Intestinal Drug Absorption and Metabolism in Cell Cultures: Caco-2 and Beyond

[1]  R. Borchardt The application of cell culture systems in drug discovery and development. , 1995, Journal of drug targeting.

[2]  A. Quaroni,et al.  Development of intestinal cell culture models for drug transport and metabolism studies , 1996 .

[3]  Ronald T. Borchardt,et al.  Models for Assessing Drug Absorption and Metabolism , 1996, Pharmaceutical Biotechnology.

[4]  Grant D. Green,et al.  Chapter 33. Recent Advances in the Generation of Molecular Diversity , 1993 .

[5]  Shiyin Yee,et al.  In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth , 1997, Pharmaceutical Research.

[6]  T. Kissel,et al.  Heterogeneity in the human intestinal cell line Caco-2 leads to differences in transepithelial transport , 1995 .

[7]  A. J. Shaw Epithelial cell culture : a practical approach , 1996 .

[8]  R. Batey,et al.  Immunologic, functional, and morphological characterization of three new human small intestinal epithelial cell lines. , 1996, Gastroenterology.

[9]  P. Artursson,et al.  Cell cultures to assess drug transport and metabolism - Preface , 1996 .

[10]  P. Artursson,et al.  Co-cultures of human intestinal goblet (HT29-H) and absorptive (Caco-2) cells for studies of drug and peptide absorption , 1995 .

[11]  Intestinal Absorption Screening of Mixtures from Combinatorial Libraries in the Caco-2 Model , 1997, Pharmaceutical Research.

[12]  B. W. Penman,et al.  Development of Caco-2 Cells Expressing High Levels of cDNA-Derived Cytochrome P4503A4 , 1996, Pharmaceutical Research.

[13]  Per Artursson,et al.  A Drug Absorption Model Based on the Mucus Layer Producing Human Intestinal Goblet Cell Line HT29-H , 1993, Pharmaceutical Research.

[14]  P. Watkins,et al.  Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3. , 1997, Molecular pharmacology.

[15]  J. Kraehenbuhl,et al.  Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. , 1997, Science.