Modeling neurogenesis impairment in Down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells.

[1]  Elizabeth Head,et al.  Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human down syndrome brains. , 2013, The Journal of Biological Chemistry.

[2]  H. Okano,et al.  Accelerating progress in induced pluripotent stem cell research for neurological diseases , 2012, Annals of neurology.

[3]  S. Orkin,et al.  A Human Stem Cell Model of Early Alzheimer’s Disease Pathology in Down Syndrome , 2012, Science Translational Medicine.

[4]  Ji Young Kim,et al.  Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery , 2011, Experimental & Molecular Medicine.

[5]  Katriina Aalto-Setälä,et al.  Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture , 2011, Disease Models & Mechanisms.

[6]  C. Suschek,et al.  Specific Age-Associated DNA Methylation Changes in Human Dermal Fibroblasts , 2011, PloS one.

[7]  Fred H. Gage,et al.  A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells , 2010, Cell.

[8]  C. Antzelevitch,et al.  Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery. , 2010, Current medicinal chemistry.

[9]  V. Fuster,et al.  Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells. , 2009, Cellular reprogramming.

[10]  Guilai Shi,et al.  Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. , 2009, Human molecular genetics.

[11]  G. Nuovo,et al.  Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains* , 2009, The Journal of Biological Chemistry.

[12]  C. Pereira,et al.  Senescence impairs successful reprogramming to pluripotent stem cells. , 2009, Genes & development.

[13]  C. Atwood,et al.  Differential Processing of Amyloid-β Precursor Protein Directs Human Embryonic Stem Cell Proliferation and Differentiation into Neuronal Precursor Cells* , 2009, The Journal of Biological Chemistry.

[14]  George Q. Daley,et al.  Disease-Specific Induced Pluripotent Stem Cells , 2008, Cell.

[15]  Thomas D. Schmittgen,et al.  Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. , 2008, Biochemical and biophysical research communications.

[16]  Y. Soong,et al.  Functional Network Analysis of the Transcriptomes of Mesenchymal Stem Cells Derived from Amniotic Fluid, Amniotic Membrane, Cord Blood, and Bone Marrow , 2007, Stem cells.

[17]  Anthony Atala,et al.  Isolation of amniotic stem cell lines with potential for therapy , 2007, Nature Biotechnology.

[18]  Suel-Kee Kim,et al.  Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells , 2006, FEBS letters.

[19]  K. Gardiner,et al.  The proteins of human chromosome 21 , 2006, American journal of medical genetics. Part C, Seminars in medical genetics.

[20]  M. Tsai,et al.  Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. , 2004, Human reproduction.

[21]  J. Coyle,et al.  The neurobiologie consequences of down syndrome , 1986, Brain Research Bulletin.

[22]  T. Petit,et al.  Neurobiology of Down's syndrome , 1983, Progress in Neurobiology.

[23]  H. Okano,et al.  [Modeling familial Alzheimer's disease with induced pluripotent stem cells]. , 2012, Rinsho shinkeigaku = Clinical neurology.

[24]  H. Kung,et al.  Targeting S100P Inhibits Colon Cancer Growth and Metastasis by Lentivirus-Mediated RNA Interference and Proteomic Analysis , 2011, Molecular medicine.

[25]  B. Thiers Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2008 .

[26]  M T Davisson,et al.  Segmental trisomy as a mouse model for Down syndrome. , 1993, Progress in clinical and biological research.

[27]  L. Becker,et al.  Growth and development of the brain in Down syndrome. , 1991, Progress in clinical and biological research.