Common genetic variations in the LEP and LEPR genes, obesity and breast cancer incidence and survival

[1]  A. Neugut,et al.  Weight Gain Prior to Diagnosis and Survival from Breast Cancer , 2007, Cancer Epidemiology Biomarkers & Prevention.

[2]  B. Rueda,et al.  Leptin Signaling Promotes the Growth of Mammary Tumors and Increases the Expression of Vascular Endothelial Growth Factor (VEGF) and Its Receptor Type Two (VEGF-R2)* , 2006, Journal of Biological Chemistry.

[3]  C. Ki,et al.  Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea. , 2006, Cancer letters.

[4]  A. Neugut,et al.  Weight Gain Prior to Breast Cancer Diagnosis and Survival , 2006 .

[5]  M. Dieudonné,et al.  Sex steroids and leptin regulate 11β-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes: Sex specificities , 2006, The Journal of Steroid Biochemistry and Molecular Biology.

[6]  R. Catarino,et al.  A functional polymorphism in the promoter region of leptin gene increases susceptibility for non-small cell lung cancer. , 2006, European journal of cancer.

[7]  T. Funahashi,et al.  High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels , 2006, International journal of cancer.

[8]  L. Brinton,et al.  Interrelationships between serum leptin, IGF-1, IGFBP3, C-peptide and prolactin and breast cancer risk in young women , 2006, Breast Cancer Research and Treatment.

[9]  Lotfi Chouchane,et al.  Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma , 2006, BMC Cancer.

[10]  G. Morgan,et al.  Non-Hodgkin's lymphoma, obesity and energy homeostasis polymorphisms , 2005, British Journal of Cancer.

[11]  I. G. Fantus,et al.  Is leptin a mediator of adverse prognostic effects of obesity in breast cancer? , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[12]  A. Neugut,et al.  Body size changes in relation to postmenopausal breast cancer among women on Long Island, New York. , 2005, American journal of epidemiology.

[13]  E. Taioli,et al.  Genetics of leptin and obesity: a HuGE review. , 2005, American journal of epidemiology.

[14]  S. Loi,et al.  Obesity and Outcomes in Premenopausal and Postmenopausal Breast Cancer , 2005, Cancer Epidemiology Biomarkers & Prevention.

[15]  P. Albert,et al.  Common Leptin Receptor Polymorphisms do not Modify the Effect of Alcohol Ingestion on Serum Leptin Levels in a Controlled Feeding and Alcohol Ingestion Study , 2005, Cancer Epidemiology Biomarkers & Prevention.

[16]  L. Robison,et al.  Genetic variation in the leptin receptor gene and obesity in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  P. Stattin,et al.  Plasma Leptin and Breast Cancer Risk: A Prospective Study in Northern Sweden , 2004, Breast Cancer Research and Treatment.

[18]  T. Saruta,et al.  Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. , 2004, Metabolism: clinical and experimental.

[19]  H. Nagawa,et al.  Enhanced Expression of Leptin and Leptin Receptor (OB-R) in Human Breast Cancer , 2004, Clinical Cancer Research.

[20]  D. Pinto,et al.  Overexpressing leptin genetic polymorphism (−2548 G/A) is associated with susceptibility to prostate cancer and risk of advanced disease , 2004, The Prostate.

[21]  M. Forrest,et al.  Body mass index, leptin and leptin receptor polymorphisms, and non-hodgkin lymphoma. , 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[22]  Xin Hu,et al.  Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development. , 2003, Journal of the National Cancer Institute.

[23]  C. Longcope,et al.  Serum sex hormones and breast cancer risk factors in postmenopausal women. , 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[24]  R. Casamitjana,et al.  Interactions between serum leptin, the insulin‐like growth factor‐I system, and sex, age, anthropometric and body composition variables in a healthy population randomly selected , 2003, Clinical endocrinology.

[25]  D. Rose,et al.  Breast Cancer and Obesity: An Update , 2003, Nutrition and cancer.

[26]  M. Baratta.  Leptin--from a signal of adiposity to a hormonal mediator in peripheral tissues. , 2002, Medical science monitor : international medical journal of experimental and clinical research.

[27]  D. Rose,et al.  Adverse effects of obesity on breast cancer prognosis, and the biological actions of leptin (review). , 2002, International journal of oncology.

[28]  S. Mottagui-Tabar,et al.  A Polymorphism in the Leptin Promoter Region (-2548 G/A) Influences Gene Expression and Adipose Tissue Secretion of Leptin , 2002, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[29]  Mary Beth Terry,et al.  The Long Island Breast Cancer Study Project: Description of a Multi-Institutional Collaboration to Identify Environmental Risk Factors for Breast Cancer , 2002, Breast Cancer Research and Treatment.

[30]  A. McTiernan,et al.  Weight loss in breast cancer patient management. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[31]  J. Chan,et al.  The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability. , 2001, The Journal of clinical endocrinology and metabolism.

[32]  A. Astrup,et al.  Obesity : Preventing and managing the global epidemic , 2000 .

[33]  G. Siest,et al.  Association of the G‐2548A polymorphism in the 5′ region of the LEP gene with overweight , 2000, Annals of human genetics.

[34]  Cai Li,et al.  Leptin: a multifunctional hormone , 2000, Cell Research.

[35]  D. Trichopoulos,et al.  Leptin and insulin growth factor I in relation to breast cancer (Greece) , 2000, Cancer Causes & Control.

[36]  C. Mantzoros,et al.  Leptin in relation to carcinoma In situ of the breast: A study of pre‐menopausal cases and controls , 1999, International journal of cancer.

[37]  A. R. Frisancho.  Physical Status: The Use and Interpretation of Anthropometry , 1996, The American Journal of Clinical Nutrition.

[38]  Paul D. Allison,et al.  Survival analysis using sas®: a practical guide , 1995 .

[39]  S. Woods,et al.  Model for the regulation of energy balance and adiposity by the central nervous system. , 1995, The American journal of clinical nutrition.

[40]  M. Deitel,et al.  Increased obese mRNA expression in omental fat cells from massively obese humans , 1995, Nature Medicine.

[41]  M. Maffei,et al.  Positional cloning of the mouse obese gene and its human homologue , 1994, Nature.

[42]  J. Friedman,et al.  Molecular mapping of the mouse ob mutation. , 1991, Genomics.

[43]  D. Hosmer,et al.  Applied Logistic Regression , 1991 .

[44]  D. Coleman.  Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice , 1978, Diabetologia.

[45]  Joseph Waksberg,et al.  Sampling Methods for Random Digit Dialing , 1978 .

[46]  C. Bouchard,et al.  Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study. , 2000, The Journal of clinical endocrinology and metabolism.

[47]  Who Consultation on Obesity.  Obesity: preventing and managing the global epidemic. Report of a WHO consultation. , 2000, World Health Organization technical report series.

[48]  S B Heymsfield,et al.  Uses and interpretation of anthropometry in the elderly for the assessment of physical status. Report to the Nutrition Unit of the World Health Organization: the Expert Subcommittee on the Use and Interpretation of Anthropometry in the Elderly. , 1998, The journal of nutrition, health & aging.

[49]  M. Maffei,et al.  Positional cloning of the mouse obese gene and its human homologue , 1995, Nature.