The role of dietary plant and animal protein intakes on mitigating sarcopenia risk

Purpose of review To highlight contemporary findings comparing the digestibility of animal and plant proteins, their stimulatory effects on muscle protein synthesis, and associations with sarcopenia. Recent findings Animal proteins are more digestible than plant proteins, resulting in greater amino acid availability and stimulation of muscle protein synthesis. However, isolated plant proteins, plant protein blends, and modified plant proteins enriched with indispensable amino acids can elicit comparable digestion and absorption kinetics to animal proteins. More research is needed to determine whether these modified plant protein sources can effectively mitigate sarcopenia risk. Summary Both animal and plant protein foods can be incorporated into a healthful eating plan that limits risk of age-related diseases, such as sarcopenia. Humans eat food rather than isolated nutrients; as such, considering the context of the overall diet and its impact on health, instead of solely focusing on individual nutrients in isolation, is important.

[1]  L. V. van Loon,et al.  Potato Protein Ingestion Increases Muscle Protein Synthesis Rates at Rest and during Recovery from Exercise in Humans , 2022, Medicine and science in sports and exercise.

[2]  S. Brennan,et al.  The effect of animal versus plant protein on muscle mass, muscle strength, physical performance and sarcopenia in adults: protocol for a systematic review , 2022, Systematic Reviews.

[3]  Xinglian Xu,et al.  Real meat and plant-based meat analogues have different in vitro protein digestibility properties. , 2022, Food chemistry.

[4]  J. Erdman,et al.  Perspective: Soy-based Meat and Dairy Alternatives, Despite Classification as Ultra-processed Foods, Deliver High-quality Nutrition on Par with Unprocessed or Minimally Processed Animal-based Counterparts , 2022, Advances in nutrition.

[5]  F. Hu,et al.  Protein intake and risk of frailty among older women in the Nurses' Health Study , 2022, Journal of cachexia, sarcopenia and muscle.

[6]  L. D. de Groot,et al.  Perspective: Vegan Diets for Older Adults? A Perspective On the Potential Impact On Muscle Mass and Strength , 2022, Advances in nutrition.

[7]  L. D. de Groot,et al.  Ingestion of an ample amount of meat substitute based on a lysine-enriched, plant-based protein blend stimulates postprandial muscle protein synthesis to a similar extent as an isonitrogenous amount of chicken in healthy, young men , 2021, British Journal of Nutrition.

[8]  S. Walrand,et al.  Pea Proteins Have Anabolic Effects Comparable to Milk Proteins on Whole Body Protein Retention and Muscle Protein Metabolism in Old Rats , 2021, Nutrients.

[9]  R. Benamouzig,et al.  Real ileal amino acid digestibility of pea protein compared to casein in healthy humans, a randomized trial. , 2021, The American journal of clinical nutrition.

[10]  H. Stein,et al.  Digestible indispensable amino acid score (DIAAS) is greater in animal-based burgers than in plant-based burgers if determined in pigs , 2021, European Journal of Nutrition.

[11]  L. V. van Loon,et al.  The Anabolic Response to Plant-Based Protein Ingestion , 2021, Sports Medicine.

[12]  S. Pasiakos,et al.  Physiological Limitations of Protein Foods Ounce Equivalents and the Underappreciated Role of Essential Amino Acid Density in Healthy Dietary Patterns. , 2021, The Journal of nutrition.

[13]  W. Willett,et al.  Red meat consumption and risk of frailty in older women , 2021, Journal of cachexia, sarcopenia and muscle.

[14]  N. Shivappa,et al.  The role of diet quality and dietary patterns in predicting muscle mass and function in men over a 15-year period , 2021, Osteoporosis International.

[15]  S. Gil,et al.  High-Protein Plant-Based Diet Versus a Protein-Matched Omnivorous Diet to Support Resistance Training Adaptations: A Comparison Between Habitual Vegans and Omnivores , 2021, Sports Medicine.

[16]  David M. Goldman,et al.  Limitations with the Digestible Indispensable Amino Acid Score (DIAAS) with Special Attention to Plant-Based Diets: a Review , 2021, Current Nutrition Reports.

[17]  A. McCarthy,et al.  Dietary protein considerations for muscle protein synthesis and muscle mass preservation in older adults , 2020, Nutrition Research Reviews.

[18]  M. Singer,et al.  Animal protein intake reduces risk of functional impairment and strength loss in older adults. , 2020, Clinical nutrition.

[19]  M. Dirks,et al.  Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans , 2020, The Journal of nutrition.

[20]  K. Hackney,et al.  Protein and muscle health during aging: benefits and concerns related to animal-based protein , 2019, Animal frontiers : the review magazine of animal agriculture.

[21]  Laurent Mosoni,et al.  Postprandial whole-body protein metabolism after a meat meal is influenced by chewing efficiency in elderly subjects. , 2007, The American journal of clinical nutrition.