Use of ketamine, xylazine, and diazepam anesthesia with retrobulbar block for phacoemulsification in dogs.

OBJECTIVE The study was undertaken to evaluate the use of ketamine, xylazine, and diazepam along with a local retrobulbar nerve block for routine phacoemulsification in the dog. Animals Ten clinically healthy mixed-breed dogs of either sex, weighing between 10 and 15 kg. PROCEDURES Ten mixed-breed dogs were selected for unilateral cataract removal by phacoemulsification. Standard preoperative preparations for cataract surgery were followed. Pre-anesthetic medication consisted of atropine sulfate (0.02 mg/kg, SC). Anesthesia was induced by xylazine HCl (1.0 mg/kg, IM) followed by ketamine (5.0 mg/kg, IM). Anesthesia was maintained subsequently with IV ketamine and diazepam to effect and depth of anesthesia was assessed clinically by pedal reflex and jaw reflex. After induction of anesthesia, a retrobulbar nerve block was performed using 2 mL of 2% lignocaine. Eye position was graded after retrobulbar block and IOP was examined preoperative, post-anesthetic, 6 h postoperative and 24 h after surgery. Phacoemulsification was performed using the phaco-chop technique and an intraocular lens was placed. Anesthetic recovery and postoperative recovery following surgery was recorded. RESULT The exposure of the globe in all the dogs was adequate; the desired central fixation of the eye was obtained and surgery could be performed uneventfully. The mean IOP recorded after induction of anesthesia was 15.75 +/- 0.82, which was not significantly (P > 0.01) different from pre-anesthetic values (14.85 +/- 0.85). CONCLUSION Phacoemulsification was successfully performed with this anesthetic regimen without encountering major intraoperative or anesthetic complications.

[1]  T. Aravindakshan,et al.  GENETIC DIVERSITY IN INDIAN GOAT BREEDS BASED ON MICROSATELLITE POLYMORPHISM , 2008 .

[2]  P. Moore,et al.  Influence of lidocaine and diazepam on peri-induction intraocular pressures in dogs anesthetized with propofol-atracurium. , 2006, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

[3]  Lesley J. Smith,et al.  Development of a retrobulbar injection technique for ocular surgery and analgesia in dogs. , 2006, Journal of the American Veterinary Medical Association.

[4]  B. Torres,et al.  Effects of ketamine, diazepam, and their combination on intraocular pressures in clinically normal dogs. , 2006, American journal of veterinary research.

[5]  P. Pascoe,et al.  Reference cardiopulmonary values in normal dogs. , 2005, Comparative medicine.

[6]  S. Kiliç,et al.  Effects of anaesthetic agents on canine ocular parameters , 2005 .

[7]  Lesley J. Smith,et al.  Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: a pilot study. , 2004, Veterinary anaesthesia and analgesia.

[8]  H. Kecova,et al.  Review Article Phacoemulsification and Intraocular Lens Implantation: Recent Trends in Cataract Surgery , 2004 .

[9]  W. Good,et al.  Ketamine anaesthesia for paediatric ophthalmology surgery , 2002, The British journal of ophthalmology.

[10]  G. Atalan,et al.  Comparative Study of Butorphanol-Ketamin HCl and Xylazine- Ketamin HCl Combinations for Their Clinical and Cardiovascular/Respiratory Effects in Healthy Dogs , 2002 .

[11]  P. Barros,et al.  Effects of two preanesthetic regimens for ophthalmic surgery on intraocular pressure and cardiovascular measurements in dogs. , 2002, Veterinary therapeutics : research in applied veterinary medicine.

[12]  L. Cullen Xylazine and medetomidine in small animals: these drugs should be used carefully. , 1999, Australian veterinary journal.

[13]  S. Hazra,et al.  Anaesthetic management in canine cataract surgery , 1999 .

[14]  P. Hellyer,et al.  Respiratory function and extraocular muscle paralysis following administration of pancuronium bromide in dogs. , 1998, Veterinary ophthalmology.

[15]  A. Cunningham,et al.  Intraocular pressure -physiology and implications for anaesthetic management , 1986, Canadian Anaesthetists' Society journal.

[16]  I. Ahlgren,et al.  Ketamine infusions: pharmacokinetics and clinical effects. , 1979, British journal of anaesthesia.

[17]  M. Pernikoff TREATMENT OF ACUTE AND CHRONIC MUSCLE SPASM WITH DIAZEPAM. , 1964, Clinical medicine.