Mechanisms of monocyte recruitment and accumulation.

The involvement of the bloodborne monocyte in phenomena related to vascular interactions, including wound healing and atherosclerosis, has been well recognised for several decades. As discussed in detail in several articles in this supplement, the monocyte-derived macrophage has been implicated in multiple aspects of atherosclerotic plaque development (figure). These cells contribute to the formation of fatty streak lesions by ingesting massive amounts of lipid and thus developing into foam cells

[1]  A. Gown,et al.  Various cell types in human atherosclerotic lesions express ICAM-1. Further immunocytochemical and immunochemical studies employing monoclonal antibody 10F3. , 1992, The American journal of pathology.

[2]  A. Mantovani,et al.  Molecules involved in the adhesion and cytotoxicity of activated monocytes on endothelial cells. , 1992, Journal of immunology.

[3]  W. Buurman,et al.  Role of ELAM‐1 in Adhesion of Monocytes to Activated Human Endothelial Cells , 1992, Scandinavian journal of immunology.

[4]  R. Wallace,et al.  Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICAM-1 induction. , 1992, The American journal of physiology.

[5]  A. Mantovani,et al.  Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes. , 1992, Journal of immunology.

[6]  E. Butcher.  Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity , 1991, Cell.

[7]  A. J. Valente,et al.  Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein. , 1991, The Journal of clinical investigation.

[8]  D. Hajjar.  Warner-Lambert/Parke-Davis Award Lecture. Viral pathogenesis of atherosclerosis. Impact of molecular mimicry and viral genes. , 1991, The American journal of pathology.

[9]  T. Kuijpers,et al.  Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4. , 1991, Blood.

[10]  T. Ono,et al.  Role of inflammatory responses in initiation of atherosclerosis: effects of anti-inflammatory drugs on cuff-induced leukocyte accumulation and intimal thickening of rabbit carotid artery. , 1991, Atherosclerosis.

[11]  P. Bath,et al.  Human monocyte characteristics are altered in hypercholesterolaemia. , 1991, Atherosclerosis.

[12]  C. Gahmberg,et al.  The expression of human intercellular adhesion molecule‐2 is refractory to inflammatory cytokines , 1991, European journal of immunology.

[13]  K. Pritchard,et al.  Native low density lipoprotein. Endothelial cell recruitment of mononuclear cells. , 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

[14]  P. Libby,et al.  Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells. , 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

[15]  R. Silverstein,et al.  Identification of a monocyte receptor on herpesvirus-infected endothelial cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[16]  J. Schmee,et al.  Comparison of effects of fish oil and corn oil supplements on hyperlipidemic diet induced atherogenesis in swine. , 1991, Atherosclerosis.

[17]  P. Tarr,et al.  Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[18]  L. Needham,et al.  Structural and functional studies of the endothelial activation antigen endothelial leucocyte adhesion molecule-1 using a panel of monoclonal antibodies. , 1991, Journal of immunology.

[19]  J. Gamble,et al.  Inhibition of human monocyte adhesion by interleukin-4. , 1991, Blood.

[20]  C. Bruggeman,et al.  The effect of virus infection on the adherence of leukocytes or platelets to endothelial cells , 1991, European journal of clinical investigation.

[21]  C. Benjamin,et al.  Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1 , 1991 .

[22]  M. Cybulsky,et al.  Alternative splicing of human VCAM-1 in activated vascular endothelium. , 1991, The American journal of pathology.

[23]  R. Palmer,et al.  Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro. , 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

[24]  M. Cybulsky,et al.  Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. , 1991, Science.

[25]  F. Gaeta,et al.  ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. , 1990, Science.

[26]  B. Seed,et al.  Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells. , 1990, Science.

[27]  J. Lowe,et al.  ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA , 1990, Cell.

[28]  D. Wagner,et al.  PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15) , 1990, Cell.

[29]  S. Ogawa,et al.  Advanced protein glycosylation induces transendothelial human monocyte chemotaxis and secretion of platelet-derived growth factor: role in vascular disease of diabetes and aging. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[30]  A. Mantovani,et al.  Re-evaluation of the chemotactic activity of tumour necrosis factor for monocytes. , 1990, Immunology.

[31]  R. Ross,et al.  Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits. , 1990, Arteriosclerosis.

[32]  Timothy A. Springer,et al.  Adhesion receptors of the immune system , 1990, Nature.

[33]  A. J. Valente,et al.  Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[34]  E. Leonard,et al.  Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. , 1990, Journal of immunology.

