)/H(+) exchanger isoform-2 (NHE-2) gene by Sp1 transcription factor. , 2001, American journal of physiology. Cell physiology.
[28] E. Chang,et al. IFN-gamma downregulates expression of Na(+)/H(+) exchangers NHE2 and NHE3 in rat intestine and human Caco-2/bbe cells. , 2001, American journal of physiology. Cell physiology.
[29] T. Layden,et al. The human Na(+)/H(+) exchanger NHE2 gene: genomic organization and promoter characterization. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[30] G. Boivin,et al. Variant form of diffuse corporal gastritis in NHE2 knockout mice. , 2000, Comparative medicine.
[31] M. Crossley,et al. Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription. , 2000, Nucleic acids research.
[32] Chow Cw. Regulation and intracellular localization of the epithelial isoforms of the Na+/H+ exchangers NHE2 and NHE3. , 1999 .
[33] J. Collins,et al. Characterization of cis-elements required for osmotic response of rat Na+/H+exchanger-2 ( NHE-2) gene. , 1999, American journal of physiology. Regulatory, integrative and comparative physiology.
[34] G. Suske. The Sp-family of transcription factors. , 1999, Gene.
[35] M. Donowitz,et al. NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation. , 1999, American journal of physiology. Cell physiology.
[36] H. Thai,et al. Effects of AT1 receptor blockade after myocardial infarct on myocardial fibrosis, stiffness, and contractility. , 1999, American journal of physiology. Heart and circulatory physiology.
[37] H. Edenberg,et al. Sp3 and Sp4 Can Repress Transcription by Competing with Sp1 for the Core cis-Elements on the Human ADH5/FDHMinimal Promoter* , 1999, The Journal of Biological Chemistry.
[38] J. Collins,et al. Molecular cloning and characterization of the rat NHE-2 gene promoter. , 1998, Biochimica et biophysica acta.
[39] K. Webster,et al. Hypoxia Regulates β-Enolase and Pyruvate Kinase-M Promoters by Modulating Sp1/Sp3 Binding to a Conserved GC Element* , 1998, The Journal of Biological Chemistry.
[40] E. Chang,et al. Regulation of apical membrane Na+/H+exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe. , 1998, American journal of physiology. Cell physiology.
[41] L. Aiello,et al. Transcription Factors Sp1 and Sp3 Alter Vascular Endothelial Growth Factor Receptor Expression through a Novel Recognition Sequence* , 1998, The Journal of Biological Chemistry.
[42] G. Boivin,et al. Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. , 1998, The Journal of clinical investigation.
[43] J. Collins,et al. Functional and molecular characterization of NHE3 expression during ontogeny in rat jejunal epithelium. , 1997, American journal of physiology. Cell physiology.
[44] Barbara Majello,et al. Sp3 Is a Bifunctional Transcription Regulator with Modular Independent Activation and Repression Domains* , 1997, The Journal of Biological Chemistry.
[45] M. Donowitz,et al. Hyperosmolarity inhibits the Na+/H+ exchanger isoforms NHE2 and NHE3: an effect opposite to that on NHE1. , 1996, The American journal of physiology.
[46] G. Stein,et al. Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. , 1995, Biochemistry.
[47] M. Beato,et al. Functional Analyses of the Transcription Factor Sp4 Reveal Properties Distinct from Sp1 and Sp3 (*) , 1995, The Journal of Biological Chemistry.
[48] S. Brant,et al. Mammalian Na+/H+ exchanger gene family: structure and function studies. , 1995, The American journal of physiology.
[49] R. Tjian,et al. Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif , 1988, Cell.
[50] J. Blay,et al. Characterization of an epithelioid cell line derived from rat small intestine: demonstration of cytokeratin filaments. , 1984, Cell biology international reports.
[51] R. Tjian,et al. Multiple specific contacts between a mammalian transcription factor and its cognate promoters , 1984, Nature.
[52] R. Tjian,et al. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter , 1983, Cell.