Numerical Analysis on the Hemodynamics and Leaflet Dynamics in a Bileaflet Mechanical Heart Valve Using a Fluid-Structure Interaction Method

Bileaflet mechanical heart valves (BMHVs) are widely implanted to replace diseased heart valves but still suffer from complications such as hemolysis and platelet activation. These complications are closely related to both flow characteristics through the valves and leaflet dynamics. In this study, a fluid-structure interaction (FSI) simulation is performed to investigate the characteristics of physiological flow interacting with moving leaflets in a BMHV. The present FSI model uses both a finite volume computational fluid dynamics code and a finite element structure dynamics code to solve the governing equations for fluid flow and leaflet dynamics. In addition, a structural analysis is performed with the forces acting on the leaflet surfaces. From the analysis, detailed flow information and leaflet behavior are quantified for a cardiac cycle. The results show that the present FSI model performs well at predicting the overall flow patterns interacting with the moving leaflets and leaflet behavior in the BMHV.

[1]  E. Tatsumi,et al.  Characteristics of cavitation intensity in a mechanical heart valve using a pulsatile device: synchronized analysis between visual images and pressure signals , 2008, Journal of Artificial Organs.

[2]  Fotis Sotiropoulos,et al.  Curvilinear immersed boundary method for simulating fluid structure interaction with complex 3D rigid bodies , 2008, J. Comput. Phys..

[3]  J D Hellums,et al.  Red blood cell damage by shear stress. , 1972, Biophysical journal.

[4]  Fotis Sotiropoulos,et al.  Flow in Prosthetic Heart Valves: State-of-the-Art and Future Directions , 2005, Annals of Biomedical Engineering.

[5]  Yong Zhao,et al.  Particle Image Velocimetry Study of Pulsatile Flow in Bi-leaflet Mechanical Heart Valves with Image Compensation Method , 2007, Journal of biological physics.

[6]  Yong Zhao,et al.  Numerical simulation of opening process in a bileaflet mechanical heart valve under pulsatile flow condition. , 2003, The Journal of heart valve disease.

[7]  Arati Nanda Pati,et al.  Fluid-structure interaction for a pressure driven flow , 2008, Math. Comput. Model..

[8]  Umberto Morbiducci,et al.  Numerical simulation of the dynamics of a bileaflet prosthetic heart valve using a fluid-structure interaction approach. , 2008, Journal of biomechanics.

[9]  J. Halleux,et al.  An arbitrary lagrangian-eulerian finite element method for transient dynamic fluid-structure interactions , 1982 .

[10]  A. J. Thubrikar,et al.  Effect of the sinus geometry on the dynamics of bioprosthetic heart valves , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[11]  Richard L. Leask,et al.  Mechanical heart valve prostheses , 2003 .

[12]  Hélène A. Simon,et al.  Vorticity dynamics of a bileaflet mechanical heart valve in an axisymmetric aorta , 2007 .

[13]  K. Liew,et al.  Numerical simulation of 3D fluid-structure interaction flow using an immersed object method with overlapping grids , 2007 .

[14]  Rui Cheng,et al.  Two-dimensional fluid-structure interaction simulation of bileaflet mechanical heart valve flow dynamics. , 2003, The Journal of heart valve disease.

[15]  R. Cheng,et al.  Three-Dimensional Fluid-Structure Interaction Simulation of Bileaflet Mechanical Heart Valve Flow Dynamics , 2004, Annals of Biomedical Engineering.

[16]  M T Ahmadian,et al.  Time-dependent analysis of leaflets in mechanical aortic bileaflet heart valves in closing phase using the finite strip method. , 2006, Medical engineering & physics.

[17]  Srinivas Aluri,et al.  Mechanical valve closing dynamics: Relationship between velocity of closing, pressure transients, and cavitation initiation , 1997, Annals of Biomedical Engineering.

[18]  H. S. Udaykumar,et al.  Two-Dimensional Dynamic Simulation of Platelet Activation During Mechanical Heart Valve Closure , 2006, Annals of Biomedical Engineering.

[19]  T. Schmitz-Rode,et al.  The geometry of the aortic root in health, at valve disease and after valve replacement. , 1990, Journal of biomechanics.

[20]  M Jones,et al.  In vitro velocity and turbulence measurements in the vicinity of three new mechanical aortic heart valve prostheses: Björk-Shiley Monostrut, Omni-Carbon, and Duromedics. , 1988, The Journal of thoracic and cardiovascular surgery.

[21]  Ajit P Yoganathan,et al.  Microflow fields in the hinge region of the CarboMedics bileaflet mechanical heart valve design. , 2002, The Journal of thoracic and cardiovascular surgery.

[22]  H Harasaki,et al.  Particle image velocimetry investigation of intravalvular flow fields of a bileaflet mechanical heart valve in a pulsatile flow. , 2000, The Journal of heart valve disease.

[23]  Philippe Pibarot,et al.  New insights into the assessment of the prosthetic valve performance in the presence of subaortic stenosis through a fluid-structure interaction model. , 2007, Journal of biomechanics.

[24]  I. Krukenkamp,et al.  Free emboli formation in the wake of bi-leaflet mechanical heart valves and the effects of implantation techniques. , 2002, Journal of biomechanics.

[25]  Miguel Cerrolaza,et al.  A biofluid dynamic computer code using the general lattice Boltzmann equation , 2008, Adv. Eng. Softw..

[26]  C. Peskin Flow patterns around heart valves: A numerical method , 1972 .

[27]  Fotis Sotiropoulos,et al.  Characterization of Hemodynamic Forces Induced by Mechanical Heart Valves: Reynolds vs. Viscous Stresses , 2008, Annals of Biomedical Engineering.

[28]  J.,et al.  Whitaker Lecture : Biorheology in Thrombosis Research , 2022 .

[29]  Fotis Sotiropoulos,et al.  A numerical method for solving the 3D unsteady incompressible Navier-Stokes equations in curvilinear domains with complex immersed boundaries , 2007, J. Comput. Phys..

[30]  H. Reul,et al.  Estimation of Shear Stress-related Blood Damage in Heart Valve Prostheses - in Vitro Comparison of 25 Aortic Valves , 1990, The International journal of artificial organs.

[31]  M. Herrera,et al.  Lattice Boltzmann dynamic simulation of a mechanical heart valve device , 2007, Math. Comput. Simul..

[32]  Ajit Yoganathan,et al.  An in vitro assessment by means of laser Doppler velocimetry of the medtronic advantage bileaflet mechanical heart valve hinge flow. , 2003, The Journal of thoracic and cardiovascular surgery.

[33]  J. D. Hellums,et al.  1993 Whitaker lecture: Biorheology in thrombosis research , 1994, Annals of Biomedical Engineering.

[34]  Elias Balaras,et al.  An embedded-boundary formulation for large-eddy simulation of turbulent flows interacting with moving boundaries , 2006, J. Comput. Phys..

[35]  Ajit P Yoganathan,et al.  Fluid mechanics of heart valves. , 2004, Annual review of biomedical engineering.

[36]  René M. Botnar,et al.  Prosthetic heart valve evaluation by magnetic resonance imaging. , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[37]  A. Przekwas,et al.  Pressure-based high-order TVD methodology for dynamic stall simulation , 1993 .

[38]  N. Hwang,et al.  Occluder closing behavior: a key factor in mechanical heart valve cavitation. , 1994, The Journal of heart valve disease.