[35]  J. Gamble,et al.  IL-3 and granulocyte-macrophage colony-stimulating factor stimulate two distinct phases of adhesion in human monocytes. , 1990, Journal of immunology.

[36]  S. Schwartz,et al.  Cell proliferation in human coronary arteries. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[37]  M. Territo,et al.  Minimally modified low density lipoprotein stimulates monocyte endothelial interactions. , 1990, The Journal of clinical investigation.

[38]  M. Elices,et al.  VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site , 1990, Cell.

[39]  B. E. Huber,et al.  3-deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells. , 1990, Journal of immunology.

[40]  R. Tizard,et al.  Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes , 1989, Cell.

[41]  Obin,et al.  Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions. , 1989, Science.

[42]  C. A. de la Motte,et al.  Role of cell surface carbohydrate moieties in monocytic cell adhesion to endothelium in vitro. , 1989, Journal of immunology.

[43]  C. A. de la Motte,et al.  Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway. , 1989, The Biochemical journal.

[44]  M. Territo,et al.  Beta-very low density lipoprotein pretreatment of endothelial monolayers increases monocyte adhesion. , 1989, Arteriosclerosis.

[45]  Michael L. Dustin,et al.  T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1 , 1989, Nature.

[46]  H. Stanton,et al.  Influence of probucol on early experimental atherogenesis in hypercholesterolemic rats. , 1989, Atherosclerosis.

[47]  P. Sims,et al.  Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. , 1989, The Journal of biological chemistry.

[48]  Michael Loran Dustin,et al.  Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1 , 1989, Nature.

[49]  E. Schmidt,et al.  Cod liver oil inhibits neutrophil and monocyte chemotaxis in healthy males. , 1989, Atherosclerosis.

[50]  W. J. Visser,et al.  Peroxidative stress and in vitro ageing of endothelial cells increases the monocyte-endothelial cell adherence in a human in vitro system. , 1989, Atherosclerosis.

[51]  B. Seed,et al.  Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. , 1989, Science.

[52]  C. V. van Boven,et al.  Virus induced adherence of monocytes to endothelial cells. , 1989, FEMS microbiology immunology.

[53]  E. Appella,et al.  Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE , 1989, FEBS letters.

[54]  B. Furie,et al.  PADGEM protein in human erythroleukemia cells. , 1989, Blood.

[55]  Gary R. Grotendorst,et al.  Platelet-derived growth factor is not chemotactic for human peripheral blood monocytes. , 1989, Experimental cell research.

[56]  G. Kaplan,et al.  The selective binding and transmigration of monocytes through the junctional complexes of human endothelium , 1988, The Journal of experimental medicine.

[57]  B. Williams,et al.  Transendothelial chemotaxis in vitro of human monocytes. , 1988, Journal of immunological methods.

[58]  F. Luscinskas,et al.  Cultured human endothelial cells stimulated with cytokines or endotoxin produce an inhibitor of leukocyte adhesion. , 1988, The Journal of clinical investigation.

[59]  A. Mantovani,et al.  Role of GM-CSF in phagocyte recruitment and regulation of c-fos protooncogene expression. , 1988, Behring Institute Mitteilungen.

[60]  D. Steinberg,et al.  Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[61]  Michael Loran Dustin,et al.  Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families , 1988, Cell.

[62]  Timothy A. Springer,et al.  Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1) , 1987, Cell.

[63]  R. Cotran,et al.  Identification of an inducible endothelial-leukocyte adhesion molecule. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[64]  T. Springer,et al.  Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. , 1987, The Journal of clinical investigation.

[65]  L M Wakefield,et al.  Transforming growth factor type beta induces monocyte chemotaxis and growth factor production. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[66]  C. Figdor,et al.  Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells. , 1987, Immunology.

[67]  D. Steinberg,et al.  Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[68]  N. Pawlowski,et al.  In vitro studies of human monocyte migration across endothelium in response to leukotriene B4 and f-Met-Leu-Phe. , 1987, The American journal of pathology.

[69]  C. Haslett,et al.  Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium. , 1987, Journal of immunology.

[70]  E. Denholm,et al.  Monocyte chemoattractants in pigeon aortic atherosclerosis. , 1987, The American journal of pathology.

[71]  P. Allavena,et al.  Chemotactic activity of human recombinant granulocyte-macrophage colony-stimulating factor. , 1987, Immunology.

[72]  R. Taylor,et al.  Endothelial cell proliferation and monocyte adhesion to atherosclerotic lesions of white carneau pigeons. , 1986, The American journal of pathology.

