Optical excitation and detection of vapor bubbles around plasmonic nanoparticles.

Laser-induced generation of the vapor bubbles in water around plasmonic nanoparticles was experimentally studied with optical scattering methods. Nanoparticle-generated bubbles temporally and spatially localize laser-induced thermal field and also amplify optical scattering relatively to that of gold nanoparticles. Bubble lifetimes and threshold fluencies were determined as functions of the laser (pulse duration, fluence, inter-pulse interval), nanoparticle (size, shape, aggregation state) and sample chamber parameters so to optimize bubble generation around plasmonic nanoparticles. Nanoparticle-generated bubbles are suggested as nano-scaled optical sensors and sources of localized thermal and mechanical impact.

[1]  Ralf Brinkmann,et al.  Boiling nucleation on melanosomes and microbeads transiently heated by nanosecond and microsecond laser pulses. , 2005, Journal of biomedical optics.

[2]  A. Vogel,et al.  Mechanisms of femtosecond laser nanosurgery of cells and tissues , 2005 .

[3]  G. Hartland,et al.  Photothermal Properties of Gold Nanoparticles , 2007 .

[4]  Charles P. Lin,et al.  Photomechanical effects: experimental studies of pigment granule absorption, cavitation, and cell damage , 2000, Laser Damage.

[5]  P. Jain,et al.  Au nanoparticles target cancer , 2007 .

[6]  V. Orlovich,et al.  Low-threshold cavitation in water using IR laser pulse trains. , 2008, Applied optics.

[7]  A. Tam Overview Of Photothermal Spectroscopy , 1990, LEOS '90. Conference Proceedings IEEE Lasers and Electro-Optics Society 1990 Annual Meeting.

[8]  E. Faraggi,et al.  Biophysical effects of pulsed lasers in the retina and other tissues containing strongly absorbing particles: shockwave and explosive bubble generation. , 2005, Journal of biomedical optics.

[9]  J. Yguerabide,et al.  Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications. , 1998, Analytical biochemistry.

[10]  K W Ferrara,et al.  Optical and acoustical dynamics of microbubble contrast agents inside neutrophils. , 2001, Biophysical journal.

[11]  Gregory V. Hartland,et al.  Heat Dissipation for Au Particles in Aqueous Solution: Relaxation Time versus Size , 2002 .

[12]  J. Yguerabide,et al.  Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications. , 1998, Analytical biochemistry.

[13]  G. Kastis,et al.  Time‐resolved observations of shock waves and cavitation bubbles generated by femtosecond laser pulses in corneal tissue and water , 1996, Lasers in surgery and medicine.

[14]  Ji-Xin Cheng,et al.  Gold Nanorods Mediate Tumor Cell Death by Compromising Membrane Integrity , 2007, Advanced materials.

[15]  Bernhard Lamprecht,et al.  Spectroscopy of single metallic nanoparticles using total internal reflection microscopy , 2000 .

[16]  Olgert Lindau,et al.  Bubble dynamics, shock waves and sonoluminescence , 1999, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[17]  U S Sathyam,et al.  Threshold and ablation efficiency studies of microsecond ablation of gelatin under water , 1996, Lasers in surgery and medicine.

[18]  Günther Paltauf,et al.  Photomechanical processes and effects in ablation. , 2003, Chemical reviews.

[19]  Brahim Lounis,et al.  Photothermal Imaging of Nanometer-Sized Metal Particles Among Scatterers , 2002, Science.

[20]  M. Mostafavi,et al.  Optical limitation induced by gold clusters: Mechanism and efficiency , 2001 .

[21]  Prashant K. Jain,et al.  Plasmonic photothermal therapy (PPTT) using gold nanoparticles , 2008, Lasers in Medical Science.

[22]  M. El-Sayed,et al.  Shape and size dependence of radiative, non-radiative and photothermal properties of gold nanocrystals , 2000 .

[23]  Warren C W Chan,et al.  Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. , 2007, Nano letters.

[24]  L. Rayleigh VIII. On the pressure developed in a liquid during the collapse of a spherical cavity , 1917 .

[25]  K. Sokolowski-Tinten,et al.  Femtosecond x-ray measurement of ultrafast melting and large acoustic transients. , 2001, Physical review letters.

[26]  Omid C. Farokhzad,et al.  Nanoparticle-Aptamer Bioconjugates , 2004, Cancer Research.

[27]  Constantinos Pitris,et al.  Optical imaging of the cervix , 2003, Cancer.

[28]  Vasan Venugopalan,et al.  Pulsed laser microbeam-induced cell lysis: time-resolved imaging and analysis of hydrodynamic effects. , 2006, Biophysical journal.

[29]  E. Mazur,et al.  Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds. , 2002, Optics express.

[30]  Eric Mazur,et al.  Laser-induced breakdown and damage in bulk transparent materials induced by tightly focused femtosecond laser pulses , 2001 .

[31]  Wolfgang J Parak,et al.  Laser-induced release of encapsulated materials inside living cells. , 2006, Angewandte Chemie.

