Increased antigen responsiveness of naive CD8 T cells exposed to IL‐7 and IL‐21 is associated with decreased CD5 expression

[1]  Upendra K. Kar,et al.  IL-7 Promotes CXCR3 Ligand-Dependent T Cell Antitumor Reactivity in Lung Cancer1 , 2009, The Journal of Immunology.

[2]  A. Sharpe,et al.  SnapShot: B7/CD28 Costimulation , 2009, Cell.

[3]  T. Mak,et al.  Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies , 2009, Nature Medicine.

[4]  T. Hirano,et al.  Hepatic interleukin-7 expression regulates T cell responses. , 2009, Immunity.

[5]  G. Koretzky,et al.  T cell activation. , 2009, Annual review of immunology.

[6]  M. Michaud,et al.  Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice , 2009, Diabetes.

[7]  L. Hennighausen,et al.  Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells , 2009, Nature Immunology.

[8]  J. Sprent,et al.  Homeostasis of naive and memory T cells. , 2008, Immunity.

[9]  W. Leonard,et al.  IL-21 signaling is critical for the development of type I diabetes in the NOD mouse , 2008, Proceedings of the National Academy of Sciences.

[10]  N. Sarvetnick,et al.  IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms , 2008, PloS one.

[11]  P. Reichardt,et al.  TCR Antagonism by Peptide Requires High TCR Expression1 , 2008, The Journal of Immunology.

[12]  D. Venzon,et al.  Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets , 2008, The Journal of experimental medicine.

[13]  Alexandre Cloutier,et al.  IL-6, in Synergy with IL-7 or IL-15, Stimulates TCR-Independent Proliferation and Functional Differentiation of CD8+ T Lymphocytes1 , 2008, The Journal of Immunology.

[14]  F. Ponchel,et al.  Interleukin-7 in rheumatoid arthritis. , 2008, Rheumatology.

[15]  Y. Iwakura,et al.  IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+ T cells , 2008, The Journal of experimental medicine.

[16]  Tak W. Mak,et al.  CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity , 2008, Proceedings of the National Academy of Sciences.

[17]  A. Singer,et al.  'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR , 2007, Nature Immunology.

[18]  C. Liu,et al.  IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells. , 2007, International immunology.

[19]  B. Hinz,et al.  Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells , 2007, Nature Immunology.

[20]  H. Harbo,et al.  Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis , 2007, Nature Genetics.

[21]  S. Ramanathan,et al.  Regulation of IL-21 signaling by suppressor of cytokine signaling-1 (SOCS1) in CD8(+) T lymphocytes. , 2007, Cellular signalling.

[22]  Marjolein J. W. de Bruijn,et al.  GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development , 2007, European journal of immunology.

[23]  Mark J. Smyth,et al.  IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production1 , 2007, The Journal of Immunology.

[24]  R. Mazzucchelli,et al.  Interleukin-7 receptor expression: intelligent design , 2007, Nature Reviews Immunology.

[25]  S. Akira,et al.  IL-21–induced Bɛ cell apoptosis mediated by natural killer T cells suppresses IgE responses , 2006, The Journal of experimental medicine.

[26]  T. Hirano,et al.  Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7–dependent homeostatic proliferation of CD4+ T cells , 2006, The Journal of experimental medicine.

[27]  Robyn L Stanfield,et al.  How TCRs bind MHCs, peptides, and coreceptors. , 2006, Annual review of immunology.

[28]  W. Ellmeier,et al.  CD8 T Cell Sensory Adaptation Dependent on TCR Avidity for Self-Antigens1 , 2005, The Journal of Immunology.

[29]  T. Fry,et al.  The Many Faces of IL-7: From Lymphopoiesis to Peripheral T Cell Maintenance , 2005, The Journal of Immunology.

[30]  J. Berzofsky,et al.  Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function , 2005, The Journal of experimental medicine.

[31]  A. Singer,et al.  Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. , 2004, Immunity.

[32]  N. Sarvetnick,et al.  Homeostatic Expansion of T Cells during Immune Insufficiency Generates Autoimmunity , 2004, Cell.

[33]  C. Shachaf,et al.  The E47 transcription factor negatively regulates CD5 expression during thymocyte development. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[34]  C. Surh,et al.  A Role for TCR Affinity in Regulating Naive T Cell Homeostasis 1 , 2004, The Journal of Immunology.

[35]  J. Curtsinger,et al.  CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine 1 , 2003, The Journal of Immunology.

[36]  Paula Kavathas,et al.  Interplay between TCR Affinity and Necessity of Coreceptor Ligation: High-Affinity Peptide-MHC/TCR Interaction Overcomes Lack of CD8 Engagement 1 , 2003, The Journal of Immunology.

[37]  Susan M. Kaech,et al.  TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells1 , 2003, The Journal of Immunology.

[38]  I. Jang,et al.  Negative regulation of TCR signaling and T-cell activation by selective protein degradation. , 2003, Current opinion in immunology.

[39]  R. Zamoyska,et al.  TCR and IL-7 Receptor Signals Can Operate Independently or Synergize to Promote Lymphopenia-Induced Expansion of Naive T Cells1 , 2002, The Journal of Immunology.

[40]  Stephen C. Jameson,et al.  Maintaining the norm: T-cell homeostasis , 2002, Nature Reviews Immunology.

