Lysosomes: fusion and function

[1]  J. Luzio,et al.  The Role of Intraorganellar Ca2+In Late Endosome–Lysosome Heterotypic Fusion and in the Reformation of Lysosomes from Hybrid Organelles , 2000, The Journal of cell biology.

[2]  T. Kirchhausen,et al.  An emergency response team for membrane repair , 2005, Nature Reviews Molecular Cell Biology.

[3]  S. Munro,et al.  Organelle identity and the signposts for membrane traffic , 2005, Nature.

[4]  H. Geuze,et al.  Late endosomes derive from early endosomes by maturation , 1991, Cell.

[5]  D. Katzmann,et al.  Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway. , 2006, Molecular biology of the cell.

[6]  B. Winchester,et al.  Lysosomal metabolism of glycoproteins. , 2005, Glycobiology.

[7]  R. D. Fisher,et al.  Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release , 2006, Journal of Virology.

[8]  S. Emr,et al.  New component of ESCRT-I regulates endosomal sorting complex assembly , 2006, The Journal of cell biology.

[9]  T. Galli,et al.  Role of Tetanus Neurotoxin Insensitive Vesicle-Associated Membrane Protein (Ti-Vamp) in Vesicular Transport Mediating Neurite Outgrowth , 2000, The Journal of cell biology.

[10]  Jacques Neefjes,et al.  The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors , 2001, Current Biology.

[11]  M. Maki,et al.  CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway. , 2006, The Biochemical journal.

[12]  J. Luzio,et al.  The role of mVps18p in clustering, fusion, and intracellular localization of late endocytic organelles. , 2003, Molecular biology of the cell.

[13]  R. Scheller,et al.  Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins , 2004, The Journal of cell biology.

[14]  V. Deretic,et al.  Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages , 2004, Cell.

[15]  P. Lehner,et al.  Degradation of Endocytosed Epidermal Growth Factor and Virally Ubiquitinated Major Histocompatibility Complex Class I Is Independent of Mammalian ESCRTII* , 2006, Journal of Biological Chemistry.

[16]  T. Stegmann,et al.  Fusion of Human Neutrophil Phagosomes with Lysosomes in Vitro , 2001, The Journal of Biological Chemistry.

[17]  J. Swanson,et al.  Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles , 2006, Cellular microbiology.

[18]  Xuejun Jiang,et al.  Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. , 2006, Molecular cell.

[19]  S. Hamada,et al.  Autophagy Defends Cells Against Invading Group A Streptococcus , 2004, Science.

[20]  M. Desjardins,et al.  Biogenesis of phagolysosomes: the 'kiss and run' hypothesis. , 1995, Trends in cell biology.

[21]  G. Kroemer,et al.  The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death , 2005, Journal of Cell Science.

[22]  P. Stahl,et al.  Fusion of newly formed phagosomes with endosomes in intact cells and in a cell-free system. , 1991, The Journal of biological chemistry.

[23]  P. Webster,et al.  Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial Cells , 1997, The Journal of cell biology.

[24]  S. Grinstein,et al.  Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP , 2003, Molecular and Cellular Biology.

[25]  S. Grinstein,et al.  Syntaxins 13 and 7 Function at Distinct Steps During Phagocytosis1 , 2002, The Journal of Immunology.

[26]  Daniel J Klionsky,et al.  Development by self-digestion: molecular mechanisms and biological functions of autophagy. , 2004, Developmental cell.

[27]  C. Huynh,et al.  Identification of SNAREs Involved in Synaptotagmin VII-regulated Lysosomal Exocytosis* , 2004, Journal of Biological Chemistry.

[28]  J. Garin,et al.  Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum. , 2002, The Biochemical journal.

[29]  S. Fuller,et al.  Centrosome polarization delivers secretory granules to the immunological synapse , 2006, Nature.

[30]  Barbara J. Reaves,et al.  Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles. , 1997, Journal of cell science.

[31]  Steven M. Becker,et al.  Ca2+ and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes , 2006, The Journal of cell biology.

[32]  W. P. Briggs Foundation for the future. , 1955, The Merck report.

[33]  T. Galli,et al.  Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[34]  J. Luzio,et al.  Membrane dynamics and the biogenesis of lysosomes (Review) , 2003 .

