RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation
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E. Wang | Xin Chen | Xue-Ling Mao | Xiao-Long Zhou | Gui-Xin Peng | Qing-Run Li | Yating Cao | Shi-Ying Yao
[1] E. Wang,et al. Molecular basis for human mitochondrial tRNA m3C modification by alternatively spliced METTL8 , 2022, Nucleic acids research.
[2] E. Wang,et al. Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs , 2022, Nucleic acids research.
[3] D. Hassabis,et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models , 2021, Nucleic Acids Res..
[4] L. Sazanov,et al. The assembly, regulation and function of the mitochondrial respiratory chain , 2021, Nature Reviews Molecular Cell Biology.
[5] Robert W. Taylor,et al. Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease. , 2021, Human molecular genetics.
[6] Oriol Vinyals,et al. Highly accurate protein structure prediction with AlphaFold , 2021, Nature.
[7] E. Wang,et al. The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases , 2021, Nucleic acids research.
[8] Feng-Ting Huang,et al. A single mutation attenuates both the transcription termination and RNA-dependent RNA polymerase activity of T7 RNA polymerase , 2021, bioRxiv.
[9] Zengming Zhang,et al. An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function , 2021, The Journal of biological chemistry.
[10] A. Gingras,et al. Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. , 2020, Molecular cell.
[11] Y. Arava,et al. Localization and RNA Binding of Mitochondrial Aminoacyl tRNA Synthetases , 2020, Genes.
[12] E. Wang,et al. Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNALys , 2020, Science China Life Sciences.
[13] E. Wang,et al. Molecular basis for t6A modification in human mitochondria , 2020, Nucleic acids research.
[14] Sunghoon Kim,et al. Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase. , 2019, Journal of molecular biology.
[15] Do Young Hyeon,et al. Evolution of the multi-tRNA synthetase complex and its role in cancer , 2019, The Journal of Biological Chemistry.
[16] E. Wang,et al. The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase , 2019, Nucleic acids research.
[17] F. Hensen,et al. Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB , 2019, Nucleic acids research.
[18] Robert W. Taylor,et al. Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy , 2018, Human molecular genetics.
[19] A. Munnich,et al. Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations , 2018, The Journal of Biological Chemistry.
[20] M. Poutanen,et al. Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria , 2017, Nucleic acids research.
[21] S. Pearce,et al. Regulation of Mammalian Mitochondrial Gene Expression: Recent Advances , 2017, Trends in biochemical sciences.
[22] E. Westhof,et al. Recent Advances in Mitochondrial Aminoacyl-tRNA Synthetases and Disease. , 2017, Trends in molecular medicine.
[23] O. Poch,et al. MiSynPat: An integrated knowledge base linking clinical, genetic, and structural data for disease‐causing mutations in human mitochondrial aminoacyl‐tRNA synthetases , 2017, Human mutation.
[24] L. Kuhn,et al. Two proteomic methodologies for defining N-termini of mature human mitochondrial aminoacyl-tRNA synthetases. , 2017, Methods.
[25] Alexis A. Jourdain,et al. The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules* , 2017, The Journal of Biological Chemistry.
[26] E. Shoubridge,et al. A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability , 2017, EMBO reports.
[27] L. Bottolo,et al. Wars2 is a determinant of angiogenesis , 2016, Nature Communications.
[28] Alexis A. Jourdain,et al. Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expression , 2016, The Journal of cell biology.
[29] G. Eriani,et al. A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects* , 2016, The Journal of Biological Chemistry.
[30] Sunghoon Kim,et al. Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains* , 2015, The Journal of Biological Chemistry.
[31] S. Jakobs,et al. Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid , 2015, Proceedings of the National Academy of Sciences.
[32] M. Wang,et al. Degenerate Connective Polypeptide 1 (CP1) Domain from Human Mitochondrial Leucyl-tRNA Synthetase* , 2015, The Journal of Biological Chemistry.
[33] Alexis A. Jourdain,et al. A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function. , 2015, Cell reports.
[34] E. Shoubridge,et al. Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis. , 2015, Cell reports.
[35] A. Barrientos,et al. The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly. , 2015, Cell reports.
[36] Myung Hee Kim,et al. Structure of the ArgRS–GlnRS–AIMP1 complex and its implications for mammalian translation , 2014, Proceedings of the National Academy of Sciences.
[37] Alexis A. Jourdain,et al. A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression , 2014, Human molecular genetics.
[38] W. Gong,et al. Crystal structure of E. coli arginyl-tRNA synthetase and ligand binding studies revealed key residues in arginine recognition , 2014, Protein & Cell.
[39] D. Bogenhagen,et al. Mitochondrial Ribosomal RNA (rRNA) Methyltransferase Family Members Are Positioned to Modify Nascent rRNA in Foci near the Mitochondrial DNA Nucleoid* , 2013, The Journal of Biological Chemistry.
[40] E. Shoubridge,et al. The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression. , 2013, Cell metabolism.
[41] Alexis A. Jourdain,et al. GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules , 2013, Cell metabolism.
[42] Paul Schimmel,et al. Essential nontranslational functions of tRNA synthetases. , 2013, Nature chemical biology.
[43] C. Florentz,et al. Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways. , 2013, The Biochemical journal.
[44] Sunghoon Kim,et al. Structural switch of lysyl-tRNA synthetase between translation and transcription. , 2013, Molecular cell.
[45] B. Lorber,et al. Thermodynamic properties distinguish human mitochondrial aspartyl-tRNA synthetase from bacterial homolog with same 3D architecture , 2012, Nucleic acids research.
[46] P. Stepien,et al. Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci , 2012, Nucleic acids research.
