G protein-coupled receptors control NMDARs and metaplasticity in the hippocampus.

[1]  H. V. Van Tol,et al.  D2‐class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet‐derived growth factor receptor‐dependent , 2006, Journal of neurochemistry.

[2]  David G Standaert,et al.  Dopamine D1 Activation Potentiates Striatal NMDA Receptors by Tyrosine Phosphorylation-Dependent Subunit Trafficking , 2006, The Journal of Neuroscience.

[3]  Rafael Yuste,et al.  Protein kinase A regulates calcium permeability of NMDA receptors , 2006, Nature Neuroscience.

[4]  Xian-Min Yu.  The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity , 2006, Molecular Neurobiology.

[5]  J. Roder,et al.  Modulation of NMDA Receptors by Pituitary Adenylate Cyclase Activating Peptide in CA1 Neurons Requires Gαq, Protein Kinase C, and Activation of Src , 2005, The Journal of Neuroscience.

[6]  R. Blitzer,et al.  Long-Term Potentiation: Mechanisms of Induction and Maintenance , 2005, Science's STKE.

[7]  Tomoyuki Takahashi.  Postsynaptic receptor mechanisms underlying developmental speeding of synaptic transmission , 2005, Neuroscience Research.

[8]  V. Pawlak,et al.  Lack of NMDA Receptor Subtype Selectivity for Hippocampal Long-Term Potentiation , 2005, The Journal of Neuroscience.

[9]  Wade Morishita,et al.  Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses , 2005, Nature Neuroscience.

[10]  Eric Gouaux,et al.  Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors , 2005, Neuron.

[11]  R. Roskoski,et al.  Src kinase regulation by phosphorylation and dephosphorylation. , 2005, Biochemical and biophysical research communications.

[12]  Michael D. Ehlers,et al.  Homeostatic plasticity and NMDA receptor trafficking , 2005, Trends in Neurosciences.

[13]  P. Paoletti,et al.  Modulation of Triheteromeric NMDA Receptors by N-Terminal Domain Ligands , 2005, Neuron.

[14]  Stephen F Traynelis,et al.  Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles , 2005, The Journal of physiology.

[15]  R. Roskoski,et al.  Src protein-tyrosine kinase structure and regulation. , 2004, Biochemical and biophysical research communications.

[16]  F. Lee,et al.  Direct interactions between NMDA and D1 receptors: a tale of tails. , 2004, Biochemical Society transactions.

[17]  P. Castillo,et al.  Endocannabinoid-Mediated Metaplasticity in the Hippocampus , 2004, Neuron.

[18]  G. Collingridge,et al.  Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression , 2004, The Journal of Neuroscience.

[19]  K. Tang,et al.  Spatial and Temporal Regulation of RACK1 Function and N-methyl-D-aspartate Receptor Activity through WD40 Motif-mediated Dimerization* , 2004, Journal of Biological Chemistry.

[20]  M. Sheng,et al.  Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity , 2004, Science.

[21]  R. Petralia,et al.  Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[22]  H. Hashimoto,et al.  [Altered higher brain function in PACAP-knockout mice]. , 2004, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

[23]  Michael W. Salter,et al.  Src kinases: a hub for NMDA receptor regulation , 2004, Nature Reviews Neuroscience.

[24]  M. Tymianski,et al.  Molecular mechanisms underlying specificity of excitotoxic signaling in neurons. , 2004, Current molecular medicine.

[25]  M. Mayer,et al.  Structure and function of glutamate receptor ion channels. , 2004, Annual review of physiology.

[26]  B. H. Shah,et al.  GPCR-mediated transactivation of RTKs in the CNS: mechanisms and consequences , 2004, Trends in Neurosciences.

[27]  Angus C Nairn,et al.  DARPP-32: an integrator of neurotransmission. , 2004, Annual review of pharmacology and toxicology.

[28]  John D. Scott,et al.  AKAP mediated signal transduction. , 2003, Annual review of pharmacology and toxicology.

[29]  H. Hashimoto,et al.  Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice , 2003, Neuroreport.

[30]  M. Salter,et al.  Interactions between Src family protein tyrosine kinases and PSD-95 , 2003, Neuropharmacology.

[31]  R. Nicoll,et al.  AMPA Receptor Trafficking at Excitatory Synapses , 2003, Neuron.

[32]  J. Roder,et al.  Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons* , 2003, Journal of Biological Chemistry.

[33]  Sheraz Yaqub,et al.  Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain. , 2003, The Biochemical journal.