[35]  J. Rohrer,et al.  Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules , 2005, Journal of Cell Science.

[36]  H. Geuze,et al.  Cooperation of GGAs and AP-1 in Packaging MPRs at the Trans-Golgi Network , 2002, Science.

[37]  T. Stevens,et al.  The Saccharomyces cerevisiae v-SNARE Vti1p is required for multiple membrane transport pathways to the vacuole. , 1999, Molecular biology of the cell.

[38]  Juan S. Bonifacino,et al.  Human Vam6p promotes lysosome clustering and fusion in vivo , 2001, The Journal of cell biology.

[39]  B. Deurs,et al.  A Key to Lysosome Biogenesis , 2000 .

[40]  B. Deurs,et al.  Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes. , 1995, European journal of cell biology.

[41]  Viviane Poupon,et al.  Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. , 2003, Molecular biology of the cell.

[42]  J. Hurley,et al.  Molecular Architecture and Functional Model of the Complete Yeast ESCRT-I Heterotetramer , 2007, Cell.

[43]  A. Brech,et al.  A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body. , 2006, Experimental cell research.

[44]  Hiroshi Sagara,et al.  Escape of Intracellular Shigella from Autophagy , 2005, Science.

[45]  D. Klionsky,et al.  Yeast homotypic vacuole fusion requires the Ccz1–Mon1 complex during the tethering/docking stage , 2003, The Journal of cell biology.

[46]  P. Webster,et al.  Cytoplasmic bacteria can be targets for autophagy , 2003, Cellular microbiology.

[47]  D. James,et al.  Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events , 2004, EMBO reports.

[48]  Jean Gruenberg,et al.  Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest , 2001, The Journal of cell biology.

[49]  O. Ullrich,et al.  In Vitro Fusion of Phagosomes with Different Endocytic Organelles from J774 Macrophages* , 1998, The Journal of Biological Chemistry.

[50]  C. Sasakawa,et al.  Intracellular survival of Shigella , 2006, Cellular microbiology.

[51]  CIBA foundation for the Promotion of International Cooperation in Medical and Chemical Research. , 1950, Indian medical journal.

[52]  K. Kirkegaard,et al.  Cellular autophagy: surrender, avoidance and subversion by microorganisms , 2004, Nature Reviews Microbiology.

[53]  Y. Kalaidzidis,et al.  Rab Conversion as a Mechanism of Progression from Early to Late Endosomes , 2005, Cell.

[54]  S. Slaugenhaupt,et al.  Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[55]  P. Walther,et al.  Fusion between phagosomes, early and late endosomes: a role for actin in fusion between late, but not early endocytic organelles. , 2003, Molecular biology of the cell.

[56]  Pier Paolo Di Fiore,et al.  Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation , 2003, Nature Cell Biology.

[57]  B. Wainer,et al.  BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. , 2006, Molecular biology of the cell.

[58]  C. Duve The lysosome turns fifty , 2005, Nature Cell Biology.

[59]  Vojo Deretic,et al.  Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca2+/Calmodulin-PI3K hVPS34 Cascade , 2003, The Journal of experimental medicine.

[60]  H. Stenmark,et al.  Endosomal and non-endosomal functions of ESCRT proteins. , 2006, Trends in cell biology.

[61]  P. Saftig,et al.  Role for Rab7 in maturation of late autophagic vacuoles , 2004, Journal of Cell Science.

[62]  J. Belisle,et al.  Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[63]  M. Scott,et al.  Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events. , 2001, Molecular biology of the cell.

[64]  J. Jaiswal,et al.  Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis , 2004, PLoS biology.

[65]  G. Griffiths,et al.  Cytoplasmic dynein-dependent vesicular transport from early to late endosomes [published erratum appears in J Cell Biol 1994 Feb;124(3):397] , 1993, The Journal of cell biology.

[66]  M. Lindsay,et al.  Localization of phosphatidylinositol 3‐phosphate in yeast and mammalian cells , 2000, The EMBO journal.

[67]  Larissa A. Jarzylo,et al.  Differential requirements for actin polymerization, calmodulin, and Ca2+ define distinct stages of lysosome/phagosome targeting. , 2006, Molecular biology of the cell.

[68]  M. Seaman Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer , 2004, The Journal of cell biology.

