Caloric homeostasis and disorders of fuel transport.

FAT and carbohydrate are the major metabolic fuels. With a few exceptions, the various tissues of the body can burn either efficiently, but the amounts used tend to vary in reciprocal fashion under different nutritional conditions and with changing demands for energy.1 Thus, it is not surprising that disturbed metabolism of one is often associated with changes in metabolism of the other. It is the purpose of this essay to review the normal relations between supply and use of these fuels and to describe and, where possible, to explain the changes in lipid transport and metabolism that accompany disturbances in . . .