Honokiol is a FOXM1 antagonist

[1]  R. Orlowski,et al.  Proteasome inhibitors in cancer therapy , 2017, Nature Reviews Clinical Oncology.

[2]  A. Gartel,et al.  A Novel Function of Molecular Chaperone HSP70 , 2015, The Journal of Biological Chemistry.

[3]  R. Chapple,et al.  AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow. , 2015, Cell stem cell.

[4]  J. Arbiser,et al.  Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer , 2015, Oncotarget.

[5]  Ash A. Alizadeh,et al.  Abstract PR09: The prognostic landscape of genes and infiltrating immune cells across human cancers , 2015 .

[6]  Dean P. Jones,et al.  Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial SIRT3 , 2015, Nature Communications.

[7]  Giovanni Marsico,et al.  Small molecule inhibition of FOXM1: How to bring a novel compound into genomic context , 2014, Genomics data.

[8]  M. Medvedovic,et al.  SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene , 2014, PLoS genetics.

[9]  J. Arbiser,et al.  Honokiol inhibits androgen receptor activity in prostate cancer cells , 2014, The Prostate.

[10]  A. Gartel,et al.  ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors. , 2013, The Biochemical journal.

[11]  S. Katiyar,et al.  Honokiol Inhibits Non-Small Cell Lung Cancer Cell Migration by Targeting PGE2-Mediated Activation of β-Catenin Signaling , 2013, PloS one.

[12]  A. Gartel,et al.  Targeting FOXM1 in cancer. , 2013, Biochemical pharmacology.

[13]  A. Gartel,et al.  FOX(M1) News—It Is Cancer , 2013, Molecular Cancer Therapeutics.

[14]  B. Fuchs,et al.  Antimetastatic activity of honokiol in osteosarcoma , 2012, Cancer.

[15]  A. Gartel,et al.  The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA , 2011, Oncotarget.

[16]  S. Arora,et al.  Honokiol Arrests Cell Cycle, Induces Apoptosis, and Potentiates the Cytotoxic Effect of Gemcitabine in Human Pancreatic Cancer Cells , 2011, PloS one.

[17]  William F. Richter,et al.  Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets , 2010, Journal of visualized experiments : JoVE.

[18]  A. Gartel,et al.  FoxM1 Is a General Target for Proteasome Inhibitors , 2009, PloS one.

[19]  A. Gartel,et al.  A novel mode of FoxM1 regulation: Positive auto-regulatory loop , 2009, Cell cycle.

[20]  A. Gartel,et al.  Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells , 2009, PloS one.

[21]  D. Bar-Sagi,et al.  Honokiol Suppresses Survival Signals Mediated by Ras-Dependent Phospholipase D Activity in Human Cancer Cells , 2008, Clinical Cancer Research.

[22]  Lily Yang,et al.  Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo. , 2008, The Journal of investigative dermatology.

[23]  A. Gartel,et al.  Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1. , 2006, Cancer research.

[24]  B. Aggarwal,et al.  Honokiol Potentiates Apoptosis, Suppresses Osteoclastogenesis, and Inhibits Invasion through Modulation of Nuclear Factor-κB Activation Pathway , 2006, Molecular Cancer Research.

[25]  K. Anderson,et al.  Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis. , 2004, Blood.

[26]  J. Arbiser,et al.  The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells. , 2004, Blood.

[27]  A. Datta,et al.  Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. , 2004, Genes & development.

[28]  Robert H. Costa,et al.  Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators , 2004, Molecular and Cellular Biology.

[29]  P. M. Campbell,et al.  Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo* , 2003, Journal of Biological Chemistry.

[30]  H. Itokawa,et al.  [Studies on the components of Magnolia obovata Thunb. II. On the components of the methanol extract of the bark]. , 1973, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[31]  Y. Oshika,et al.  P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo. , 1996, British Journal of Cancer.