Acute delusional parasitosis under treatment with ciprofloxacin.

Ciprofloxacin-induced psychoses have been described in some case reports, occurring sometimes in multi-morbid or personality disordered patients, but also in healthy subjects. We present a case of a 45-year-old man without previous mental disorder, who developed an acute delusional parasitosis after administration of ciprofloxacin. After discontinuation of ciprofloxacin, a complete and sustained remission could be observed within a few days, without the use of any psychopharmacologic medication. Possible modes of action are discussed.