Mechanical modulation of osteochondroprogenitor cell fate.

[1]  D'arcy W. Thompson On Growth and Form , 1945 .

[2]  W. Zeit,et al.  Studies in the dynamics of histogenesis. XII. The regeneration of the patellae of dogs , 1927 .

[3]  A. Turing The chemical basis of morphogenesis , 1952, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences.

[4]  O. Schotté,et al.  WOUND HEALING PROCESSES IN AMPUTATED MOUSE DIGITS , 1959 .

[5]  F. Pauwels,et al.  Eine neue Theorie ber den Einflu mechanischer Reize auf die Differenzierung der Sttzgewebe: Zehnter Beitrag zur funktionellen Anatomie und kausalen Morphologie des Sttzapparates , 1960 .

[6]  F. Pauwels,et al.  [A new theory on the influence of mechanical stimuli on the differentiation of supporting tissue. The tenth contribution to the functional anatomy and causal morphology of the supporting structure]. , 1960, Zeitschrift fur Anatomie und Entwicklungsgeschichte.

[7]  L. Segel,et al.  Initiation of slime mold aggregation viewed as an instability. , 1970, Journal of theoretical biology.

[8]  L. Segel,et al.  Conflict between Positive and Negative Feedback as an Explanation for the Initiation of Aggregation in Slime Mould Amoebae , 1970, Nature.

[9]  L. Wolpert,et al.  Mesenchymal condensation and cell contact in early morphogenesis of the chick limb. , 1972, Experimental cell research.

[10]  H. Epperlein,et al.  The Ectomesenchymal‐endodermal Interaction System (EEIS) of Triturus alpestris in Tissue Culture , 1974 .

[11]  A. Harris,et al.  Silicone rubber substrata: a new wrinkle in the study of cell locomotion. , 1980, Science.

[12]  Albert K. Harris,et al.  Fibroblast traction as a mechanism for collagen morphogenesis , 1981, Nature.

[13]  P. Benya,et al.  Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels , 1982, Cell.

[14]  G. Oster,et al.  Mechanical aspects of mesenchymal morphogenesis. , 1983, Journal of embryology and experimental morphology.

[15]  M. Burger,et al.  Fibronectin and laminin in the extracellular matrix and basement membrane of sea urchin embryos. , 1983, Experimental cell research.

[16]  Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts , 1984, The Journal of cell biology.

[17]  R. Tucker,et al.  Tension in the culture dish: microfilament organization and migratory behavior of quail neural crest cells. , 1985, Cell motility.

[18]  G. Oster,et al.  A model for chondrogenic condensations in the developing limb: the role of extracellular matrix and cell tractions. , 1985, Journal of embryology and experimental morphology.

[19]  E H Burger,et al.  Increased calcification of growth plate cartilage as a result of compressive force in vitro. , 1986, Arthritis and rheumatism.

[20]  R. Chiquet‐Ehrismann,et al.  Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis , 1986, Cell.

[21]  J. Gurdon Embryonic induction--molecular prospects. , 1987, Development.

[22]  J. Klein-Nulend,et al.  Influence of intermittent compressive force on proteoglycan content in calcifying growth plate cartilage in vitro. , 1987, The Journal of biological chemistry.

[23]  J. Aubin,et al.  Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone , 1988, The Journal of cell biology.

[24]  F. Watt Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. , 1988, Journal of cell science.

[25]  Matthias Chiquet,et al.  Tenascin interferes with fibronectin action , 1988, Cell.

[26]  Marcy Wong,et al.  Mechanical stresses and endochondral ossification in the chondroepiphysis , 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[27]  M. Chiquet Tenascin/J1/cytotactin: the potential function of hexabrachion proteins in neural development. , 1989, Developmental neuroscience.

[28]  D. Carter,et al.  Theoretical stress analysis of organ culture osteogenesis. , 1990, Bone.

[29]  K. von der Mark,et al.  An analysis of chick limb bud intercellular adhesion underlying the establishment of cartilage aggregates in suspension culture. , 1990, Journal of cell science.