[34]  K. Taskén,et al.  Protein Kinase A Intersects Src Signaling in Membrane Microdomains* , 2003, The Journal of Biological Chemistry.

[35]  Richard G M Morris,et al.  Introduction. Long-term potentiation and structure of the issue. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[36]  D. Ron,et al.  Pituitary Adenylate Cyclase-activating Polypeptide (PACAP(1–38)) Enhances N-Methyl-d-aspartate Receptor Function and Brain-derived Neurotrophic Factor Expression via RACK1* , 2003, The Journal of Biological Chemistry.

[37]  S. Ferguson.  Receptor tyrosine kinase transactivation: fine-tuning synaptic transmission , 2003, Trends in Neurosciences.

[38]  M. Weller,et al.  Signaling from cAMP/PKA to MAPK and synaptic plasticity , 2003, Molecular Neurobiology.

[39]  H. Bading,et al.  The Yin and Yang of NMDA receptor signalling , 2003, Trends in Neurosciences.

[40]  R. Harte,et al.  RACK1: a novel substrate for the Src protein-tyrosine kinase , 2002, Oncogene.

[41]  Yitao Liu,et al.  Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions , 2002, Science.

[42]  Hitoshi Hashimoto,et al.  Higher brain functions of PACAP and a homologous Drosophila memory gene amnesiac: insights from knockouts and mutants. , 2002, Biochemical and biophysical research communications.

[43]  B. Orser,et al.  A D2 Class Dopamine Receptor Transactivates a Receptor Tyrosine Kinase to Inhibit NMDA Receptor Transmission , 2002, Neuron.

[44]  L. Raymond,et al.  Differential regulation of synaptic and extra-synaptic NMDA receptors , 2002, Nature Neuroscience.

[45]  M. Johnson,et al.  Additional signals from VPAC/PAC family receptors. , 2002, Biochemical Society transactions.

[46]  M. Behrens,et al.  Metabotropic Glutamate Receptor 1-Induced Upregulation of NMDA Receptor Current: Mediation through the Pyk2/Src-Family Kinase Pathway in Cortical Neurons , 2002, The Journal of Neuroscience.

[47]  P. Chazot,et al.  Immunohistochemical localization of N-methyl-D-aspartate receptor subunits in the adult murine hippocampal formation: evidence for a unique role of the NR2D subunit. , 2002, Brain research. Molecular brain research.

[48]  H. Bading,et al.  Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways , 2002, Nature Neuroscience.

[49]  G. Westbrook,et al.  Mobile NMDA Receptors at Hippocampal Synapses , 2002, Neuron.

[50]  A. Bonci,et al.  NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1 , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[51]  U. Gerber.  G-protein-coupled receptors, tyrosine kinases and neurotransmission , 2002, Neuropharmacology.

[52]  G. Westbrook,et al.  Intracellular domains of NR2 alter calcium-dependent inactivation of N-methyl-D-aspartate receptors. , 2002, Molecular pharmacology.

[53]  M P Walsh,et al.  Regulation of NMDA Receptor Activity by F-Actin and Myosin Light Chain Kinase , 2001, The Journal of Neuroscience.

[54]  Z. Bashir,et al.  Long-term depression: a cascade of induction and expression mechanisms , 2001, Progress in Neurobiology.

[55]  J. Macdonald,et al.  Convergence of PKC-dependent kinase signal cascades on NMDA receptors. , 2001, Current drug targets.

[56]  M. Bennett,et al.  Activation of Metabotropic Glutamate Receptor 1 Accelerates NMDA Receptor Trafficking , 2001, The Journal of Neuroscience.

[57]  A. Konnerth,et al.  Impairment of Mossy Fiber Long-Term Potentiation and Associative Learning in Pituitary Adenylate Cyclase Activating Polypeptide Type I Receptor-Deficient Mice , 2001, The Journal of Neuroscience.

[58]  S. Shioda,et al.  PACAP activates PKA, PKC and Ca2+ signaling cascades in rat neuroepithelial cells , 2001, Peptides.

[59]  C. Cartwright,et al.  The Interaction of Src and RACK1 Is Enhanced by Activation of Protein Kinase C and Tyrosine Phosphorylation of RACK1* , 2001, The Journal of Biological Chemistry.

[60]  M. Bennett,et al.  mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C , 2001, Neuropharmacology.

[61]  P. Nguyen.  CREB and the enhancement of long-term memory , 2001, Trends in Neurosciences.

[62]  H. Bading,et al.  A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication , 2001, Nature Neuroscience.

