Evaluation of Hydra HALT-1 as a toxin moiety for recombinant immunotoxin
暂无分享,去创建一个
J. Hwang | L. L. In | W. F. Jiemy | Hong Xi Sha | L. Hiew
[1] J. Hwang,et al. Cytotoxic and apoptosis-inducing effects of wildtype and mutated Hydra actinoporin-like toxin 1 (HALT-1) on various cancer cell lines , 2019, PeerJ.
[2] Adam C. Labonte,et al. Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus , 2018, PloS one.
[3] J. Kamps,et al. Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: Current status and future prospects. , 2018, Autoimmunity reviews.
[4] U. Ros,et al. Sticholysin II-mediated cytotoxicity involves the activation of regulated intracellular responses that anticipates cell death. , 2018, Biochimie.
[5] Publisher's Note , 2018, Anaesthesia.
[6] G. Anderluh,et al. Pore-forming toxins in Cnidaria. , 2017, Seminars in cell & developmental biology.
[7] T. Thepen,et al. CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases , 2017, Biomedicines.
[8] P. A. Valiente,et al. Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone , 2017, Biophysical Reviews.
[9] F. G. van der Goot,et al. Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux. , 2017, Biochimica et biophysica acta. Biomembranes.
[10] A. Zernecke,et al. Macrophages in vascular inflammation and atherosclerosis , 2017, Pflügers Archiv - European Journal of Physiology.
[11] R. Fischer,et al. Fully human MAP‐fusion protein selectively targets and eliminates proliferating CD64+ M1 macrophages , 2016, Immunology and cell biology.
[12] G. Anderluh,et al. Pore formation by actinoporins, cytolysins from sea anemones. , 2016, Biochimica et biophysica acta.
[13] A. Lurati,et al. The macrophages in rheumatic diseases , 2016, Journal of inflammation research.
[14] R. Fischer,et al. Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies , 2015, mAbs.
[15] R. Robison,et al. Macrophage Polarization and Its Role in Cancer , 2015 .
[16] J. Hwang,et al. Mutagenesis and Functional Analysis of the Pore-Forming Toxin HALT-1 from Hydra magnipapillata , 2015, Toxins.
[17] A. Reiss,et al. Polarization of Human THP-1 Macrophages: Link between Adenosine Receptors, Inflammation and Lipid Accumulation , 2014 .
[18] Eliezra Glasser,et al. Hydra actinoporin-like toxin-1, an unusual hemolysin from the nematocyst venom of Hydra magnipapillata which belongs to an extended gene family. , 2014, Toxicon : official journal of the International Society on Toxinology.
[19] G. Melmer,et al. Targeted ex vivo reduction of CD64‐positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B‐based cytolytic fusion proteins , 2014, International journal of cancer.
[20] Wei-Chiang Shen,et al. Fusion protein linkers: property, design and functionality. , 2013, Advanced drug delivery reviews.
[21] Bharat V. Adkar,et al. Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin , 2013, PloS one.
[22] Kirsten Sandvig,et al. Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro , 2013 .
[23] Veerendra Kumar,et al. Linkers in the structural biology of protein–protein interactions , 2013, Protein science : a publication of the Protein Society.
[24] S. Mayfield,et al. Production of unique immunotoxin cancer therapeutics in algal chloroplasts , 2012, Proceedings of the National Academy of Sciences.
[25] Yuhong Xiao,et al. Enzyme-linked immunosorbent assay (ELISA) and blocking with bovine serum albumin (BSA)--not all BSAs are alike. , 2012, Journal of immunological methods.
[26] Assaf Shapira,et al. Toxin-Based Therapeutic Approaches , 2010, Toxins.
[27] R. Fischer,et al. Recombinant, ETA′‐based CD64 immunotoxins: improved efficacy by increased valency, both in vitro and in vivo in a chronic cutaneous inflammation model in human CD64 transgenic mice , 2010, The British journal of dermatology.
[28] J. Lakey,et al. A Toxin-based Probe Reveals Cytoplasmic Exposure of Golgi Sphingomyelin* , 2010, The Journal of Biological Chemistry.
[29] R. Fischer,et al. Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes , 2008, Molecular Cancer Therapeutics.
[30] I. Pastan,et al. Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity. , 2008, Cancer research.
[31] I. Pastan,et al. Phase I Study of SS1P, a Recombinant Anti-Mesothelin Immunotoxin Given as a Bolus I.V. Infusion to Patients with Mesothelin-Expressing Mesothelioma, Ovarian, and Pancreatic Cancers , 2007, Clinical Cancer Research.
[32] M. Harmsen,et al. CD64-Directed Immunotoxin Inhibits Arthritis in a Novel CD64 Transgenic Rat Model1 , 2006, The Journal of Immunology.
[33] G. Anderluh,et al. Membrane insertion of the N-terminal α-helix of equinatoxin II, a sea anemone cytolytic toxin , 2004 .
[34] L. Roque,et al. Construction of an immunotoxin with the pore forming protein StI and ior C5, a monoclonal antibody against a colon cancer cell line. , 2004, International immunopharmacology.
[35] Regina M. Krohn,et al. Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells. , 2003, Cancer research.
[36] A. Plückthun,et al. A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[37] J. Bijlsma,et al. Selective elimination of synovial inflammatory macrophages in rheumatoid arthritis by an Fcgamma receptor I-directed immunotoxin. , 2003, Arthritis and rheumatism.
[38] V. Gabai,et al. Necrosis: a specific form of programmed cell death? , 2003, Experimental cell research.
[39] Gregor Anderluh,et al. Two-step Membrane Binding by Equinatoxin II, a Pore-forming Toxin from the Sea Anemone, Involves an Exposed Aromatic Cluster and a Flexible Helix* , 2002, The Journal of Biological Chemistry.
[40] M. Miller,et al. Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor. , 2000, Protein engineering.
[41] G. Anderluh,et al. Antiparasite activity of sea-anemone cytolysins on Giardia duodenalis and specific targeting with anti-Giardia antibodies. , 1999, International journal for parasitology.
[42] M. Hulett,et al. The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a. , 1998, Molecular immunology.
[43] R. Salmon,et al. Escherichia coli O157 serology: false‐positive ELISA results caused by human antibodies binding to bovine serum albumin , 1998, Letters in applied microbiology.
[44] B. Clark,et al. Glycerol diversifies phage repertoire selections and lowers non‐specific phage absorption , 1998, FEBS letters.
[45] J. Shaw,et al. Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins. , 1991, The Journal of biological chemistry.
[46] A. Lage,et al. A new immunotoxin built by linking a hemolytic toxin to a monoclonal antibody specific for immature T lymphocytes , 1988, International journal of cancer.
[47] 梁曉灡. Mechanism of antibody-dependent enhancement in severe acute respiratory syndrome coronavirus infection , 2012 .
[48] M. Comalada,et al. Macrophage proinflammatory activation and deactivation: a question of balance. , 2010, Advances in immunology.
[49] T. Thepen,et al. Resolution of cutaneous inflammation after local elimination of macrophages , 2000, Nature Biotechnology.