[30]  G. Stein,et al.  Relationship of cell growth to the regulation of tissue‐specific gene expression during osteoblast differentiation , 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[31]  D E Ingber,et al.  Fibronectin controls capillary endothelial cell growth by modulating cell shape. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[32]  Traction and the formation of mesenchymal condensations in vivo. , 1990, BioEssays : news and reviews in molecular, cellular and developmental biology.

[33]  V. Rosen,et al.  The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. , 1990, Biochemical and biophysical research communications.

[34]  Lewis Wolpert,et al.  Effect of TGF-β1, TGF-β2, and bFGF on chick cartilage and muscle cell differentiation , 1990 .

[35]  R. Kosher,et al.  Gap junctional communication during limb cartilage differentiation. , 1991, Developmental biology.

[36]  A. Reddi,et al.  Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2. , 1991, Experimental cell research.

[37]  M E Bolander,et al.  Transforming Growth Factor b1 Stimulates Type I1 Collagen Expression in Cultured Periosteum-Derived Cells , 2022 .

[38]  R. Gallo,et al.  Developmental expression of the syndecans: possible function and regulation. , 1993, Development (Cambridge, England). Supplement.

[39]  R. Pedersen,et al.  The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. , 1993, Development.

[40]  C. Underhill Hyaluronan is inversely correlated with the expression of CD44 in the dermal condensation of the embryonic hair follicle. , 1993, The Journal of investigative dermatology.

[41]  E Y Chao,et al.  Bone-healing patterns affected by loading, fracture fragment stability, fracture type, and fracture site compression. , 1993, Clinical orthopaedics and related research.

[42]  R. Timpl,et al.  Role of mesenchymal nidogen for epithelial morphogenesis in vitro. , 1994, Development.

[43]  J A Frangos,et al.  Review: Bone tissue engineering: The role of interstitial fluid flow , 1994, Biotechnology and bioengineering.

[44]  B. Parr,et al.  The body language of cells: The intimate connection between cell adhesion and behavior , 1995, Cell.

[45]  B. Hall,et al.  Divide, accumulate, differentiate: cell condensation in skeletal development revisited. , 2004, The International journal of developmental biology.

[46]  B. Hall,et al.  Relationships between cellular condensation, preosteoblast formation and epithelial-mesenchymal interactions in initiation of osteogenesis. , 1995, The International journal of developmental biology.

[47]  M. Takeichi Morphogenetic roles of classic cadherins. , 1995, Current opinion in cell biology.

[48]  E H Burger,et al.  Mechanical stimulation by intermittent hydrostatic compression promotes bone-specific gene expression in vitro. , 1995, Journal of biomechanics.

[49]  E. Koyama,et al.  Expression of syndecan‐3 and tenascin‐C: Possible involvement in periosteum development , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[50]  C. S. Chen,et al.  Geometric control of cell life and death. , 1997, Science.

[51]  R. Tucker,et al.  Regulation of tenascin-C expression in bone cells by transforming growth factor-beta. , 1998, Bone.

[52]  D. Hu,et al.  Common Molecular Pathways in Skeletal Morphogenesis and Repair , 1998, Annals of the New York Academy of Sciences.

[53]  K Takahashi,et al.  Compressive force promotes sox9, type II collagen and aggrecan and inhibits IL-1beta expression resulting in chondrogenesis in mouse embryonic limb bud mesenchymal cells. , 1998, Journal of cell science.

[54]  P. Niederer,et al.  In vivo tracer transport through the lacunocanalicular system of rat bone in an environment devoid of mechanical loading. , 1998, Bone.

[55]  P. Niederer,et al.  Experimental elucidation of mechanical load-induced fluid flow and its potential role in bone metabolism and functional adaptation. , 1998, The American journal of the medical sciences.

[56]  M. Chiquet,et al.  Regulation of extracellular matrix gene expression by mechanical stress. , 1999, Matrix biology : journal of the International Society for Matrix Biology.

[57]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[58]  N. Endo,et al.  Local effects of transforming growth factor-β1 on rat calvaria: Changes depending on the dose and the injection site , 1999, Journal of Bone and Mineral Metabolism.