[47] E. Shoubridge,et al. A novel mutation in YARS2 causes myopathy with lactic acidosis and sideroblastic anemia , 2012, Human mutation.
[48] M. Mirande,et al. Activation of human mitochondrial lysyl-tRNA synthetase upon maturation of its premitochondrial precursor. , 2012, Biochemistry.
[49] N. Kessler,et al. Crystal structure of human mitochondrial PheRS complexed with tRNA(Phe) in the active "open" state. , 2011, Journal of molecular biology.
[50] Takeo Suzuki,et al. Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases. , 2011, Annual review of genetics.
[51] P. Stepien,et al. Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs , 2011, RNA biology.
[52] P. Schimmel,et al. Functional expansion of human tRNA synthetases achieved by structural inventions , 2010, FEBS letters.
[53] T. Katoh,et al. Biogenesis of glutaminyl-mt tRNAGln in human mitochondria , 2009, Proceedings of the National Academy of Sciences.
[54] K. Bennett,et al. RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme , 2008, Cell.
[55] E. Green,et al. The role of aminoacyl-tRNA synthetases in genetic diseases. , 2008, Annual review of genomics and human genetics.
[56] M. Ibba,et al. Aminoacyl-tRNA synthetase complexes: molecular multitasking revealed. , 2008, FEMS microbiology reviews.
[57] M. Ibba,et al. Structural and functional mapping of the archaeal multi‐aminoacyl‐tRNA synthetase complex , 2008, FEBS letters.
[58] D. Rousseau,et al. The Layered Structure of Human Mitochondrial DNA Nucleoids* , 2008, Journal of Biological Chemistry.
[59] B. Lorber,et al. Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features. , 2007, Structure.
[60] Hubert Dominique Becker,et al. The transamidosome: a dynamic ribonucleoprotein particle dedicated to prokaryotic tRNA-dependent asparagine biosynthesis. , 2007, Molecular cell.
[61] Xiang-Lei Yang,et al. Long-range structural effects of a Charcot–Marie–Tooth disease-causing mutation in human glycyl-tRNA synthetase , 2007, Proceedings of the National Academy of Sciences.
[62] S. Ackerman,et al. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration , 2006, Nature.
[63] D. Chan. Mitochondria: Dynamic Organelles in Disease, Aging, and Development , 2006, Cell.
[64] M. Ibba,et al. Loss of Editing Activity during the Evolution of Mitochondrial Phenylalanyl-tRNA Synthetase* , 2005, Journal of Biological Chemistry.
[65] D. Wallace. A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine , 2005, Annual review of genetics.
[66] K. Musier-Forsyth,et al. Cys-tRNAPro Editing by Haemophilus influenzae YbaK via a Novel Synthetase·YbaK·tRNA Ternary Complex* , 2005, Journal of Biological Chemistry.
[67] Tsutomu Suzuki,et al. Dual‐mode recognition of noncanonical tRNAsSer by seryl‐tRNA synthetase in mammalian mitochondria , 2005, The EMBO journal.
[68] C. Florentz,et al. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. , 2005, Biochemistry.
[69] S. Kelley,et al. An aminoacyl-tRNA synthetase with a defunct editing site. , 2005, Biochemistry.
[70] B. Crane,et al. An unusual tryptophanyl tRNA synthetase interacts with nitric oxide synthase in Deinococcus radiodurans. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[71] Hiroshi Kimura,et al. The functional organization of mitochondrial genomes in human cells , 2004, BMC Biology.
[72] E. Wang,et al. Human mitochondrial leucyl-tRNA synthetase with high activity produced from Escherichia coli. , 2003, Protein expression and purification.
[73] M. Mirande,et al. The N-terminal Domain of Mammalian Lysyl-tRNA Synthetase Is a Functional tRNA-binding Domain* , 2002, The Journal of Biological Chemistry.
[74] E. Hurt,et al. The intracellular location of two aminoacyl‐tRNA synthetases depends on complex formation with Arc1p , 2001, The EMBO journal.
[75] M. Ryan,et al. Translocation of Proteins into Mitochondria , 2001, IUBMB life.
[76] E. Tolkunova,et al. The Human Lysyl-tRNA Synthetase Gene Encodes Both the Cytoplasmic and Mitochondrial Enzymes by Means of an Unusual Alternative Splicing of the Primary Transcript* , 2000, The Journal of Biological Chemistry.
[77] Dino Moras,et al. tRNA aminoacylation by arginyl‐tRNA synthetase: induced conformations during substrates binding , 2000, The EMBO journal.
[78] R. Jørgensen,et al. Identification and Characterization of Human Mitochondrial Tryptophanyl-tRNA Synthetase* , 2000, The Journal of Biological Chemistry.
[79] S. Rho,et al. Genetic dissection of protein-protein interactions in multi-tRNA synthetase complex. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[80] J. Williams,et al. Complex organisation of the 5'-end of the human glycine tRNA synthetase gene. , 1998, Gene.
[81] P Vincens,et al. Computational method to predict mitochondrially imported proteins and their targeting sequences. , 1996, European journal of biochemistry.
[82] M. Mirande,et al. The multienzyme complex containing nine aminoacyl-tRNA synthetases is ubiquitous from Drosophila to mammals. , 1994, Biochimica et biophysica acta.
[83] Olivier Poch,et al. Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs , 1990, Nature.
[84] M. Deutscher,et al. Existence of two forms of rat liver arginyl-tRNA synthetase suggests channeling of aminoacyl-tRNA for protein synthesis. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[85] F. Sanger,et al. Sequence and organization of the human mitochondrial genome , 1981, Nature.