Clinical Case of Endocarditis due to Trichosporon inkin and Antifungal Susceptibility Profile of the Organism

ABSTRACT A fatal case of Trichosporon inkin prosthetic endocarditis is reported. The isolation sites and susceptibility profiles of 10 other isolates are also reviewed. Four strains were recovered from cutaneous or subcutaneous samples, four were recovered from urine, one was recovered from peritoneal liquid, and one was recovered from bone. Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 μg/ml, respectively.

[1]  S. H. Alves,et al.  Trichosporon inkin peritonitis during continuous ambulatory peritoneal dialysis with bibliography review , 2004, Mycopathologia.

[2]  D. Denning,et al.  Method for the determination of minimum inhibitory concentration (MIC) by broth dilution of fermentative yeasts , 2003 .

[3]  G. Cooper,et al.  Effect of temperature on the Brugada ECG , 2003, Heart.

[4]  Crowther Ks,et al.  Trichosporon inkin peritonitis in a patient on continuous ambulatory peritoneal dialysis returning from the Caribbean. , 2003 .

[5]  P. Mcwhinney,et al.  Trichosporon inkin peritonitis in a patient on continuous ambulatory peritoneal dialysis returning from the Caribbean. , 2003, Clinical nephrology.

[6]  J. Sobel,et al.  Vulvovaginal Trichosporonosis , 2003, Infectious diseases in obstetrics and gynecology.

[7]  H. Dombret,et al.  Use of Voriconazole to Successfully Treat Disseminated Trichosporon asahii Infection in a Patient with Acute Myeloid Leukaemia , 2002, European Journal of Clinical Microbiology and Infectious Diseases.

[8]  K. Sepkowitz,et al.  Breakthrough trichosporonosis in a bone marrow transplant recipient receiving caspofungin acetate. , 2002, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[9]  G. Hasçelik,et al.  Comparison of NCCLS microdilution method and Etest in antifungal susceptibility testing of clinical Trichosporon asahii isolates. , 2002, Diagnostic microbiology and infectious disease.

[10]  J. Rex,et al.  In Vitro Antifungal Susceptibilities of Trichosporon Species , 2002, Antimicrobial Agents and Chemotherapy.

[11]  D. Wolf,et al.  Multidrug-Resistant Trichosporon asahii Infection of Nongranulocytopenic Patients in Three Intensive Care Units , 2001, Journal of Clinical Microbiology.

[12]  G. Araj,et al.  A Case of Trichosporon beigelii Endocarditis , 2001, European Journal of Clinical Microbiology and Infectious Diseases.

[13]  M. Miyaji,et al.  Trichosporon species infection in bone marrow transplanted patients. , 2001, Diagnostic microbiology and infectious disease.

[14]  E. Shlasko,et al.  Trichosporon inkin lung abscesses presenting as a penetrating chest wall mass. , 2000, The Pediatric infectious disease journal.

[15]  M. Cawley,et al.  Trichosporon beigelii infection: experience in a regional burn center. , 2000, Burns : journal of the International Society for Burn Injuries.

[16]  M. Cuenca‐Estrella,et al.  Influence of Shaking on Antifungal Susceptibility Testing of Cryptococcus neoformans: a Comparison of the NCCLS Standard M27A Medium, Buffered Yeast Nitrogen Base, and RPMI–2% Glucose , 2000, Antimicrobial Agents and Chemotherapy.

[17]  D. Yarrow Methods for the isolation, maintenance and identification of yeasts , 1998 .

[18]  C. Douchet,et al.  Trichosporon inkin endocarditis: short-term evolution and clinical report. , 1996, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[19]  M. Kombila,et al.  White piedra and Trichosporon species in equatorial Africa. I. History and clinical aspects: an analysis of 449 superficial inguinal specimens , 1994, Mycoses.

[20]  C. Douchet,et al.  White piedra and Trichosporon species in equatorial Africa. II. Clinical and mycological associations: an analysis of 449 superficial inguinal specimens , 1994, Mycoses.

[21]  G. S. Hoog,et al.  Trichosporon on humans: a practical account , 1994, Mycoses.

[22]  M. Ghannoum,et al.  Susceptibility testing of Cryptococcus neoformans: a microdilution technique , 1992, Journal of clinical microbiology.

[23]  T. Walsh,et al.  Distinction of deep versus superficial clinical and nonclinical isolates of Trichosporon beigelii by isoenzymes and restriction fragment length polymorphisms of rDNA generated by polymerase chain reaction , 1991, Journal of clinical microbiology.

[24]  T. Walsh,et al.  Patterns of morphologic variation among isolates of Trichosporon beigelii , 1990, Journal of clinical microbiology.

[25]  K. Kwon-Chung,et al.  Invasive infection with Sarcinosporon inkin in a patient with chronic granulomatous disease. , 1990, American journal of clinical pathology.

[26]  T. Walsh,et al.  Trichosporon beigelii, an emerging pathogen resistant to amphotericin B , 1990, Journal of clinical microbiology.

[27]  E. Bruck,et al.  National Committee for Clinical Laboratory Standards. , 1980, Pediatrics.