[69]  Jean Gruenberg,et al.  The biogenesis of multivesicular endosomes , 2004, Nature Reviews Molecular Cell Biology.

[70]  F. Gu,et al.  Biogenesis of transport intermediates in the endocytic pathway , 1999, FEBS letters.

[71]  Yuki Moriya,et al.  Extracting Sequence Motifs and the Phylogenetic Features of SNARE‐Dependent Membrane Traffic , 2006, Traffic.

[72]  J. Luzio,et al.  Reconstitution of an endosome-lysosome interaction in a cell-free system , 1989, The Journal of cell biology.

[73]  J. Luzio,et al.  Endocytic Delivery to Lysosomes Mediated by Concurrent Fusion and Kissing Events in Living Cells , 2005, Current Biology.

[74]  I. Mellman Endocytosis and molecular sorting. , 1996, Annual review of cell and developmental biology.

[75]  J. Luzio,et al.  Differential Use of Two AP‐3‐mediated Pathways by Lysosomal Membrane Proteins , 2004, Traffic.

[76]  Emma J. Blott,et al.  Secretory lysosomes , 2002, Nature Reviews Molecular Cell Biology.

[77]  D. Rotin,et al.  Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination , 2006, The Journal of cell biology.

[78]  K. Kim,et al.  The K1 capsule modulates trafficking of E. coli‐containing vacuoles and enhances intracellular bacterial survival in human brain microvascular endothelial cells , 2003, Cellular microbiology.

[79]  S. Grinstein,et al.  Salmonella redirects phagosomal maturation. , 2004, Current opinion in microbiology.

[80]  W. Antonin,et al.  A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function , 2000, The EMBO journal.

[81]  M. Wenk,et al.  Salmonella Modulates Vesicular Traffic by Altering Phosphoinositide Metabolism , 2004, Science.

[82]  D. Klionsky,et al.  The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways* , 2002, The Journal of Biological Chemistry.

[83]  R. Arantes,et al.  A Role for Synaptotagmin VII-Regulated Exocytosis of Lysosomes in Neurite Outgrowth from Primary Sympathetic Neurons , 2006, The Journal of Neuroscience.

[84]  W. Antonin,et al.  Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs , 2002, Nature Structural Biology.

[85]  G. Lukács,et al.  The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. , 2006, Molecular biology of the cell.

[86]  R F Murphy,et al.  Maturation models for endosome and lysosome biogenesis. , 1991, Trends in cell biology.

[87]  C. Futter,et al.  Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes , 1996, The Journal of cell biology.

[88]  J. Luzio,et al.  Fusion of Lysosomes with Late Endosomes Produces a Hybrid Organelle of Intermediate Density and Is NSF Dependent , 1998, The Journal of cell biology.

[89]  C. Sasakawa,et al.  Bacterial evasion of the autophagic defense system. , 2006, Current opinion in microbiology.

[90]  Chiara Sabatti,et al.  Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3 , 2005, Journal of Cell Science.

[91]  M. D'Esposito,et al.  A dual mechanism controlling the localization and function of exocytic v-SNAREs , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[92]  P. Cossart,et al.  Listeria monocytogenes: a multifaceted model , 2006, Nature Reviews Microbiology.

[93]  Andrew A. Peden,et al.  A genomic perspective on membrane compartment organization , 2001, Nature.

[94]  S. Grinstein,et al.  A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium , 2007, The Journal of cell biology.

[95]  J. Bonifacino,et al.  The molecular machinery for lysosome biogenesis * , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.

[96]  J. Falcón-Pérez,et al.  BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. , 2006, Molecular biology of the cell.

[97]  I. Jordens,et al.  A splice variant of RILP induces lysosomal clustering independent of dynein recruitment. , 2006, Biochemical and biophysical research communications.

[98]  S. Grinstein,et al.  LAMP proteins are required for fusion of lysosomes with phagosomes , 2007, The EMBO journal.

[99]  C. Arighi,et al.  Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor , 2004, The Journal of cell biology.

[100]  G. Griffiths On vesicles and membrane compartments , 1996, Protoplasma.

[101]  Benedikt Westermann,et al.  SNAREpins: Minimal Machinery for Membrane Fusion , 1998, Cell.

