Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low- And Middle-Income Countries

Madhukar Pai and colleagues discuss a framework for envisioning how point-of-care testing can be applied to infectious diseases in low- and middle-income countries.

[1]  M. Pai,et al.  Tuberculosis control: business models for the private sector. , 2012, The Lancet. Infectious diseases.

[2]  T. West,et al.  Faculty Opinions recommendation of Accuracy of rapid influenza diagnostic tests: a meta-analysis. , 2012 .

[3]  W. MacLeod,et al.  Scaling up Xpert MTB/RIF technology: the costs of laboratory- vs. clinic-based roll-out in South Africa , 2012, Tropical medicine & international health : TM & IH.

[4]  M. Schito,et al.  Perspectives on introduction and implementation of new point-of-care diagnostic tests. , 2012, The Journal of infectious diseases.

[5]  Marco Schito,et al.  Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis. , 2012, The Journal of infectious diseases.

[6]  Madhukar Pai,et al.  Which new diagnostics for tuberculosis, and when? , 2012, The Journal of infectious diseases.

[7]  Lawrence Joseph,et al.  Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: a systematic review and meta-analysis. , 2012, The Lancet. Infectious diseases.

[8]  Madhukar Pai,et al.  Why are inaccurate tuberculosis serological tests widely used in the Indian private healthcare sector? A root-cause analysis , 2012, Journal of epidemiology and global health.

[9]  K. Steingart,et al.  Widespread use of serological tests for tuberculosis: data from 22 high-burden countries , 2012, European Respiratory Journal.

[10]  J. Tibenderana,et al.  Early experiences on the feasibility, acceptability, and use of malaria rapid diagnostic tests at peripheral health centres in Uganda-insights into some barriers and facilitators , 2012, Implementation Science.

[11]  N. Engel,et al.  TB diagnostics in India: creating an ecosystem for innovation , 2012, Expert review of molecular diagnostics.

[12]  M. Pai,et al.  Point-of-care diagnostics for HIV and tuberculosis: landscape, pipeline, and unmet needs. , 2012, Discovery medicine.

[13]  Anna Vassall,et al.  Rapid Diagnosis of Tuberculosis with the Xpert MTB/RIF Assay in High Burden Countries: A Cost-Effectiveness Analysis , 2011, PLoS medicine.

[14]  S. Makombe,et al.  Stigmatising Attitudes among People Offered Home-Based HIV Testing and Counselling in Blantyre, Malawi: Construction and Analysis of a Stigma Scale , 2011, PloS one.

[15]  N. French,et al.  The Uptake and Accuracy of Oral Kits for HIV Self-Testing in High HIV Prevalence Setting: A Cross-Sectional Feasibility Study in Blantyre, Malawi , 2011, PLoS medicine.

[16]  Jocalyn Clark,et al.  Speed and Convenience Aren't Everything with Diagnostics , 2011, PLoS medicine.

[17]  K. Steingart,et al.  Serological Testing Versus Other Strategies for Diagnosis of Active Tuberculosis in India: A Cost-Effectiveness Analysis , 2011, PLoS medicine.

[18]  Didier Raoult,et al.  Revolutionizing Clinical Microbiology Laboratory Organization in Hospitals with In Situ Point-of-Care , 2011, PloS one.

[19]  Madhukar Pai,et al.  Is Scale-Up Worth It? Challenges in Economic Analysis of Diagnostic Tests for Tuberculosis , 2011, PLoS medicine.

[20]  M. Pai,et al.  Mismanagement of tuberculosis in India: Causes, consequences, and the way forward , 2011 .

[21]  C. Price Point-of-Care Testing: Care Closer to Home , 2011 .

[22]  Angelika Niemz,et al.  Point-of-care nucleic acid testing for infectious diseases. , 2011, Trends in biotechnology.

[23]  Eduardo Gotuzzo,et al.  Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study , 2011, The Lancet.

[24]  M. Pai Improving TB diagnosis: difference between knowing the path and walking the path , 2011, Expert review of molecular diagnostics.

[25]  Anjali Sharma,et al.  Patient- and delivery-level factors related to acceptance of HIV counseling and testing services among tuberculosis patients in South Africa: a qualitative study with community health workers and program managers , 2011, Implementation science : IS.

[26]  M. Bergeron,et al.  Diagnosing infections--current and anticipated technologies for point-of-care diagnostics and home-based testing. , 2010, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[27]  R. Peeling,et al.  Point-of-care tests for diagnosing infections in the developing world. , 2010, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[28]  Stanley Luchters,et al.  Barriers to HIV testing in Europe: a systematic review. , 2010, European journal of public health.

[29]  Karen Steingart,et al.  New and improved tuberculosis diagnostics: evidence, policy, practice, and impact , 2010, Current opinion in pulmonary medicine.

[30]  R. Walensky,et al.  Loss to Care and Death Before Antiretroviral Therapy in Durban, South Africa , 2009, Journal of acquired immune deficiency syndromes.

[31]  S. Kalantri,et al.  Profile of adults seeking voluntary HIV testing and counseling in rural Central India: results from a hospital-based study , 2009, AIDS care.

[32]  N. Pai,et al.  Rapid Testing at Labor and Delivery to Prevent Mother-To-Child Hiv Transmission in Developing Settings: Issues and Challenges , 2009, Women's health.

[33]  Nitika Pant Pai,et al.  Are we ready for home-based, self-testing for HIV? , 2008 .

[34]  P. Yager,et al.  Point-of-care diagnostics for global health. , 2008, Annual review of biomedical engineering.

[35]  Nitika Pant Pai,et al.  Impact of Round-the-Clock, Rapid Oral Fluid HIV Testing of Women in Labor in Rural India , 2008, PLoS medicine.

[36]  K. Mossman X Prize Foundation, Santa Monica, Calif. , 2008 .

[37]  S. Ehrmeyer,et al.  Point-of-care testing, medical error, and patient safety: a 2007 assessment , 2007, Clinical chemistry and laboratory medicine.

[38]  R. Joshi,et al.  Evaluation of Diagnostic Accuracy, Feasibility and Client Preference for Rapid Oral Fluid-Based Diagnosis of HIV Infection in Rural India , 2007, PloS one.

[39]  S. Theobald,et al.  'Lost' smear-positive pulmonary tuberculosis cases: where are they and why did we lose them? , 2005, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[40]  D. Batty Care closer to home. , 2000, Nursing standard (Royal College of Nursing (Great Britain) : 1987).

[41]  E. Hook,et al.  The rapid test paradox: when fewer cases detected lead to more cases treated: a decision analysis of tests for Chlamydia trachomatis. , 1999, Sexually transmitted diseases.

[42]  M F Burritt,et al.  Point-of-care testing. , 1995, Mayo Clinic proceedings.