[32]  M. Wulff,et al.  Time-resolved X-ray diffraction on laser-excited metal nanoparticles , 2003 .

[33]  G. Diebold,et al.  Laser-initiated chemical reactions in carbon suspensions. , 2002 .

[34]  Adam M. Schwartzberg,et al.  Novel Optical Properties and Emerging Applications of Metal Nanostructures , 2008 .

[35]  Bernard S. Gerstman Theoretical modeling of laser-induced explosive pressure generation and vaporization in pigmented cells , 2000, Laser Damage.

[36]  J. West,et al.  Immunotargeted nanoshells for integrated cancer imaging and therapy. , 2005, Nano letters.

[37]  Y. Yamaguchi,et al.  Spectroscopic study of laser-induced phase transition of gold nanoparticles on nanosecond time scales and longer. , 2006, The journal of physical chemistry. B.

[38]  C. V. van Blitterswijk,et al.  Intracellular degradation of microspheres based on cross-linked dextran hydrogels or amphiphilic block copolymers: A comparative Raman microscopy study , 2007, International journal of nanomedicine.

[39]  Ji-Xin Cheng,et al.  Hyperthermic effects of gold nanorods on tumor cells. , 2007, Nanomedicine.

[40]  F. Schotte,et al.  Visualizing chemical reactions in solution by picosecond x-ray diffraction. , 2004, Physical review letters.

[41]  D. Lapotko,et al.  Photothermal properties of gold nanoparticles under exposure to high optical energies , 2008, Nanotechnology.

[42]  Reginald Birngruber,et al.  On the possibility of high-precision photothermal microeffects and the measurement of fast thermal denaturation of proteins , 1999 .

[43]  T. Perkins,et al.  Gold nanoparticles: enhanced optical trapping and sensitivity coupled with significant heating. , 2006, Optics letters.

[44]  Ekaterina Lukianova,et al.  Photothermal responses of individual cells. , 2005, Journal of biomedical optics.

[45]  S. Jacques,et al.  THE MELANOSOME: THRESHOLD TEMPERATURE FOR EXPLOSIVE VAPORIZATION AND INTERNAL ABSORPTION COEFFICIENT DURING PULSED LASER IRRADIATION , 1991, Photochemistry and photobiology.

[46]  R. Barrera,et al.  Optical properties of an eccentrically located pigment within an air bubble , 2004 .

[47]  Reginald Birngruber,et al.  Analysis of cavitation dynamics during pulsed laser tissue ablation by optical on-line monitoring , 1996 .

[48]  Stanislav Emelianov,et al.  Molecular specific optoacoustic imaging with plasmonic nanoparticles. , 2007, Optics express.

[49]  M Shane Hutson,et al.  Plasma and cavitation dynamics during pulsed laser microsurgery in vivo. , 2007, Physical review letters.

[50]  Dakrong Pissuwan,et al.  Therapeutic possibilities of plasmonically heated gold nanoparticles. , 2006, Trends in biotechnology.

[51]  Alexander A. Oraevsky,et al.  Elimination of leukemic cells from human transplants by laser nano-thermolysis , 2006, SPIE BiOS.

[52]  Christian Dahmen,et al.  Laser-induced heating and melting of gold nanoparticles studied by time-resolved x-ray scattering , 2004 .

[53]  M. O’Donnell,et al.  Optical and acoustic detection of laser-generated microbubbles in single cells , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[54]  Xiaohua Huang,et al.  Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles. , 2006, Cancer letters.

[55]  Britton Chance,et al.  Enhanced optical scattering by microbubbles , 1997, Photonics West - Biomedical Optics.

[56]  Hongwei Liao,et al.  Biomedical applications of plasmon resonant metal nanoparticles. , 2006, Nanomedicine.

[57]  Alexander O. Govorov,et al.  Generating heat with metal nanoparticles , 2007 .

[58]  Ekaterina Lukianova,et al.  Selective laser nano‐thermolysis of human leukemia cells with microbubbles generated around clusters of gold nanoparticles , 2006, Lasers in surgery and medicine.

[59]  Duncan J. Maitland,et al.  Modeling of bubble dynamics in relation to medical applications , 1997, Photonics West - Biomedical Optics.

[60]  Charles P. Lin,et al.  Selective cell killing by microparticle absorption of pulsed laser radiation , 1999 .

[61]  Ashley J. Welch,et al.  Excimer laser ablation of soft tissue: a study of the content of rapidly expanding and collapsing bubbles , 1994 .

[62]  Gregory V. Hartland,et al.  Measurements of the material properties of metal nanoparticles by time-resolved spectroscopy , 2004 .

[63]  Park,et al.  Optical reflectance and scattering studies of nucleation and growth of bubbles at a liquid-solid interface induced by pulsed laser heating. , 1993, Physical review letters.

[64]  L. Liz‐Marzán,et al.  Heat dissipation in gold–silica core-shell nanoparticles , 2003 .

[65]  Dmitri O. Lapotko,et al.  Laser-induced micro-bubbles in cells , 2005 .