[59]  M. P. Quinlan Rac regulates the stability of the adherens junction and its components, thus affecting epithelial cell differentiation and transformation , 1999, Oncogene.

[60]  B. Hall,et al.  All for one and one for all: condensations and the initiation of skeletal development. , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[61]  N. Ferrara,et al.  Angiogenesis and bone growth. , 2000, Trends in cardiovascular medicine.

[62]  S M Perren,et al.  Functional load of plates in fracture fixation in vivo and its correlate in bone healing. , 2000, Injury.

[63]  P. Kannus,et al.  Tenascin‐C in the pathobiology and healing process of musculoskeletal tissue injury , 2000, Scandinavian journal of medicine & science in sports.

[64]  J. Cordey,et al.  Strain distribution in plated and unplated sheep tibia an in vivo experiment. , 2000, Injury.

[65]  B. Toole,et al.  Hyaluronan in morphogenesis , 1997, Seminars in cell & developmental biology.

[66]  W G Billotte,et al.  Transcriptional pathways induced by fluid shear stress in mouse preosteoblast cells. , 2001, Biomedical sciences instrumentation.

[67]  V. Lefebvre,et al.  L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. , 2001, Osteoarthritis and cartilage.

[68]  T. Einhorn,et al.  Impaired Intramembranous Bone Formation during Bone Repair in the Absence of Tumor Necrosis Factor-Alpha Signaling , 2001, Cells Tissues Organs.

[69]  Glen Nuckolls,et al.  The life cycle of chondrocytes in the developing skeleton , 2001, Arthritis research.

[70]  D. Goodsell The Molecular Perspective: Cadherin , 2002, The oncologist.

[71]  A. Pasquinelli,et al.  Regulatory principles of developmental signaling. , 2002, Annual review of cell and developmental biology.

[72]  T. Einhorn,et al.  BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis , 2003, Journal of cellular biochemistry.

[73]  K. Nakashima,et al.  Transcriptional mechanisms in osteoblast differentiation and bone formation. , 2003, Trends in genetics : TIG.

[74]  K. Jepsen,et al.  Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[75]  K. Matsuno,et al.  Suppression of differentiation and proliferation of early chondrogenic cells by Notch , 2003, Journal of Bone and Mineral Metabolism.

[76]  P. Nasser,et al.  Noninvasive fatigue fracture model of the rat ulna , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[77]  A. Schier Nodal signaling in vertebrate development. , 2003, Annual review of cell and developmental biology.

[78]  Melissa L. Knothe Tate,et al.  Whither flows the fluid in bone?" An osteocyte's perspective. , 2003 .

[79]  E. Olson,et al.  Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth , 2003, Development.

[80]  H. Kronenberg,et al.  Developmental regulation of the growth plate , 2003, Nature.

[81]  R. Tucker,et al.  Connective tissues: signalling by tenascins. , 2004, The international journal of biochemistry & cell biology.

[82]  B. Yoon,et al.  Multiple functions of BMPs in chondrogenesis , 2004, Journal of cellular biochemistry.

[83]  R. Huiskes,et al.  The mechanical consequences of mineralization in embryonic bone. , 2004, Bone.

[84]  Aldo R. Boccaccini,et al.  In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells. , 2004, Tissue engineering.

[85]  Gordana Vunjak-Novakovic,et al.  Bone Tissue Engineering Using Human Mesenchymal Stem Cells: Effects of Scaffold Material and Medium Flow , 2004, Annals of Biomedical Engineering.

[86]  F. Guilak,et al.  Mechanical signals as regulators of stem cell fate. , 2004, Current topics in developmental biology.

[87]  R. Tuan,et al.  Differential regulation of osteogenic marker gene expression by Wnt-3a in embryonic mesenchymal multipotential progenitor cells. , 2004, Differentiation; research in biological diversity.

[88]  The insertion of mesenchyme cells into the ectoderm during differentiation in Sea urchin embryos , 1992, Roux's archives of developmental biology.

[89]  Christopher S. Chen,et al.  Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. , 2004, Developmental cell.

