Cell Manipulations in EWD

It is a general trend in biotechnology that microsystem developments evolve toward the study of cells. DMF follows this trend, and an additional chapter (Chapter 9) on this topic has been introduced in this new edition. The concepts of virtual wells and fixed hydrogel disks are presented and discussed.

[1]  A. Wheeler,et al.  Digital microfluidics for cell-based assays. , 2008, Lab on a chip.

[2]  D. Leckband,et al.  Cell migration and polarity on microfabricated gradients of extracellular matrix proteins. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[3]  Aaron R Wheeler,et al.  Hydrogel discs for digital microfluidics. , 2012, Biomicrofluidics.

[4]  R. Bleackley,et al.  Cytotoxic T lymphocytes: all roads lead to death , 2002, Nature Reviews Immunology.

[5]  Aaron R Wheeler,et al.  A microfluidic platform for complete mammalian cell culture. , 2010, Lab on a chip.

[6]  Jagannathan Rajagopalan,et al.  MEMS sensors and microsystems for cell mechanobiology , 2011, Journal of micromechanics and microengineering : structures, devices, and systems.

[7]  Ting-Hsuan Chen,et al.  Selective Wettability Assisted Nanoliter Sample Generation via Electrowetting-Based Transportation , 2007 .

[8]  D. Beebe,et al.  Control mechanism of an organic self-regulating microfluidic system , 2003 .

[9]  J. Lammertyn,et al.  Biofunctionalization of electrowetting-on-dielectric digital microfluidic chips for miniaturized cell-based applications. , 2011, Lab on a chip.

[10]  M. D. Chamberlain,et al.  A digital microfluidic method for multiplexed cell-based apoptosis assays. , 2012, Lab on a chip.

[11]  D. Beebe,et al.  Controlled microfluidic interfaces , 2005, Nature.

[12]  M. Yamada,et al.  Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel. , 2004, Analytical chemistry.

[13]  The Hitchhiker's Guide to the Inner (Cellular) Galaxies: Cytology, Cytometry, Cytomics, Cellomics and Kinomics. , 2005, Microscopy and Microanalysis.

[14]  C. Simmons,et al.  A digital microfluidic platform for primary cell culture and analysis. , 2012, Lab on a chip.

[15]  J. Lammertyn,et al.  A versatile electrowetting-based digital microfluidic platform for quantitative homogeneous and heterogeneous bio-assays , 2011 .

[16]  A. Wheeler,et al.  Virtual microwells for digital microfluidic reagent dispensing and cell culture. , 2012, Lab on a chip.

[17]  C. Batt,et al.  Hydrodynamic focusing with a microlithographic manifold: controlling the vertical position of a focused sample , 2009 .

[18]  Vijay Srinivasan,et al.  Applications of electrowetting-based digital microfluidics in clinical diagnostics , 2011, Expert review of molecular diagnostics.

[19]  A. Wheeler,et al.  A digital microfluidic method for dried blood spot analysis. , 2011, Lab on a chip.

[20]  Shilpa Sivashankar,et al.  Enhanced cell viability and cell adhesion using low conductivity medium for negative dielectrophoretic cell patterning , 2010, Biotechnology journal.

[21]  Philippe Dubois,et al.  Actuation potentials and capillary forces in electrowetting based microsystems , 2007 .

[22]  Jack Zhou,et al.  Chemical and Biological Applications of Digital-Microfluidic Devices , 2007, IEEE Design & Test of Computers.

[23]  K. Jensen,et al.  Cells on chips , 2006, Nature.

[24]  Elaine F Reed,et al.  Specific binding and magnetic concentration of CD8+ T-lymphocytes on electrowetting-on-dielectric platform. , 2010, Biomicrofluidics.

[25]  Mehmet Toner,et al.  Blood-on-a-chip. , 2005, Annual review of biomedical engineering.

[26]  R. Tompkins,et al.  Continuous inertial focusing, ordering, and separation of particles in microchannels , 2007, Proceedings of the National Academy of Sciences.

[27]  Daniel T. Chiu,et al.  Microfluidic systems: High radial acceleration in microvortices , 2003, Nature.

[28]  J. Sturm,et al.  Continuous Particle Separation Through Deterministic Lateral Displacement , 2004, Science.