[66]  A. Plech,et al.  Cavitation dynamics on the nanoscale , 2005 .

[67]  C. Voisin,et al.  Coherent acoustic mode oscillation and damping in silver nanoparticles , 1999 .

[68]  D. P. O'Neal,et al.  Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. , 2004, Cancer letters.

[69]  K Gordon,et al.  Immunophenotyping using gold or silver nanoparticle-polystyrene bead conjugates with multiple light scatter. , 2000, Cytometry.

[70]  Michele Follen,et al.  Real-time vital optical imaging of precancer using anti-epidermal growth factor receptor antibodies conjugated to gold nanoparticles. , 2003, Cancer research.

[71]  Eitan Kimmel,et al.  Modeling photothermal and acoustical induced microbubble generation and growth. , 2007, Ultrasonics.

[72]  A. Vogel,et al.  Femtosecond-laser-induced nanocavitation in water: implications for optical breakdown threshold and cell surgery. , 2008, Physical review letters.

[73]  Ralf Brinkmann,et al.  Nucleation dynamics around single microabsorbers in water heated by nanosecond laser irradiation , 2007 .

[74]  Xunbin Wei,et al.  Selective cell targeting with light-absorbing microparticles and nanoparticles. , 2003, Biophysical journal.

[75]  G. Plessen,et al.  Excitation of nanoscale vapor bubbles at the surface of gold nanoparticles in water. , 2006, The Journal of chemical physics.

[76]  Charles P. Lin,et al.  CAVITATION AND ACOUSTIC EMISSION AROUND LASER-HEATED MICROPARTICLES , 1998 .

[77]  Alexander A. Oraevsky,et al.  Laser activated nanothermolysis of leukemia cells monitored by photothermal microscopy , 2005, SPIE BiOS.

[78]  Xiaohua Huang,et al.  Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. , 2006, Journal of the American Chemical Society.

[79]  Hristina Petrova,et al.  Investigation of the properties of gold nanoparticles in aqueous solution at extremely high lattice temperatures , 2004 .

[80]  J. West,et al.  Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy. , 2007, Nano letters.

[81]  J. Hafner,et al.  Photothermal bubbles as optical scattering probes for imaging living cells. , 2008, Nanomedicine.

[82]  J. Hafner,et al.  LANTCET: elimination of solid tumor cells with photothermal bubbles generated around clusters of gold nanoparticles. , 2008, Nanomedicine.

[83]  K. Sokolowski-Tinten,et al.  Femtosecond melting and ablation of semiconductors studied with time of flight mass spectroscopy , 1999 .

[84]  Masakazu Sugiyama,et al.  Laser-induced shape transformation of gold nanoparticles below the melting point: the effect of surface melting. , 2005, The journal of physical chemistry. B.

[85]  Leonid V. Zhigilei,et al.  Numerical modeling of short pulse laser interaction with Au nanoparticle surrounded by water , 2007 .

[86]  Ekaterina Lukianova,et al.  Method of laser activated nano-thermolysis for elimination of tumor cells. , 2006, Cancer letters.

[87]  T. Dekorsy,et al.  A surface phase transition of supported gold nanoparticles. , 2007, Nano letters.

[88]  Paul L Carson,et al.  Photoacoustic tomography of joints aided by an Etanercept-conjugated gold nanoparticle contrast agent—an ex vivo preliminary rat study , 2008, Nanotechnology.

[89]  A. Welch,et al.  Excimer laser induced bubble: Dimensions, theory, and implications for laser angioplasty , 1996, Lasers in surgery and medicine.

[90]  Z. Somosy,et al.  Biological effect of He‐Ne laser: Investigations on functional and micromorphological alterations of cell membranes, in vitro , 1984, Lasers in surgery and medicine.

[91]  Alexander A. Kokhanovsky,et al.  Optical properties of bubbles , 2002 .

[92]  Duncan J. Maitland,et al.  Computational modeling of stress transient and bubble evolution in short-pulse laser-irradiated melanosome particles , 1997, Photonics West - Biomedical Optics.

[93]  Alaaldin M. Alkilany,et al.  Gold nanoparticles in biology: beyond toxicity to cellular imaging. , 2008, Accounts of chemical research.

[94]  R Richards-Kortum,et al.  Optical Systems for in Vivo Molecular Imaging of Cancer , 2003, Technology in cancer research & treatment.

[95]  Holger Lubatschowski,et al.  Live cell opto-injection by femtosecond laser pulses , 2007, SPIE BiOS.

[96]  Ronald A. Roy,et al.  Nucleating cavitation from laser-illuminated nano-particles , 2005 .

[97]  Gary M. Hansen,et al.  Mie scattering as a technique for the sizing of air bubbles , 1985 .

[98]  Charles P. Lin,et al.  Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen , 2000, Lasers in surgery and medicine.

[99]  Jacques A. Delaire,et al.  Optical Limitation induced by Gold Clusters. 1. Size Effect , 2000 .

[100]  M. Otter Temperaturabhängigkeit der optischen Konstanten massiver Metalle , 1961 .