Multi-level biomedical ontology-enabled service broker for web-based interoperation

Web services have recently become a new trend for gathering biomedical information. However, it is not easy to integrate and obtain a concise/complete query result among hundreds of services. In this paper, we propose a multi-level ontology-enabled service broker architecture for dynamically integrating web services in the biomedical domain. By incorporating temporal concept, new enhanced QoS parameters allow service requesters to control more querying factors in order to precisely invoke corresponding service operations. We also define a Unified Biomedical Service Interface (UBSI) as a service deployment standard. Our ultimate goal is to construct a public, scalable, and interoperable biomedical service platform based on UBSI to benefit scientists in data searching and publishing.