Development and Application of an Electrospray Ionization Ion Mobility-mass Spectrometer Using an RF Ion Funnel and Periodic-focusing Ion Guide

[1]  Danielle M. Williams,et al.  Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry. , 2013, Mass spectrometry reviews.

[2]  Shu-hua Chen,et al.  Combining chemical labeling, bottom-up and top-down ion-mobility mass spectrometry to identify metal-binding sites of partially metalated metallothionein. , 2013, Analytical chemistry.

[3]  K. Giles Travelling wave ion mobility , 2013, International Journal for Ion Mobility Spectrometry.

[4]  D. Russell,et al.  Cis-trans isomerizations of proline residues are key to bradykinin conformations. , 2013, Journal of the American Chemical Society.

[5]  Ingrid Pettersson,et al.  Traveling-wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross-sections of human insulin oligomers. , 2012, Rapid communications in mass spectrometry : RCM.

[6]  F. Calvo,et al.  Statistical Analysis of Ion Mobility Spectrometry. II. Adaptively Biased Methods and Shape Correlations , 2012, Journal of The American Society for Mass Spectrometry.

[7]  S. Valentine,et al.  Conformation types of ubiquitin [M+8H]8+ Ions from water:methanol solutions: evidence for the N and A States in aqueous solution. , 2012, The journal of physical chemistry. B.

[8]  Kyle L. Fort,et al.  Damping factor links periodic focusing and uniform field ion mobility for accurate determination of collision cross sections. , 2012, Analytical chemistry.

[9]  Y. Gao,et al.  How alkali metal ion binding alters the conformation preferences of gramicidin A: a molecular dynamics and ion mobility study. , 2012, The journal of physical chemistry. A.

[10]  T. Wyttenbach,et al.  Structural stability from solution to the gas phase: native solution structure of ubiquitin survives analysis in a solvent-free ion mobility-mass spectrometry environment. , 2011, The journal of physical chemistry. B.

[11]  David H Russell,et al.  Number of solution states of bradykinin from ion mobility and mass spectrometry measurements. , 2011, Journal of the American Chemical Society.

[12]  K. Stanković,et al.  Initiation and progress of breakdown in the range to the left of the paschen minimum , 2011, IEEE Transactions on Dielectrics and Electrical Insulation.

[13]  T. Benter,et al.  Numerical Simulation and Experimental Validation of the Three-Dimensional Flow Field and Relative Analyte Concentration Distribution in an Atmospheric Pressure Ion Source , 2011, Journal of the American Society for Mass Spectrometry.

[14]  P. Barran,et al.  Evidence for α-helices in the gas phase: a case study using Melittin from honey bee venom. , 2011, The Analyst.

[15]  D. Barkley,et al.  The Onset of Turbulence in Pipe Flow , 2011, Science.

[16]  E. De Pauw,et al.  Effective temperature of ions in traveling wave ion mobility spectrometry. , 2011, Analytical chemistry.

[17]  P. Dugourd,et al.  Coupling infrared multiphoton dissociation spectroscopy, mass-spectrometry and ion mobility spectrometry for the determination of structures of angiotensin II cations , 2011 .

[18]  Carl Caleman,et al.  Proteins, lipids, and water in the gas phase. , 2011, Macromolecular bioscience.

[19]  I. Campuzano,et al.  A method for direct measurement of ion mobilities using a travelling wave ion guide , 2010 .

[20]  C. Robinson,et al.  Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology. , 2010, Analytical chemistry.

[21]  D. Russell,et al.  Gas-phase ion dynamics in a periodic-focusing DC ion guide , 2010 .

[22]  Jody C. May,et al.  Dual source ion mobility-mass spectrometer for direct comparison of electrospray ionization and MALDI collision cross section measurements. , 2010, Analytical chemistry.

[23]  C. Pace,et al.  Factors that influence helical preferences for singly charged gas-phase peptide ions: the effects of multiple potential charge-carrying sites. , 2010, The journal of physical chemistry. B.

[24]  O. Raether,et al.  Applying a dynamic method to the measurement of ion mobility , 2009, Journal of the American Society for Mass Spectrometry.