[102]  C. Futter,et al.  The kinetics of mannose 6-phosphate receptor trafficking in the endocytic pathway in HEp-2 cells: the receptor enters and rapidly leaves multivesicular endosomes without accumulating in a prelysosomal compartment. , 1998, Molecular biology of the cell.

[103]  S. Emr,et al.  A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. , 1997, Molecular biology of the cell.

[104]  F. Reimann,et al.  Mucolipin‐1 Is a Lysosomal Membrane Protein Required for Intracellular Lactosylceramide Traffic , 2006, Traffic.

[105]  V. Deretic,et al.  Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism , 2006, Cellular microbiology.

[106]  W. Wickner,et al.  Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lumen , 2004, The Journal of cell biology.

[107]  D. Rubinsztein,et al.  The roles of intracellular protein-degradation pathways in neurodegeneration , 2006, Nature.

[108]  J. Swanson,et al.  Cytolysin‐dependent delay of vacuole maturation in macrophages infected with Listeria monocytogenes , 2006, Cellular microbiology.

[109]  Scott D Emr,et al.  The ESCRT complexes: structure and mechanism of a membrane-trafficking network. , 2006, Annual review of biophysics and biomolecular structure.

[110]  J. Luzio,et al.  Lysosome-endosome fusion and lysosome biogenesis. , 2000, Journal of cell science.

[111]  Nektarios Tavernarakis,et al.  Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans , 2006, The Journal of cell biology.

[112]  Pascale Fung,et al.  Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation , 1989, Infection and immunity.

[113]  C. Futter,et al.  EGF stimulates annexin 1‐dependent inward vesiculation in a multivesicular endosome subpopulation , 2006, The EMBO journal.

[114]  S. Grinstein,et al.  Quantitative and Dynamic Assessment of the Contribution of the ER to Phagosome Formation , 2005, Cell.

[115]  W. Hong,et al.  Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. , 2006, Molecular biology of the cell.

[116]  H. Kita,et al.  A critical role for vesicle‐associated membrane protein‐7 in exocytosis from human eosinophils and neutrophils , 2006, Allergy.

[117]  Markus Babst,et al.  Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. , 2006, Molecular biology of the cell.

[118]  D. Toomre,et al.  Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane , 2002, Nature.

[119]  J. Luzio,et al.  Membrane dynamics and the biogenesis of lysosomes. , 2003, Molecular membrane biology.

[120]  B. Storrie,et al.  The biogenesis of lysosomes: Is it a kiss and run, continuous fusion and fission process? , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[121]  S. Kornfeld,et al.  Mannose 6-phosphate receptors: new twists in the tale , 2003, Nature Reviews Molecular Cell Biology.

[122]  I Mellman,et al.  Acidification of the endocytic and exocytic pathways. , 1986, Annual review of biochemistry.

[123]  N. Andrews,et al.  The Trypanosoma cruzi–host-cell interplay: location, invasion, retention , 2005, Nature Reviews Microbiology.

[124]  P. Roché Faculty Opinions recommendation of Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. , 2006 .

[125]  S. Emr,et al.  A Multispecificity Syntaxin Homologue, Vam3p, Essential for Autophagic and Biosynthetic Protein Transport to the Vacuole , 1997, The Journal of cell biology.

[126]  J. Bonifacino The GGA proteins: adaptors on the move , 2004, Nature Reviews Molecular Cell Biology.

[127]  B. Deurs,et al.  Rab7: a key to lysosome biogenesis. , 2000, Molecular biology of the cell.

[128]  J. Pevsner,et al.  Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. , 2000, Molecular biology of the cell.

[129]  T. Stevens,et al.  Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae. , 2005, Biochimica et biophysica acta.

[130]  A. Brech,et al.  Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes. , 2003, The Biochemical journal.

[131]  Reinhard Jahn,et al.  SNAREs — engines for membrane fusion , 2006, Nature Reviews Molecular Cell Biology.

[132]  R. Puertollano,et al.  Two Di-Leucine Motifs Regulate Trafficking of Mucolipin-1 to Lysosomes , 2006, Traffic.

[133]  F. Gisou van der Goot,et al.  Mechanisms of pathogen entry through the endosomal compartments , 2006, Nature Reviews Molecular Cell Biology.