Has the therapeutical ceiling been reached in Crohn's disease randomized controlled trials? A systematic review and meta‐analysis
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L. Peyrin-Biroulet | S. Danese | V. Jairath | F. Magro | A. Dignass | Isabel Marcolino da Silva | C. Dias | C. Alves | M. M. Estevinho | J. Roseira | M. Santiago | P. Moreira | Gaia Catalano | M. Estevinho
[1] D. Rubin,et al. Guselkumab for the treatment of Crohn's disease: Induction results from the Phase 2 GALAXI-1 study. , 2022, Gastroenterology.
[2] E. Loftus,et al. Systematic Review With Meta-analysis: Safety and Effectiveness of Combining Biologics and Small Molecules in Inflammatory Bowel Disease , 2022, Crohn's & colitis 360.
[3] P. Higgins,et al. Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients with Crohn's Disease. , 2021, Gastroenterology.
[4] G. Kaplan,et al. Efficacy of biologic drugs in short-duration versus long-duration inflammatory bowel disease: A systematic review and an individual-patient data meta-analysis of randomized controlled trials. , 2021, Gastroenterology.
[5] S. Vermeire,et al. Efficacy and Safety of Subcutaneous Vedolizumab in Patients With Moderately to Severely Active Crohn’s Disease: Results From the VISIBLE 2 Randomised Trial , 2021, Journal of Crohn's & colitis.
[6] Harminder Singh,et al. AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. , 2021, Gastroenterology.
[7] S. Mehandru,et al. Rational Combination Therapy to Overcome the Plateau of Drug Efficacy in Inflammatory Bowel Disease. , 2021, Gastroenterology.
[8] Jana G Hashash,et al. Positioning biologics in the management of moderate to severe Crohn's disease , 2021, Current opinion in gastroenterology.
[9] T. Matsui,et al. Effects of vedolizumab in Japanese patients with Crohn’s disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses , 2019, Journal of Gastroenterology.
[10] J. Stapelbroek,et al. UEG Week 2019 Oral Presentations , 2019, United European gastroenterology journal.
[11] S. McCartney,et al. Biologic therapies for Crohn’s disease: optimising the old and maximising the new , 2019, F1000Research.
[12] M. Oda,et al. UEG Week 2017 Oral Presentations , 2017, United European Gastroenterology Journal.
[13] K. Papadakis,et al. Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics , 2017, Gut and liver.
[14] A. Kaser,et al. Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study , 2017, The Lancet.
[15] P. Rutgeerts,et al. Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease. , 2016, The New England journal of medicine.
[16] P. Poitras,et al. Biologics in inflammatory bowel disease: what are the data? , 2015, United European gastroenterology journal.
[17] L. Peyrin-Biroulet,et al. Biologic agents for IBD: practical insights , 2015, Nature Reviews Gastroenterology &Hepatology.
[18] J. Xu,et al. Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed. , 2014, Gastroenterology.
[19] Kristin Stephens,et al. Vedolizumab as induction and maintenance therapy for Crohn's disease. , 2013, The New England journal of medicine.
[20] G. Greenberg,et al. Ustekinumab induction and maintenance therapy in refractory Crohn's disease. , 2012, The New England journal of medicine.
[21] P. Rutgeerts,et al. Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. , 2012, Gastroenterology.
[22] T. Hibi,et al. Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's disease. , 2012, Journal of Crohn's & colitis.
[23] P. Rutgeerts,et al. Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial. , 2011, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[24] Michele Tarsilla. Cochrane Handbook for Systematic Reviews of Interventions , 2010, Journal of MultiDisciplinary Evaluation.
[25] R. Bloomfeld,et al. An analysis of the placebo effect in Crohn’s disease over time , 2010, Alimentary pharmacology & therapeutics.
[26] D. Moher,et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. , 2010, International journal of surgery.
[27] S. Schreiber,et al. Certolizumab pegol for the treatment of Crohn's disease. , 2007, The New England journal of medicine.
[28] S. Schreiber,et al. Maintenance therapy with certolizumab pegol for Crohn's disease. , 2007, The New England journal of medicine.
[29] S. Hanauer,et al. Adalimumab Induction Therapy for Crohn Disease Previously Treated with Infliximab , 2007, Annals of Internal Medicine.
[30] P. Rutgeerts,et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. , 2007, Gastroenterology.
[31] J. Mary,et al. Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial. , 2006, Gastroenterology.
[32] P. Rutgeerts,et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. , 2006, Gastroenterology.
[33] S. Schreiber,et al. A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. , 2005, Gastroenterology.
[34] A. Innes,et al. Intravenous CDP870, a PEGylated Fab′ fragment of a humanized antitumour necrosis factor antibody, in patients with moderate‐to‐severe Crohn's disease: an exploratory study , 2004, Alimentary pharmacology & therapeutics.
[35] S. Hanauer,et al. For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .
[36] E. Vasiliauskas,et al. Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. , 1999, Gastroenterology.
[37] S. Targan,et al. A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease , 1997 .
[38] S. Targan,et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. , 1997, The New England journal of medicine.
[39] G. Tytgat,et al. Tumour-necrosis-factor antibody treatment in Crohn's disease , 1993, The Lancet.