[41]  T. Hirano,et al.  IL-6 in autoimmune disease and chronic inflammatory proliferative disease. , 2002, Cytokine & growth factor reviews.

[42]  C. Benoist,et al.  Cytokine Requirements for Acute and Basal Homeostatic Proliferation of Naive and Memory CD8+ T Cells , 2002, The Journal of experimental medicine.

[43]  J. Sprent,et al.  Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8+ T Cells , 2002, The Journal of experimental medicine.

[44]  Andrew Gibson,et al.  AP2 Adaptor Complex-Dependent Internalization of CD5: Differential Regulation in T and B Cells1 , 2002, The Journal of Immunology.

[45]  T. Fry,et al.  Interleukin-7: from bench to clinic. , 2002, Blood.

[46]  L. Glimcher,et al.  Transcription: tantalizing times for T cells. , 2002, Cell.

[47]  C. Thompson,et al.  IL-7 Enhances the Survival and Maintains the Size of Naive T Cells1 , 2001, The Journal of Immunology.

[48]  J. Whitton,et al.  Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR , 2001, Nature Immunology.

[49]  Richard Murray,et al.  IL-7 is critical for homeostatic proliferation and survival of naïve T cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[50]  L. Herzenberg,et al.  The regulation of CD5 expression in murine T cells , 2001, BMC Molecular Biology.

[51]  L. Geiselhart,et al.  IL-7 Administration Alters the CD4:CD8 Ratio, Increases T Cell Numbers, and Increases T Cell Function in the Absence of Activation1 , 2001, The Journal of Immunology.

[52]  T. Fry,et al.  IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation. , 2001, Blood.

[53]  S. Jameson,et al.  Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo , 2000, Nature Immunology.

[54]  Henrique Veiga-Fernandes,et al.  Response of naïve and memory CD8+ T cells to antigen stimulation in vivo , 2000, Nature Immunology.

[55]  H. Nishina,et al.  Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b , 2000, Nature.

[56]  H. Makino,et al.  Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis. , 1999, Arthritis and rheumatism.

[57]  D. Bowtell,et al.  Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes. , 1999, Journal of immunology.

[58]  S. Kanner,et al.  CD5 Negatively Regulates the T-Cell Antigen Receptor Signal Transduction Pathway: Involvement of SH2-Containing Phosphotyrosine Phosphatase SHP-1 , 1999, Molecular and Cellular Biology.

[59]  K. Muegge,et al.  Interleukin-7: physiological roles and mechanisms of action. , 1999, Cytokine & growth factor reviews.

[60]  A. Grinberg,et al.  CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity , 1998, The Journal of experimental medicine.

[61]  L. Samelson,et al.  LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation , 1998, Cell.

[62]  G. Friedman,et al.  Interleukin-7-enhanced cytotoxic T lymphocyte activity after viral infection in marrow transplanted mice , 1997, Bone Marrow Transplantation.

[63]  K. Rajewsky,et al.  A role for CD5 in TCR-mediated signal transduction and thymocyte selection. , 1995, Science.

[64]  K. Ariizumi,et al.  IFN-gamma-dependent IL-7 gene regulation in keratinocytes. , 1995, Journal of immunology.

[65]  S. Burdach,et al.  Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine , 1995, The Journal of experimental medicine.

[66]  C. Ware,et al.  Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice , 1994, The Journal of experimental medicine.

[67]  T. Back,et al.  Administration of recombinant human IL-7 to mice alters the composition of B-lineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases. , 1994, Journal of immunology.

[68]  D. Longo,et al.  Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts. , 1993, The Journal of clinical investigation.

[69]  D. Cantrell,et al.  T-cell activation. , 1992, Trends in cell biology.

[70]  Robert E. Miller,et al.  In vivo evaluation of the effects of interleukins 2, 4 and 7 on enhancing the immunotherapeutic efficacy of anti‐tumor cytotoxic T lymphocytes , 1991, European journal of immunology.

[71]  S. Rosenberg,et al.  Interleukin 7 generates antitumor cytotoxic T lymphocytes against murine sarcomas with efficacy in cellular adoptive immunotherapy , 1991, The Journal of experimental medicine.

[72]  H. Pircher,et al.  Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice , 1991, Cell.

[73]  M. Richter,et al.  Cytokine synergy in antigen-independent activation and priming of naive CD8+ T lymphocytes. , 2009, Critical reviews in immunology.

[74]  T. Watts,et al.  TNF/TNFR family members in costimulation of T cell responses. , 2005, Annual review of immunology.

[75]  M. V. D. van den Brink,et al.  IL-7 and IL-15: therapeutic cytokines for immunodeficiency. , 2005, Trends in immunology.

[76]  B. Rocha,et al.  High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division , 2004, Nature Immunology.

[77]  Andrew Gibson,et al.  AP 2 Adaptor Complex-Dependent Internalization of CD 5 : Differential Regulation in T and B Cells 1 , 2002 .

[78]  C. Murre,et al.  E protein function in lymphocyte development. , 2002, Annual review of immunology.

[79]  L. Herzenberg,et al.  The regulation of CD 5 expression in murine T cells , 2001 .

[80]  L. Butterfield,et al.  Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication. , 2000, Human gene therapy.