A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.
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Stefan Abele | E. Corley | A. Roy | S. Krska | D. Steinhuebel | M. Weisel | P. O'shea | C. Molinaro | R. Angelaud | S. Shultz | M. Cameron | T. Trinh | S. Lau | Jacques-Alexis Funel