Cortical spreading depression transiently activates MAP kinases.

[1]  H. Ueno,et al.  Requirement of Ras for the Activation of Mitogen-Activated Protein Kinase by Calcium Influx, cAMP, and Neurotrophin in Hippocampal Neurons , 2001, The Journal of Neuroscience.

[2]  M. Rudnicki,et al.  Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation. , 2001, Molecular cell.

[3]  M. Linial,et al.  Involvement of extracellular signal-regulated kinase (ERK) in pardaxin-induced dopamine release from PC12 cells. , 2001, The Journal of pharmacology and experimental therapeutics.

[4]  Karl Deisseroth,et al.  Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology , 2001, Nature Neuroscience.

[5]  A. K. Chow,et al.  Preconditioning with Cortical Spreading Depression Decreases Intraischemic Cerebral Glutamate Levels and Down‐Regulates Excitatory Amino Acid Transporters EAAT1 and EAAT2 from Rat Cerebal Cortex Plasma Membranes , 2000, Journal of neurochemistry.

[6]  Z. Gu,et al.  Diphosphorylation of extracellular signal-regulated kinases and c-Jun N-terminal protein kinases in brain ischemic tolerance in rat , 2000, Brain Research.

[7]  R. Kalb,et al.  Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[8]  A. Gundlach,et al.  Prolonged Induction of Neuronal NOS Expression and Activity Following Cortical Spreading Depression (SD): Implications for SD- and NO-Mediated Neuroprotection , 1999, Experimental Neurology.

[9]  M. Moskowitz,et al.  MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[10]  P. Chan,et al.  Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-d-aspartate receptors and glucocorticoids , 1999, Neuroscience.

[11]  M. Shamloo,et al.  Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning , 1999, Neuroscience.

[12]  Yizheng Wang,et al.  Evidence from cultured rat cortical neurons of differences in the mechanism of ischemic preconditioning of brain and heart , 1999, Brain Research.

[13]  A. Brunet,et al.  Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry , 1999, The EMBO journal.

[14]  G. Mies,et al.  Expression of c-fos, junB, c-jun, MKP-1 AND hsp72 following traumatic neocortical lesions in rats—relation to spreading depression , 1999, Neuroscience.

[15]  M. Besson,et al.  Glutamate Induces Phosphorylation of Elk-1 and CREB, Along with c-fos Activation, via an Extracellular Signal-Regulated Kinase-Dependent Pathway in Brain Slices , 1999, Molecular and Cellular Biology.

[16]  Y. Dudai,et al.  Specific and Differential Activation of Mitogen-Activated Protein Kinase Cascades by Unfamiliar Taste in the Insular Cortex of the Behaving Rat , 1998, The Journal of Neuroscience.

[17]  M. Besson,et al.  Extracellular Signal-Regulated Kinase (ERK) Controls Immediate Early Gene Induction on Corticostriatal Stimulation , 1998, The Journal of Neuroscience.

[18]  Andreas Bergmann,et al.  The Drosophila Gene hid Is a Direct Molecular Target of Ras-Dependent Survival Signaling , 1998, Cell.

[19]  R. Schmidt-Kastner,et al.  Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia , 1998, Brain Research.

[20]  E. Furshpan,et al.  Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[21]  R. David Andrew,et al.  Imaging Spreading Depression and Associated Intracellular Calcium Waves in Brain Slices , 1998, The Journal of Neuroscience.

[22]  L. Greene,et al.  Prevention of PC12 Cell Death by N-Acetylcysteine Requires Activation of the Ras Pathway , 1998, The Journal of Neuroscience.

[23]  M. Shamloo,et al.  Sublethal in vitro glucose—oxygen deprivation protects cultured hippocampal neurons against a subsequent severe insult , 1998, Neuroreport.

[24]  F. Wiegand,et al.  Induction of tolerance in rat cortical neurons: hypoxic preconditioning , 1997, FEBS letters.

[25]  H. Rubinfeld,et al.  Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[26]  D. Leroith,et al.  Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways* , 1997, The Journal of Biological Chemistry.

[27]  R. Busto,et al.  Bilateral ischemic tolerance of rat hippocampus induced by prior unilateral transient focal ischemia: relationship to c‐fos mRNA expression , 1996, Neuroreport.

[28]  N. Maulik,et al.  Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts , 1996, FEBS letters.

[29]  Michael E. Greenberg,et al.  Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase , 1996, Science.

[30]  A. Hakim,et al.  Relationship between Extracellular Glutamate Concentration and Voltage-Sensitive Calcium Channel Function in Focal Cerebral Ischemia in the Rat , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[31]  P. Greengard,et al.  Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[32]  A. Hakim,et al.  Cortical Spreading Depression Protects against Subsequent Focal Cerebral Ischemia in Rats , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  Michael E. Greenberg,et al.  Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.

[34]  S. Kobayashi,et al.  Journal of Cerebral Blood Flow and Metabolism Spreading Depression Induces Tolerance of Cortical Neurons to Ischemia in Rat Brain , 2022 .

[35]  A. Hakim,et al.  Transient forebrain ischemia protects against subsequent focal cerebral ischemia without changing cerebral perfusion. , 1995, Stroke.

[36]  D. Graham,et al.  Induction of Ischemic Tolerance following Brief Focal Ischemia in Rat Brain , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[37]  M. Greenberg,et al.  Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras , 1994, Neuron.

[38]  M. Taneda,et al.  Prostaglandin E1 Induces c-Fos and Myc Proteins and Protects Rat Hippocampal Cells against Hypoxic Injury , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[39]  G. Mies,et al.  Correlation between peri-infarct DC shifts and ischaemic neuronal damage in rat. , 1993, Neuroreport.

[40]  Martin Lauritzen,et al.  Microdialysis of interstitial amino acids during spreading depression and anoxic depolarization in rat neocortex , 1993, Brain Research.

[41]  F Benfenati,et al.  Synaptic vesicle phosphoproteins and regulation of synaptic function. , 1993, Science.

[42]  D. G. Herrera,et al.  Application of potassium chloride to the brain surface induces the c-fos proto-oncogene: reversal by MK-801 , 1990, Brain Research.

[43]  Maiken Nedergaard,et al.  Spreading depression is not associated with neuronal injury in the normal brain , 1988, Brain Research.

[44]  Lingzhi Fan,et al.  The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system , 1988, Neuroscience Letters.

[45]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[46]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.