Intellectual stability in children with unilateral brain lesions

In this paper we report on the longitudinal stability of IQ in 26 children with unilateral left (LL N = 18) or right (RL N = 8) hemisphere damage. Results revealed (i) normal or near normal levels of intellectual performance in both LL and RL groups, and, (ii) hemispheric differences in the level and stability of intellectual performance. RL children achieved lower IQ scores than LL children and were more likely to decrease in VIQ over time. Cross-sectional analyses revealed a tendency for injury sustained earlier (e.g. during the first 5 years of age), rather than later in development to be associated with lower IQ scores.

[1]  E. Goldberg,et al.  Hemisphere differences in the acquisition and use of descriptive systems , 1981, Brain and Language.

[2]  D. Wechsler Manual for the Wechsler Adult Intelligence Scale. , 1955 .

[3]  R. Thatcher,et al.  Human cerebral hemispheres develop at different rates and ages. , 1987, Science.

[4]  A. Papanicolaou,et al.  Probe-evoked potential findings following unilateral left-hemisphere lesions in children. , 1990, Archives of neurology.

[5]  S. Dikmen,et al.  The Effect of Early Versus Late Onset of Major Motor Epilepsy upon Cognitive‐Intellectual Performance , 1975, Epilepsia.

[6]  P. Huttenlocher,et al.  The effects of developmental factors on IQ in hemiplegic children , 1990, Neuropsychologia.

[7]  D. O. Hebb,et al.  The effect of early and late brain injury upon test scores, and the nature of adult intelligence. , 1942 .

[8]  S. F. Witelson,et al.  Left hemisphere specialization for language in the newborn. Neuroanatomical evidence of asymmetry. , 1973, Brain : a journal of neurology.

[9]  David Wechsler,et al.  Manual for the Wechsler intelligence scale for children , 1974 .

[10]  B. Woods The restricted effects of right-hemisphere lesions after age one; Wechsler test data , 1980, Neuropsychologia.

[11]  Alan Leviton,et al.  The Developing human brain: Growth and epidemiologic neuropathology , 1983 .

[12]  H. Lansdell Verbal and nonverbal factors in right-hemisphere speech: relation to early neurological history. , 1969, Journal of comparative and physiological psychology.

[13]  D. Aram,et al.  Differential effects of early hemisphere damage on lexical comprehension and production , 1993 .

[14]  D. Wechsler Manual for the Wechsler preschool and primary scale of intelligence , 1967 .

[15]  J. Fletcher,et al.  Behavioral changes after closed head injury in children. , 1990, Journal of consulting and clinical psychology.

[16]  M Dennis,et al.  The intelligence of hydrocephalic children. , 1981, Archives of neurology.

[17]  Taylor Hg,et al.  Intellectual, Neuropsychological, and Achievement Outcomes in Children Six to Eight Years After Recovery from Haemophilus influenzae Meningitis , 1984 .

[18]  D. Riva,et al.  Late effects of unilateral brain lesions sustained before and after age one , 1986, Neuropsychologia.

[19]  Teuber Hl,et al.  Early onset of complementary specialization of cerebral hemispheres in man. , 1973 .

[20]  Diane Koch,et al.  Differential effects of congenital left and right brain injury on intelligence , 1989, Brain and Cognition.

[21]  Dorothy M. Aram,et al.  Language ability in right and left hemiplegic children , 1981, Brain and Language.

[22]  J. Fletcher,et al.  Neurobehavioral effects of central nervous system prophylactic treatment of cancer in children. , 1988, Journal of clinical and experimental neuropsychology.

[23]  H. Teuber,et al.  Behaviour after Cerebral Lesions in Children and Adults , 1962, Developmental medicine and child neurology.

[24]  M. Kennard CORTICAL REORGANIZATION OF MOTOR FUNCTION: STUDIES ON SERIES OF MONKEYS OF VARIOUS AGES FROM INFANCY TO MATURITY , 1942 .

[25]  Goldman-Rakic Ps Developmental determinants of cortical plasticity. , 1972 .

[26]  I. James-Roberts A reinterpretation of hemispherectomy data without functional plasticity of the brain I. Intellectual function , 1981, Brain and Language.

[27]  D. Aram,et al.  Cognitive profiles of children with early onset of unilateral lesions , 1986 .

[28]  N. Geschwind,et al.  Human Brain: Left-Right Asymmetries in Temporal Speech Region , 1968, Science.

[29]  M. Corballis,et al.  On the biological basis of human laterality: I. Evidence for a maturational left–right gradient , 1978, Behavioral and Brain Sciences.

[30]  P. Huttenlocher,et al.  FACTORS AFFECTING COGNITIVE FUNCTIONING OF HEMIPLEGIC CHILDREN , 1987, Developmental medicine and child neurology.

[31]  T. Frumkes Temporal summation in frogs and men , 1979, Behavioral and Brain Sciences.

[32]  F. Vargha-Khadem,et al.  Aphasia and handedness in relation to hemispheric side, age at injury and severity of cerebral lesion during childhood. , 1985, Brain : a journal of neurology.

[33]  D. Crowell,et al.  Unilateral Cortical Activity in Newborn Humans: An Early Index of Cerebral Dominance? , 1973, Science.

[34]  S. Corkin,et al.  Penetrating head injury in young adulthood exacerbates cognitive decline in later years , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[35]  W D Obrist,et al.  Differences in the distribution of gray and white matter in human cerebral hemispheres. , 1980, Science.