[73]  W. Fiers,et al.  Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. , 1986, Journal of immunology.

[74]  H. Koeffler,et al.  Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor , 1986, Nature.

[75]  Michael Loran Dustin,et al.  Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). , 1986, Journal of immunology.

[76]  M. Territo,et al.  Monocyte Chemotactic Factor Produced by Large Vessel Endothelial Cells in Vitro , 1986, Arteriosclerosis.

[77]  G. Bondjers,et al.  Regional Accumulations of T Cells, Macrophages, and Smooth Muscle Cells in the Human Atherosclerotic Plaque , 1986, Arteriosclerosis.

[78]  R. Ross.  The pathogenesis of atherosclerosis--an update. , 1986, The New England journal of medicine.

[79]  R. Schleimer,et al.  Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters. , 1986, Journal of immunology.

[80]  R. Cotran,et al.  Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. , 1985, The Journal of clinical investigation.

[81]  D. Steinberg,et al.  Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[82]  H. Waldmann,et al.  Identification of macrophages and smooth muscle cells in human atherosclerosis using monoclonal antibodies , 1985, The Journal of pathology.

[83]  H. Perez,et al.  Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg. , 1985, Journal of immunology.

[84]  D. Klurfeld,et al.  Identification of foam cells in human atherosclerotic lesions as macrophages using monoclonal antibodies. , 1985, Archives of pathology & laboratory medicine.

[85]  R. Gerrity,et al.  Control of Monocyte Recruitment by Chemotactic Factor(s) in Lesion‐Prone Areas of Swine Aorta , 1985, Arteriosclerosis.

[86]  R. McEver,et al.  A monoclonal antibody to a membrane glycoprotein binds only to activated platelets. , 1984, The Journal of biological chemistry.

[87]  B. Furie,et al.  A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets. , 1984, The Journal of biological chemistry.

[88]  R. Ross,et al.  Studies of Hypercholesterolemia in the Nonhuman Primate: II. Fatty Streak Conversion to Fibrous Plaque , 1984, Arteriosclerosis.

[89]  R. Ross,et al.  Studies of Hypercholesterolemia in the Nonhuman Primate: I. Changes that Lead to Fatty Streak Formation , 1984, Arteriosclerosis.

[90]  G. Majno,et al.  Studies on the pathogenesis of atherosclerosis. I. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats. , 1983, The American journal of pathology.

[91]  J. McDougall,et al.  Viruses in the etiology of atherosclerosis. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[92]  R. Bar-Shavit,et al.  Monocyte chemotaxis: stimulation by specific exosite region in thrombin. , 1983, Science.

[93]  R. Clark,et al.  Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes. , 1982, Journal of immunology.

[94]  R. Senior,et al.  Chemotaxis of monocytes and neutrophils to platelet-derived growth factor. , 1982, The Journal of clinical investigation.

[95]  R. Gerrity,et al.  The role of the monocyte in atherogenesis: II. Migration of foam cells from atherosclerotic lesions. , 1981, The American journal of pathology.

[96]  E. Benditt,et al.  Evidence for a monoclonal origin of human atherosclerotic plaques. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[97]  R. Snyderman,et al.  Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors. , 1972, Journal of immunology.

[98]  J L Witztum,et al.  The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis. , 1992, Annual review of medicine.

[99]  L. Needham,et al.  Cloning cell surface molecules using monoclonal antibodies , 1991 .

[100]  K. Matsushima,et al.  Properties of the novel proinflammatory supergene "intercrine" cytokine family. , 1991, Annual review of immunology.

[101]  G. Shwaery,et al.  Effects of dietary fish oil and butterfat on serum lipids and monocyte and platelet interactions with aortic endothelial cells. , 1990, Atherosclerosis.

[102]  A. Mennander,et al.  Activation of protein kinase C is crucial in the regulation of ICAM-1 expression on endothelial cells by interferon-gamma. , 1990, International immunology.

[103]  C. Figdor,et al.  Role of p150,95 in adhesion, migration, chemotaxis and phagocytosis of human monocytes , 1987, European journal of immunology.

[104]  K. Hayes,et al.  Monocyte adherence to endothelial cells in vitro is increased by beta-VLDL. , 1987, The American journal of pathology.

[105]  M. Brown,et al.  Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. , 1983, Annual review of biochemistry.

[106]  R. Gerrity.  The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. , 1981, The American journal of pathology.