Religiosity and major depression in adults at high risk: a ten-year prospective study.

OBJECTIVE Previously the authors found that personal importance of religion or spirituality was associated with a lower risk for major depression in a study of adults with and without a history of depression. Here the authors examine the association of personal importance of religion or spirituality with major depression in the adult offspring of the original sample using a 10-year prospective longitudinal design. METHOD Participants were 114 adult offspring of depressed and nondepressed parents, followed longitudinally. The analysis covers the period from the 10-year to the 20-year follow-up assessments. Diagnosis was assessed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version. Religiosity measures included personal importance of religion or spirituality, frequency of attendance at religious services, and denomination (all participants were Catholic or Protestant). In a logistic regression analysis, major depression at 20 years was used as the outcome measure and the three religiosity variables at 10 years as predictors. RESULTS Offspring who reported at year 10 that religion or spirituality was highly important to them had about one-fourth the risk of experiencing major depression between years 10 and 20 compared with other participants. Religious attendance and denomination did not significantly predict this outcome. The effect was most pronounced among offspring at high risk for depression by virtue of having a depressed parent; in this group, those who reported a high importance of religion or spirituality had about one-tenth the risk of experiencing major depression between years 10 and 20 compared with those who did not. The protective effect was found primarily against recurrence rather than onset of depression. CONCLUSIONS A high self-report rating of the importance of religion or spirituality may have a protective effect against recurrence of depression, particularly in adults with a history of parental depression.

[1]  Daniel M. Alschuler,et al.  Current Source Density Measures of Electroencephalographic Alpha Predict Antidepressant Treatment Response , 2011, Biological Psychiatry.

[2]  K. Kendler,et al.  Genetic and Environmental Influences on Multiple Dimensions of Religiosity: A Twin Study , 2010, The Journal of nervous and mental disease.

[3]  E. Nestler,et al.  Psychobiology and molecular genetics of resilience , 2009, Nature Reviews Neuroscience.

[4]  K. Pargament,et al.  Introduction to the special issue on spirituality and psychotherapy. , 2007, Journal of clinical psychology.

[5]  L. Miller,et al.  Relational spirituality and depression in adolescent girls. , 2007, Journal of clinical psychology.

[6]  Virginia Warner,et al.  Offspring of depressed parents: 20 years later. , 2006, The American journal of psychiatry.

[7]  R. Krueger,et al.  Genetic and environmental influences on religiousness: findings for retrospective and current religiousness ratings. , 2005, Journal of personality.

[8]  P. Wink,et al.  Religiousness, spirituality, and psychosocial functioning in late adulthood: findings from a longitudinal study. , 2003, Psychology and aging.

[9]  Timothy B. Smith,et al.  Religiousness and depression: evidence for a main effect and the moderating influence of stressful life events. , 2003, Psychological bulletin.

[10]  David R. Williams,et al.  Measuring Multiple Dimensions of Religion and Spirituality for Health Research , 2003 .

[11]  R. Kessler,et al.  Patterns and correlates of contacting clergy for mental disorders in the United States. , 2003, Health services research.

[12]  D. Larson,et al.  Spirituality's Potential Relevance to Physical and Emotional Health: A Brief Review of Quantitative Research , 2003 .

[13]  K. Kendler,et al.  Dimensions of religiosity and their relationship to lifetime psychiatric and substance use disorders. , 2003, The American journal of psychiatry.

[14]  W. Miller,et al.  Spirituality, Religion, and Health An Emerging Research Field , 2022 .

[15]  M. Tsuang,et al.  Pilot study of spirituality and mental health in twins. , 2002, The American journal of psychiatry.

[16]  L. Miller,et al.  Religiosity, depression, and physical maturation in adolescent girls. , 2002, Journal of the American Academy of Child and Adolescent Psychiatry.

[17]  G. Litscher,et al.  Effects of QiGong on brain function , 2001, Neurological research.

[18]  K. Kendler,et al.  Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression. , 2001, The American journal of psychiatry.

[19]  M. McCullough,et al.  Handbook of Religion and Health , 2001 .

[20]  M. McCullough,et al.  Religion and depression: a review of the literature , 1999, Twin Research.

[21]  L. George,et al.  Religiosity and remission of depression in medically ill older patients. , 1998, The American journal of psychiatry.

[22]  M. Weissman,et al.  Religiosity and depression: ten-year follow-up of depressed mothers and offspring. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[23]  J. Smit,et al.  Religiosity as a protective or prognostic factor of depression in later life; results from a community survey in The Netherlands , 1997, Acta psychiatrica Scandinavica.

[24]  N. Ryan,et al.  Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[25]  K. Kendler,et al.  Religion, psychopathology, and substance use and abuse; a multimeasure, genetic-epidemiologic study. , 1997, The American journal of psychiatry.

[26]  D. Klein,et al.  Schedule for Affective Disorders and Schizophrenia--Lifetime Version modified for the study of anxiety disorders (SADS-LA): rationale and conceptual development. , 1986, Journal of psychiatric research.