Evolutionary Modular Neural Network Approach for Breast Cancer Diagnosis

Knowledge Discovery paradigms especially Soft Computing techniques like Artificial Neural Networks have been at the fore front of research aimed at solving the problem areas involved in many diverse fields of application. Automated diagnosis of deadly diseases is one of such fields that have seen much effort from researchers in the last few years. One area where this effort has been most felt is the diagnosis of breast cancer in women. However, development of a computationally efficient, detection-wise effective and robust framework for the diagnosis of breast cancer has still not materialized. The major problem here is the presence of a number of decision variables involved that makes this problem of diagnosis much more complex and intricate. This makes it difficult to be tackled by traditional computing paradigms efficiently. In this paper, we explain how the paradigms of modularity and optimization using evolutionary technique could be used to solve the aforesaid problem with significant success. Here, to take benefit of modularity, we make of use modular neural network instead of the traditional monolithic neural network for the recognition of input vectors implying breast cancer. Also, to make the architecture more optimal, we make use of genetic algorithms to achieve optimal connections (weights) among the neurons in each of the individual experts of the modular neural network. Experimental results show that the proposed approach has been significantly successful in dealing with aforesaid problem of breast cancer diagnosis with a training accuracy of 95.97% and testing accuracy of 96.5%. That is well above what shown by traditional approaches as described later on.

[1]  F. Schnorrenberg,et al.  Improved detection of breast cancer nuclei using modular neural networks. , 2000, IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society.

[2]  Nikola Gradojevic,et al.  Option Pricing With Modular Neural Networks , 2009, IEEE Transactions on Neural Networks.

[3]  D. Chen,et al.  Breast cancer diagnosis using self-organizing map for sonography. , 2000, Ultrasound in medicine & biology.

[4]  Patricia Melin,et al.  Optimization of Modular Neural Network, Using Genetic Algorithms: The Case of Face and Voice Recognition , 2008, Soft Computing for Hybrid Intelligent Systems.

[5]  Padhraic Smyth,et al.  From Data Mining to Knowledge Discovery: An Overview , 1996, Advances in Knowledge Discovery and Data Mining.

[6]  W. Moon,et al.  Computer‐aided diagnosis using morphological features for classifying breast lesions on ultrasound , 2008, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[7]  Jiawei Han,et al.  Data Mining: Concepts and Techniques , 2000 .

[8]  Patricia Melin,et al.  A Modular Neural Network with Fuzzy Response Integration for Person Identification Using Biometric Measures , 2009, Evolutionary Design of Intelligent Systems in Modeling, Simulation and Control.

[9]  Anupam Shukla,et al.  Fusion of Speech and Face by Enhanced Modular Neural Network , 2010, ICISTM.

[10]  Daniel T. Larose,et al.  Discovering Knowledge in Data: An Introduction to Data Mining , 2005 .

[11]  Patricia Melin,et al.  A hybrid modular neural network architecture with fuzzy Sugeno integration for time series forecasting , 2007, Appl. Soft Comput..

[12]  Elif Derya Übeyli A Mixture of Experts Network Structure for Breast Cancer Diagnosis , 2005, Journal of Medical Systems.

[13]  Witold Pedrycz,et al.  Soft Computing for Hybrid Intelligent Systems , 2008, Soft Computing for Hybrid Intelligent Systems.

[14]  Mann A. Shoffner,et al.  Application of backpropagation neural networks to diagnosis of breast and ovarian cancer. , 1994, Cancer letters.

[15]  Dorothea Heiss-Czedik,et al.  An Introduction to Genetic Algorithms. , 1997, Artificial Life.

[16]  Mehmet Fatih Akay,et al.  Support vector machines combined with feature selection for breast cancer diagnosis , 2009, Expert Syst. Appl..

[17]  Farooq Azam,et al.  Biologically Inspired Modular Neural Networks , 2000 .

[18]  X. Yao Evolving Artificial Neural Networks , 1999 .

[19]  K. Satya Prasad,et al.  AUTOMATIC DETECTION OF BREAST CANCER MASS IN MAMMOGRAMS USING MORPHOLOGICAL OPERATORS AND FUZZY C -MEANS CLUSTERING , 2009 .

[20]  Y. Wu,et al.  Artificial neural networks in mammography: application to decision making in the diagnosis of breast cancer. , 1993, Radiology.

[21]  Valerie Andolina,et al.  Mammographic Imaging: A Practical Guide , 2001 .

[22]  Patricia Melin,et al.  Modular Neural Networks for Person Recognition Using the Contour Segmentation of the Human Iris Biometric Measurement , 2010, Soft Computing for Recognition Based on Biometrics.

[23]  Marios A. Gavrielides,et al.  Computer-aided classification of breast microcalcification clusters: merging of features from image processing and radiologists , 2003, SPIE Medical Imaging.

[24]  Margaret H. Dunham,et al.  Data Mining: Introductory and Advanced Topics , 2002 .

[25]  M. Cevdet Ince,et al.  An expert system for detection of breast cancer based on association rules and neural network , 2009, Expert Syst. Appl..

[26]  Tulay Yildirim,et al.  BREAST CANCER DIAGNOSIS USING STATISTICAL NEURAL NETWORKS , 2004 .

[27]  Rangaraj M. Rangayyan,et al.  DETECTION AND CLASSIFICATION OF MAMMOGRAPHIC CALCIFICATIONS , 1993 .

[28]  Jian Pei,et al.  Data Mining: Concepts and Techniques, 3rd edition , 2006 .