[25]  M. Bowers,et al.  A new, higher resolution, ion mobility mass spectrometer , 2009 .

[26]  F. Fernandez-Lima,et al.  Ion mobility-mass spectrometer interface for collisional activation of mobility separated ions. , 2009, Analytical chemistry.

[27]  W. D. Laidig,et al.  Three-dimensional structure of bradykinin in SDS micelles. Study using nuclear magnetic resonance, distance geometry, and restrained molecular mechanics and dynamics. , 2009, International journal of peptide and protein research.

[28]  Richard D. Smith,et al.  Fundamentals of traveling wave ion mobility spectrometry. , 2008, Analytical chemistry.

[29]  D. J. Douglas,et al.  Conformations of gas-phase ions of ubiquitin, cytochrome c, apomyoglobin, and β-lactoglobulin produced from two different solution conformations , 2008, Journal of the American Society for Mass Spectrometry.

[30]  Brian C. Bohrer,et al.  Biomolecule analysis by ion mobility spectrometry. , 2008, Annual review of analytical chemistry.

[31]  Brandon T Ruotolo,et al.  Ion mobility–mass spectrometry analysis of large protein complexes , 2008, Nature Protocols.

[32]  Erin Shammel Baker,et al.  Ion mobility spectrometry—mass spectrometry performance using electrodynamic ion funnels and elevated drift gas pressures , 2007, Journal of the American Society for Mass Spectrometry.

[33]  Ryan T Kelly,et al.  Array of chemically etched fused-silica emitters for improving the sensitivity and quantitation of electrospray ionization mass spectrometry. , 2007, Analytical chemistry.

[34]  O. García-Valladares,et al.  Numerical simulation of non-adiabatic capillary tubes considering metastable region. Part I: Mathematical formulation and numerical model , 2007 .

[35]  Xiao-Guang Wu Ion dynamics in non-perfect quadrupole traps , 2007 .

[36]  J. Bruce,et al.  Design and performance of an atmospheric pressure ion mobility Fourier transform ion cyclotron resonance mass spectrometer. , 2007, Rapid communications in mass spectrometry : RCM.

[37]  Erin Shammel Baker,et al.  Optimization of algorithms for ion mobility calculations. , 2007, The journal of physical chemistry. A.

[38]  D. Clemmer,et al.  Resolution and structural transitions of elongated states of ubiquitin , 2007, Journal of the American Society for Mass Spectrometry.

[39]  C. Robinson,et al.  Evidence for Macromolecular Protein Rings in the Absence of Bulk Water , 2005, Science.

[40]  A. Ross,et al.  Speciation of cyclo(Pro-Gly)3 and its divalent metal-ion complexes by electrospray ionization mass spectrometry , 2005, Journal of the American Society for Mass Spectrometry.

[41]  B. Ruotolo,et al.  The structure of gas-phase bradykinin fragment 1–5 (RPPGF) ions: An ion mobility spectrometry and H/D exchange ion-molecule reaction chemistry study , 2005, Journal of the American Society for Mass Spectrometry.

[42]  Michael A. Buschbach,et al.  High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces. , 2005, Analytical chemistry.

[43]  B. Ruotolo,et al.  An electrostatic focusing ion guide for ion mobility-mass spectrometry , 2004 .

[44]  Roger Guevremont,et al.  High-field asymmetric waveform ion mobility spectrometry: a new tool for mass spectrometry. , 2004, Journal of chromatography. A.

[45]  R. Bateman,et al.  Applications of a travelling wave-based radio-frequency-only stacked ring ion guide. , 2004, Rapid communications in mass spectrometry : RCM.

[46]  P. Wolynes Energy landscapes and solved protein–folding problems , 2004, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[47]  I. Chernushevich,et al.  Collisional cooling of large ions in electrospray mass spectrometry. , 2004, Analytical chemistry.

[48]  A. Stretton,et al.  The first sequence. Fred Sanger and insulin. , 2002, Genetics.

[49]  D. Clemmer,et al.  Dissociation of different conformations of ubiquitin ions , 2002, Journal of the American Society for Mass Spectrometry.

