Réponses somesthésiques, visuelles et auditives, recueillies au niveau du cortex ⪡associatif⪢ non anesthésié

Resume Cette etude, portant sur 50 chats prepares sous ether, puis immobilises au Flaxedil, concerne les reponses ⪡ irradiees ⪢ a des stimuli somesthesiques, visuels et auditifs, que l'on peut recueillir sur les aires associatives de la convexite, gyrus lateral anterieur et suprasylvien (reponses secondaires ⪡ associatives ⪢). 1. 1. Par leur latence et leur duree, ces reponses se distinguent nettement des activites de projection primaire. Pour chaque modalite, une analyse est faite de leur repartition, assez large en general, a la surface du cortex associatif. 2. 2. Les reponses associatives se montrent d'une particuliere sensibilite aux barbituriques ainsi qu'a tout effet de depression. La narcose profonde au chloralose les amplifie par contre dans des proportions importantes. 3. 3. Des oscillations du niveau de vigilance suscitent des variations significatives de l'irradiation associative; celle-ci, absente en cas d'activation corticale d'eveil, se developpe au contraire pour un niveau inferieur de vigilance, en general concomitant d'un trace ample; elle disparaitra a nouveau lorsque l'animal dort profondement. Ces correlations ont ete confirmees sur animal normal porteur d'electrodes implantees. 4. 4. Les reponses secondaires associatives apparaissent independantes des aires de projection primaire: ni des ablations etendues ni la depression pharmacologique de ces dernieres ne les affecte irreversiblement. 5. 5. L'origine et la signification des phenomenes observes est discutee. Un parallelisme est en particulier etabli entre l'irradiation sensorielle associative obtenue sous curare et celle observee en narcose profonde au chloralose.

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