Selective accumulation of α-tocopherol in Drosophila is associated with cytochrome P450 tocopherol-ω-hydroxylase activity but not α-tocopherol transfer protein

[1]  R. Parker,et al.  Long-chain carboxychromanols are the major metabolites of tocopherols and tocotrienols in A549 lung epithelial cells but not HepG2 cells. , 2005, The Journal of nutrition.

[2]  R. Parker,et al.  The cytotoxicity of vitamin E is both vitamer- and cell-specific and involves a selectable trait. , 2004, The Journal of nutrition.

[3]  R. Parker,et al.  Discovery, Characterization, and Significance of the Cytochrome P450 ω‐Hydroxylase Pathway of Vitamin E Catabolism , 2004, Annals of the New York Academy of Sciences.

[4]  Yoshiro Saito,et al.  Cell Death Caused by Selenium Deficiency and Protective Effect of Antioxidants* , 2003, Journal of Biological Chemistry.

[5]  Rachel J Parsons,et al.  Ligand specificity in the CRAL-TRIO protein family. , 2003, Biochemistry.

[6]  Tetsuo Satoh,et al.  Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. , 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[7]  P. Pfluger,et al.  Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells. , 2002, The Journal of nutrition.

[8]  M. Kusunose,et al.  Prostaglandin and leukotriene ω-hydroxylases , 2002 .

[9]  R. Parker,et al.  Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status. , 2002, The Journal of biological chemistry.

[10]  Robert V Farese,et al.  Incorporation of deuterated RRR- or all-rac-α-tocopherol in plasma and tissues of α-tocopherol transfer protein–null mice , 2002 .

[11]  R. Parker,et al.  Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin. , 2000, Biochemical and biophysical research communications.

[12]  J. G. Scott,et al.  Expression and activity of a house‐fly cytochrome P450, CYP6D1, in Drosophila melanogaster , 2000, Insect molecular biology.

[13]  R. Parker,et al.  A novel 5'-carboxychroman metabolite of gamma-tocopherol secreted by HepG2 cells and excreted in human urine. , 2000, Biochemical and biophysical research communications.

[14]  J. Fox,et al.  Expression of the CYP4F3 Gene , 1999, The Journal of Biological Chemistry.

[15]  R. Parker,et al.  Urinary excretion of 2,7, 8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman is a major route of elimination of gamma-tocopherol in humans. , 1999, Journal of lipid research.

[16]  E. Hodgson,et al.  Interactions of Piperonyl Butoxide with Cytochrome P450 , 1999 .

[17]  Hiroyuki Arai,et al.  Affinity for α‐tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs , 1997, FEBS letters.

[18]  E. D. Murray,et al.  A new endogenous natriuretic factor: LLU-alpha. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[19]  M. Traber Determinants of plasma vitamin E concentrations. , 1994, Free radical biology & medicine.

[20]  B. Gassmann,et al.  A novel metabolite of RRR‐α‐tocopherol in human urine , 1993 .

[21]  H. Arai,et al.  Purification and characterization of the α‐tocopherol transfer protein from rat liver , 1991 .

[22]  N. Gualde,et al.  Cyclooxygenase and lipoxygenase-like activity in Drosophila melanogaster. , 1986, Prostaglandins.

[23]  K. Hamamura,et al.  Novel urinary metabolite of d-delta-tocopherol in rats. , 1984, Journal of lipid research.