[50]  Guido F Verbeck,et al.  A fundamental introduction to ion mobility mass spectrometry applied to the analysis of biomolecules. , 2002, Journal of Biomolecular Techniques.

[51]  J. Lisy Atom, Molecule, and Cluster Beams , 2001 .

[52]  D. Barnett,et al.  Gas-phase conformers of the [M + 2H](2+) ion of bradykinin investigated by combining high-field asymmetric waveform ion mobility spectrometry, hydrogen/deuterium exchange, and energy-loss measurements. , 2001, Rapid communications in mass spectrometry : RCM.

[53]  R. Smith,et al.  A multicapillary inlet jet disruption electrodynamic ion funnel interface for improved sensitivity using atmospheric pressure ion sources. , 2001, Analytical chemistry.

[54]  A. E. Counterman,et al.  Collision-induced dissociation of mobility-separated ions using an orifice-skimmer cone at the back of a drift tube. , 2001, Analytical chemistry.

[55]  D. Dahl simion for the personal computer in reflection , 2000 .

[56]  J. Baumbach,et al.  Comparison of electric fields within drift tubes for ion mobility spectrometry , 2000 .

[57]  D. Baker,et al.  A surprising simplicity to protein folding , 2000, Nature.

[58]  T. Wyttenbach,et al.  Conformations of biopolymers in the gas phase: a new mass spectrometric method 2 2 Dedicated to Bob , 2000 .

[59]  David E. Clemmer,et al.  Influence of solvent composition and capillary temperature on the conformations of electrosprayed ions: unfolding of compact ubiquitin conformers from pseudonative and denatured solutions , 1999 .

[60]  Roger Guevremont,et al.  Atmospheric pressure ion focusing in a high-field asymmetric waveform ion mobility spectrometer , 1999 .

[61]  S. Valentine,et al.  ESI/ion trap/ion mobility/time-of-flight mass spectrometry for rapid and sensitive analysis of biomolecular mixtures. , 1999, Analytical chemistry.

[62]  G A Anderson,et al.  An ion funnel interface for improved ion focusing and sensitivity using electrospray ionization mass spectrometry. , 1998, Analytical chemistry.

[63]  S. Valentine,et al.  High-order structure and dissociation of gaseous peptide aggregates that are hidden in mass spectra , 1998, Journal of the American Society for Mass Spectrometry.

[64]  D. Muddiman,et al.  Nanoelectrospray mass spectrometry using non‐metalized, tapered (50 → 10 μm) fused‐silica capillaries , 1998 .

[65]  Scott A. Shaffer,et al.  A novel ion funnel for focusing ions at elevated pressure using electrospray ionization mass spectrometry , 1997 .

[66]  David E. Clemmer,et al.  Conformer-dependent proton-transfer reactions of ubiquitin ions , 1997 .

[67]  B. Thomson,et al.  A segmented radiofrequency-only quadrupole collision cell for measurements of ion collision cross section on a triple quadrupole mass spectrometer , 1997 .

[68]  David E. Clemmer,et al.  Ion Mobility Measurements and their Applications to Clusters and Biomolecules , 1997 .

[69]  M. Jarrold,et al.  PROTEIN STRUCTURE IN VACUO : GAS-PHASE CONFORMATIONS OF BPTI AND CYTOCHROME C , 1997 .

[70]  T. Wyttenbach,et al.  Effect of the long-range potential on ion mobility measurements , 1997 .

[71]  H. Hill,et al.  Fourier transform electrospray ion mobility spectrometry , 1996 .

[72]  F. Hirayama,et al.  Mass Spectroscopic Evidence on Inhibiting Effect of Maltosyl–β‐Cyclodextrin on Insulin Self‐association , 1996 .

[73]  A. Shvartsburg,et al.  An exact hard-spheres scattering model for the mobilities of polyatomic ions , 1996 .

[74]  George C. Schatz,et al.  Structural Information from Ion Mobility Measurements: Effects of the Long-Range Potential , 1996 .

[75]  Michael T. Bowers,et al.  Gas-Phase Conformation of Biological Molecules: Bradykinin , 1996 .