[63]  M. Salter,et al.  NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity , 2001, Current Opinion in Neurobiology.

[64]  J. Sweatt,et al.  Leitmotifs in the biochemistry of LTP induction: amplification, integration and coordination , 2001, Journal of neurochemistry.

[65]  F. Nicoletti,et al.  Molecular determinants of metabotropic glutamate receptor signaling. , 2001, Trends in pharmacological sciences.

[66]  J. Roder,et al.  CAKβ/Pyk2 Kinase Is a Signaling Link for Induction of Long-Term Potentiation in CA1 Hippocampus , 2001, Neuron.

[67]  Wei-Yang Lu,et al.  Activation of Synaptic NMDA Receptors Induces Membrane Insertion of New AMPA Receptors and LTP in Cultured Hippocampal Neurons , 2001, Neuron.

[68]  M. Umemiya,et al.  A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs , 2001, The Journal of Neuroscience.

[69]  S. Shioda,et al.  Distribution of PACAP Receptor and Its Splice Variants in the Rat Brain by in Situ RT‐PCR , 2000, Annals of the New York Academy of Sciences.

[70]  S. Shioda,et al.  Ontogeny of PACAP Receptor and Its Splice Variants in the Rat Brain , 2000, Annals of the New York Academy of Sciences.

[71]  J. Lisman,et al.  Inhibition of the cAMP Pathway Decreases Early Long-Term Potentiation at CA1 Hippocampal Synapses , 2000, The Journal of Neuroscience.

[72]  B. Orser,et al.  In CA1 Pyramidal Neurons of the Hippocampus Protein Kinase C Regulates Calcium-Dependent Inactivation of NMDA Receptors , 2000, The Journal of Neuroscience.

[73]  F. Stephenson,et al.  Immunohistochemical localization of N-methyl-d-aspartate receptor NR1, NR2A, NR2B and NR2C/D subunits in the adult mammalian cerebellum , 2000, Neuroscience Letters.

[74]  J. Scott,et al.  A-kinase anchoring proteins: protein kinase A and beyond. , 2000, Current opinion in cell biology.

[75]  T. Soderling,et al.  Postsynaptic protein phosphorylation and LTP , 2000, Trends in Neurosciences.

[76]  J. Macdonald,et al.  Distinct Roles of Synaptic and Extrasynaptic NMDA Receptors in Excitotoxicity , 2000, The Journal of Neuroscience.

[77]  B. Gähwiler,et al.  G-protein-independent signaling mediated by metabotropic glutamate receptors , 1999, Nature Neuroscience.

[78]  J. Roder,et al.  Src Potentiation of NMDA Receptors in Hippocampal and Spinal Neurons Is Not Mediated by Reducing Zinc Inhibition , 1999, The Journal of Neuroscience.

[79]  B. Orser,et al.  Platelet-derived Growth Factor Receptor-induced Feed-forward Inhibition of Excitatory Transmission between Hippocampal Pyramidal Neurons* , 1999, The Journal of Biological Chemistry.

[80]  P. Chazot,et al.  Biochemical Evidence for the Co-association of ThreeN-Methyl-d-aspartate (NMDA) R2 Subunits in Recombinant NMDA Receptors* , 1999, The Journal of Biological Chemistry.

[81]  L. Raymond,et al.  Subtype-Dependence of NMDA Receptor Channel Open Probability , 1999, The Journal of Neuroscience.

[82]  M. Sheng,et al.  Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. , 1999, Science.

[83]  J. Sanes,et al.  Can molecules explain long-term potentiation? , 1999, Nature Neuroscience.

[84]  R. Lefkowitz,et al.  Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade , 1999, The Journal of Biological Chemistry.

[85]  Wei Yang Lu,et al.  G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors , 1999, Nature Neuroscience.

[86]  R. Dingledine,et al.  The glutamate receptor ion channels. , 1999, Pharmacological reviews.

[87]  N. Takei,et al.  Distribution of pituitary adenylate cyclase activating polypeptide mRNA in the developing rat brain. , 1999, Brain research. Molecular brain research.

[88]  Xian-Min Yu,et al.  Gain control of NMDA-receptor currents by intracellular sodium , 1998, Nature.

[89]  B. Orser,et al.  Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. , 1998, Molecular pharmacology.

[90]  S. Shioda,et al.  PACAP Protects Hippocampal Neurons against Apoptosis: Involvement of JNK/SAPK Signaling Pathway a , 1998, Annals of the New York Academy of Sciences.

