Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
暂无分享,去创建一个
D. Absher | L. Waite | R. Kimberly | Xinrui Li | A. Gibson | J. Edberg | W. Chatham | Kevin Roberts | Lindsay L. Waite | W. Winn Chatham | Robert P. Kimberly
[1] J. Nossent,et al. Circulating interferon-α2 levels are increased in the majority of patients with systemic lupus erythematosus and are associated with disease activity and multiple cytokine activation , 2013, Lupus.
[2] G. Alarcón,et al. Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary population. , 2012, Arthritis and rheumatism.
[3] E. Chuang,et al. A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity , 2011, Genes and Immunity.
[4] Gerald McGwin,et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. , 2012, Arthritis and rheumatism.
[5] Jonathan D. Wren,et al. Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus , 2011, Epigenetics.
[6] P. Sham,et al. Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus , 2010, PLoS genetics.
[7] Fatima Al-Shahrour,et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. , 2010, Genome research.
[8] Gerald McGwin,et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus , 2009, Nature Genetics.
[9] Ying Wang,et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus , 2009, Nature Genetics.
[10] T. Behrens,et al. Review of recent genome‐wide association scans in lupus , 2009, Journal of internal medicine.
[11] Shizhong Han,et al. Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus , 2008, PloS one.
[12] J. Harley,et al. High serum IFN-α activity is a heritable risk factor for systemic lupus erythematosus , 2007, Genes and Immunity.
[13] M. Peterson,et al. Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. , 2005, Arthritis and rheumatism.
[14] Marta E Alarcón-Riquelme,et al. Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. , 2005, Arthritis and rheumatism.
[15] M. Peterson,et al. Coordinate overexpression of interferon‐α–induced genes in systemic lupus erythematosus , 2004 .
[16] G. Karypis,et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[17] S. Hanash,et al. Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. , 2001, Arthritis and rheumatism.
[18] M. Hochberg,et al. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. , 1997, Arthritis and rheumatism.
[19] E. Amento,et al. Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. , 1993, The Journal of clinical investigation.
[20] T. Mack,et al. A revised estimate of twin concordance in systemic lupus erythematosus. , 1992, Arthritis and rheumatism.
[21] S Hanash,et al. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. , 1990, Arthritis and rheumatism.
[22] S. Hanash,et al. Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. , 1988, Journal of immunology.
[23] Lawrence Js,et al. A family survey of lupus erythematosus. 1. Heritability. , 1987 .
[24] J F Fries,et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. , 1982, Arthritis and rheumatism.
[25] Hong Zhang,et al. Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus. , 2012, Arthritis and rheumatism.
[26] C. Martins,et al. A family survey of lupus erythematosus. 1. Heritability. , 1987, The Journal of rheumatology.