[76]  F. McLafferty,et al.  Mass Spectrometry: Recent Advances and Future Directions , 1996 .

[77]  David E. Clemmer,et al.  NAKED PROTEIN CONFORMATIONS : CYTOCHROME C IN THE GAS PHASE , 1995 .

[78]  Christopher Jones Circular dichroism: Principles and applications , 1995 .

[79]  Ching Wu,et al.  Measuring the Resolving Power of Ion Mobility Spectrometers , 1994 .

[80]  D. J. Douglas,et al.  Collision cross sections for protein ions , 1993, Journal of the American Society for Mass Spectrometry.

[81]  M. Bowers,et al.  Gas-Phase Ion Chromatography: Transition Metal State Selection and Carbon Cluster Formation , 1993, Science.

[82]  D. J. Douglas,et al.  Collisional focusing effects in radio frequency quadrupoles , 1992, Journal of the American Society for Mass Spectrometry.

[83]  P. Armentrout,et al.  The charge-transfer reaction N+2 (X, ν = 0) + Ar → Ar+ + N2 from thermal to 20 eV c.m. , 1991 .

[84]  M. Mann,et al.  Electrospray ionization for mass spectrometry of large biomolecules. , 1989, Science.

[85]  C. Bugg,et al.  Structure of ubiquitin refined at 1.8 A resolution. , 1987, Journal of molecular biology.

[86]  R. Cooks,et al.  Internal energy distributions of isolated ions after activation by various methods , 1987 .

[87]  J. Fenn,et al.  Electrospray interface for liquid chromatographs and mass spectrometers. , 1985, Analytical chemistry.

[88]  F. J. Knorr,et al.  Fourier transform ion mobility spectrometry. , 1985, Analytical chemistry.

[89]  C. C. Davis,et al.  Building Scientific Apparatus , 1983 .

[90]  R. D. Shannon Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides , 1976 .

[91]  E. A. Mason,et al.  Theory of plasma chromatography/gaseous electrophoresis. Review , 1975 .

[92]  C. Anfinsen Principles that govern the folding of protein chains. , 1973, Science.

[93]  N. Ling,et al.  Primary structure of somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[94]  James B. Anderson,et al.  Velocity Distributions in Molecular Beams from Nozzle Sources , 1965 .

[95]  T. Milne,et al.  Mass Spectrometric Detection of Polymers in Supersonic Molecular Beams , 1963 .

[96]  Edward A. Mason,et al.  Mobility of gaseous lons in weak electric fields , 1958 .

[97]  I. Mclaren,et al.  TIME-OF-FLIGHT MASS SPECTROMETER WITH IMPROVED RESOLUTION , 1955 .

[98]  Norris E. Bradbury,et al.  Absolute Values of the Electron Mobility in Hydrogen , 1936 .

[99]  B. Thomson,et al.  Atmospheric pressure ion sources. , 2009, Mass spectrometry reviews.

[100]  Roberto Ierusalimschy,et al.  Exploring Lua for Concurrent Programming , 2008, J. Univers. Comput. Sci..

[101]  A G Cochran,et al.  Tryptophan zippers: stable, monomeric beta -hairpins. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[102]  M. Jarrold,et al.  Peptides and proteins in the vapor phase. , 2000, Annual review of physical chemistry.

[103]  S. Guan,et al.  Stacked-ring electrostatic ion guide , 1996, Journal of the American Society for Mass Spectrometry.

[104]  Martin F. Jarrold,et al.  DRIFT TUBE STUDIES OF ATOMIC CLUSTERS , 1995 .

[105]  Z. Warsi Fluid dynamics: theoretical and computational approaches , 1993 .

[106]  H H Hill,et al.  Ion mobility spectrometry. , 1990, Analytical chemistry.

[107]  R. C. Weast CRC Handbook of Chemistry and Physics , 1973 .

[108]  S. A. Schaaf Rarefied Gas Dynamics , 1969 .

[109]  H. Dehmelt,et al.  Radiofrequency Spectroscopy of Stored Ions I: Storage , 1968 .