A CD4+ T cell population expanded in Lupus blood provides B cell help through IL10 and succinate

[1]  S. Rahman,et al.  IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE , 2018, Nature Communications.

[2]  Bjoern Peters,et al.  Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis , 2018, Science Immunology.

[3]  Kamil Slowikowski,et al.  Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis , 2017, Nature.

[4]  N. Huang,et al.  Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years , 2016, Current Rheumatology Reports.

[5]  V. Pascual,et al.  Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus , 2016, The Journal of experimental medicine.

[6]  P. Navas,et al.  The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency. , 2016, Cell reports.

[7]  M. Buck,et al.  T cell metabolism drives immunity , 2015, The Journal of experimental medicine.

[8]  Qing-Yu He,et al.  ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization , 2015, Bioinform..

[9]  Ivan V. Gregoretti,et al.  Diversity, cellular origin and autoreactivity of antibody-secreting cell expansions in acute Systemic Lupus Erythematosus , 2015, Nature Immunology.

[10]  H. Ueno,et al.  Pathophysiology of T follicular helper cells in humans and mice , 2015, Nature Immunology.

[11]  H. Ueno,et al.  The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells , 2014, Nature Immunology.

[12]  H. Ueno,et al.  TGF-β co-opts STAT3-STAT4 signaling to promote human T follicular helper cell differentiation , 2014, Nature Immunology.

[13]  L. O’Neill,et al.  Succinate: a metabolic signal in inflammation. , 2014, Trends in cell biology.

[14]  Björn Usadel,et al.  Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..

[15]  B. Hill,et al.  Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis , 2014, Nature Protocols.

[16]  Alessandro Sette,et al.  Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. , 2013, Immunity.

[17]  Howard Y. Chang,et al.  Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position , 2013, Nature Methods.

[18]  Liang Zheng,et al.  Succinate is an inflammatory signal that induces IL-1β through HIF-1α , 2013, Nature.

[19]  J. Licht,et al.  Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. , 2013, Immunity.

[20]  G. Tsokos,et al.  Systemic lupus erythematosus. , 2011, The New England journal of medicine.

[21]  P. Marrack,et al.  Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. , 2011, Blood.

[22]  E. Meffre,et al.  In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis , 2011, The Journal of Immunology.

[23]  H. Ueno,et al.  Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. , 2011, Immunity.

[24]  J. Peti-Peterdi High glucose and renin release: the role of succinate and GPR91. , 2010, Kidney international.

[25]  V. Pascual,et al.  TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus , 2010, Nature.

[26]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[27]  Richard Durbin,et al.  Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .

[28]  Michael P. Murphy,et al.  How mitochondria produce reactive oxygen species , 2008, The Biochemical journal.

[29]  M. Gilliet,et al.  Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases , 2008, Nature Reviews Immunology.

[30]  G. Freeman,et al.  PD-1 and its ligands in tolerance and immunity. , 2008, Annual review of immunology.

[31]  D. Jarrossay,et al.  Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells , 2007, Nature Immunology.

[32]  X. Qin,et al.  Plasmacytoid dendritic cells prime IL-10–producing T regulatory cells by inducible costimulator ligand , 2007, The Journal of experimental medicine.

[33]  F. V. van Pelt,et al.  Resazurin assay of radiation response in cultured cells. , 2005, The British journal of radiology.

[34]  D. Golenbock,et al.  Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. , 2005, The Journal of clinical investigation.

[35]  J. Moreau,et al.  Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus. , 2005, Arthritis and rheumatism.

[36]  P. Lipsky,et al.  Correlation of circulating CD27high plasma cells and disease activity in systemic lupus erythematosus , 2004, Lupus.

[37]  Lee Hebert,et al.  The classification of glomerulonephritis in systemic lupus erythematosus revisited. , 2004, Journal of the American Society of Nephrology : JASN.

[38]  Virginia Pascual,et al.  Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. , 2003, Immunity.

[39]  Yong‐jun Liu,et al.  Human plasmacytoid-derived dendritic cells and the induction of T-regulatory cells. , 2002, Human immunology.

[40]  K. Gilbert,et al.  The ability of antigen, but not interleukin‐2, to promote n‐butyrate‐induced T helper 1 cell anergy is associated with increased expression and altered association patterns of cyclin‐dependent kinase inhibitors , 2002, Immunology.

[41]  L. Adorini,et al.  Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells1 , 2001, The Journal of Immunology.

[42]  V. Pascual,et al.  Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus1 , 2001, The Journal of Immunology.

[43]  R. Coffman,et al.  Interleukin-10 and the interleukin-10 receptor. , 2001, Annual review of immunology.

[44]  D. Stewart,et al.  Expression of Nitric Oxide Synthases and Nitrotyrosine during Blood-Brain Barrier Breakdown and Repair after Cold Injury , 2001, Laboratory Investigation.

[45]  L. Glimcher,et al.  Lineage commitment in the immune system: the T helper lymphocyte grows up. , 2000, Genes & development.

[46]  M. Hochberg,et al.  Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. , 1997, Arthritis and rheumatism.

[47]  J. Banchereau,et al.  The Enigmatic Plasmacytoid T Cells Develop into Dendritic Cells with Interleukin (IL)-3 and CD40-Ligand , 1997, The Journal of experimental medicine.

[48]  J. Banchereau,et al.  Fas ligation induces apoptosis of CD40-activated human B lymphocytes , 1995, The Journal of experimental medicine.

[49]  J. Goust,et al.  Systemic lupus erythematosus. , 1976, Immunology series.

[50]  J. Banchereau,et al.  Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. , 1992, Proceedings of the National Academy of Sciences of the United States of America.