[91]  Douglas W. Yu,et al.  Beauty Is in the Eye of the Beholder , 2010, Phunny Stuph.

[92]  S. Shenolikar,et al.  Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. , 1998, Science.

[93]  C. Cartwright,et al.  RACK1, a Receptor for Activated C Kinase and a Homolog of the β Subunit of G Proteins, Inhibits Activity of Src Tyrosine Kinases and Growth of NIH 3T3 Cells , 1998, Molecular and Cellular Biology.

[94]  H. Hashimoto,et al.  Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene. , 1998, Gene.

[95]  J. Roder,et al.  Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. , 1998, Science.

[96]  Robert J. Lefkowitz,et al.  Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A , 1997, Nature.

[97]  J. David Sweatt,et al.  A Requirement for the Mitogen-activated Protein Kinase Cascade in Hippocampal Long Term Potentiation* , 1997, The Journal of Biological Chemistry.

[98]  G. Westbrook,et al.  Cytoskeletal interactions with glutamate receptors at central synapses. , 1997, Society of General Physiologists series.

[99]  E. Kandel,et al.  Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory , 1997, Cell.

[100]  Xian-Min Yu,et al.  NMDA Channel Regulation by Channel-Associated Protein Tyrosine Kinase Src , 1997, Science.

[101]  G. Westbrook,et al.  Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific. , 1996, Molecular pharmacology.

[102]  T. Dunwiddie,et al.  Platelet-derived Growth Factor Induces a Long-term Inhibition of N-Methyl-D-aspartate Receptor Function* , 1996, The Journal of Biological Chemistry.

[103]  M. Bear,et al.  Metaplasticity: the plasticity of synaptic plasticity , 1996, Trends in Neurosciences.

[104]  C. Jahr,et al.  β-Adrenergic Regulation of Synaptic NMDA Receptors by cAMP-Dependent Protein Kinase , 1996, Neuron.

[105]  C. McBain,et al.  N-methyl-D-aspartic acid receptor structure and function. , 1994, Physiological reviews.

[106]  B. Orser,et al.  Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A , 1994, Nature.

[107]  A. Arimura,et al.  Purification and characterization of the receptor for pituitary adenylate cyclase-activating polypeptide. , 1993, The Journal of biological chemistry.

[108]  L. Langeberg,et al.  A-kinase-anchoring proteins , 1993, Journal of Cell Science.

[109]  Christian Rosenmund,et al.  Rundown of N‐methyl‐D‐aspartate channels during whole‐cell recording in rat hippocampal neurons: role of Ca2+ and ATP. , 1993, The Journal of physiology.

[110]  Laurent Journot,et al.  Differential signal transduction by five splice variants of the PACAP receptor , 1993, Nature.

[111]  Christian Rosenmund,et al.  Calcium-induced actin depolymerization reduces NMDA channel activity , 1993, Neuron.

[112]  Christian Rosenmund,et al.  Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[113]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[114]  C. Jahr,et al.  Synaptic excitation mediated by glutamate-gated ion channels , 1992, Current Opinion in Neurobiology.

[115]  B. Sakmann,et al.  Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit , 1992, Neuron.

[116]  P. Greengard,et al.  Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons , 1991, Science.

[117]  N. Minamino,et al.  Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). , 1990, Biochemical and biophysical research communications.

[118]  G. Collingridge,et al.  Low-frequency activation of the NMDA receptor system can prevent the induction of LTP , 1989, Neuroscience Letters.

[119]  M. Tymianski,et al.  Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death , 2007, Molecular Neurobiology.

[120]  S. Heximer.  RGS2-mediated regulation of Gqalpha. , 2004, Methods in enzymology.

[121]  Alison L. Barth,et al.  A developmental switch in the signaling cascades for LTP induction , 2003, Nature Neuroscience.

[122]  J. Macdonald,et al.  Signaling molecules and receptor transduction cascades that regulate NMDA receptor-mediated synaptic transmission. , 2003, International review of neurobiology.

[123]  D. Mochly‐Rosen,et al.  Anchoring proteins for protein kinase C: a means for isozyme selectivity. , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[124]  D. Brautigan,et al.  Phosphatases as partners in signaling networks. , 1997, Advances in second messenger and phosphoprotein research.

[125]  Christian Rosenmund,et al.  Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons. , 1995, Journal of neurophysiology.

[126]  S. Shenolikar,et al.  Protein serine/threonine phosphatases--new avenues for cell regulation. , 1994, Annual review of cell biology.