[90]  B. Hall,et al.  The membranous skeleton: the role of cell condensations in vertebrate skeletogenesis , 1992, Anatomy and Embryology.

[91]  T. Faraggiana,et al.  Frequent β-catenin overexpression without exon 3 mutation in cutaneous lymphomas , 2004, Modern Pathology.

[92]  L. A. Abbott,et al.  Changes in mesenchymal cell-shape, matrix collagen and tenascin accompany bud formation in the early chick lung , 2004, Anatomy and Embryology.

[93]  Antonella Farsetti,et al.  Epigenetic Histone Modification and Cardiovascular Lineage Programming in Mouse Embryonic Stem Cells Exposed to Laminar Shear Stress , 2005 .

[94]  D. Ornitz,et al.  Sequential roles of Hedgehog and Wnt signaling in osteoblast development , 2004, Development.

[95]  G. Stein,et al.  Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development , 2005, Journal of cellular physiology.

[96]  Walter Birchmeier,et al.  Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. , 2005, Developmental cell.

[97]  U. Knothe,et al.  A novel surgical procedure for bridging of massive bone defects , 2005, World journal of surgical oncology.

[98]  J. Helms,et al.  Common Molecular Mechanisms Regulating Fetal Bone Formation and Adult Fracture Repair , 2005 .

[99]  P. Overbeek,et al.  FGF9 can induce endochondral ossification in cranial mesenchyme , 2006, BMC Developmental Biology.

[100]  L. Schuger,et al.  TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation. , 2005, Developmental cell.

[101]  Y. Toyama,et al.  Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures , 2006, Journal of Bone and Mineral Metabolism.

[102]  L. Larue,et al.  Epithelium-Mesenchyme Transitions Are Crucial Morphogenetic Events Occurring during Early Development , 2005 .

[103]  F. Beier,et al.  RhoA/ROCK Signaling Regulates Sox9 Expression and Actin Organization during Chondrogenesis* , 2005, Journal of Biological Chemistry.

[104]  Farshid Guilak,et al.  The biomechanical role of the chondrocyte pericellular matrix in articular cartilage. , 2005, Acta biomaterialia.

[105]  I. Kalajzic,et al.  Alteration of newly induced endochondral bone formation in adult mice without tumour necrosis factor receptor 1 , 2005, Clinical and experimental immunology.

[106]  P. Savagner Rise and Fall of Epithelial Phenotype: Concepts of Epithelial-Mesenchymal Transition , 2005 .

[107]  Jenneke Klein-Nulend,et al.  Adipose tissue-derived mesenchymal stem cells acquire bone cell-like responsiveness to fluid shear stress on osteogenic stimulation. , 2005, Tissue engineering.

[108]  Jay R. Lieberman,et al.  Bone regeneration and repair : biology and clinical applications , 2005 .

[109]  Xizhi Guo,et al.  Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. , 2005, Developmental cell.

[110]  Zhen Yan,et al.  Mechanical stretch inhibits myoblast-to-adipocyte differentiation through Wnt signaling. , 2005, Biochemical and biophysical research communications.

[111]  Qizhi Yao,et al.  Shear Stress Induces Endothelial Differentiation From a Murine Embryonic Mesenchymal Progenitor Cell Line , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[112]  Stuart B Goodman,et al.  Effects of hydrostatic pressure and transforming growth factor-beta 3 on adult human mesenchymal stem cell chondrogenesis in vitro. , 2006, Tissue engineering.

[113]  M. Adams The mechanical environment of chondrocytes in articular cartilage. , 2006, Biorheology.

[114]  Eric J. Anderson,et al.  The imperative for controlled mechanical stresses in unraveling cellular mechanisms of mechanotransduction , 2006, Biomedical engineering online.

[115]  A. Alford,et al.  Matricellular proteins: Extracellular modulators of bone development, remodeling, and regeneration. , 2006, Bone.

[116]  David A Lee,et al.  Dynamic compressive strain influences chondrogenic gene expression in human mesenchymal stem cells. , 2006, Biorheology.

[117]  M. Sheetz,et al.  Local force and geometry sensing regulate cell functions , 2006, Nature Reviews Molecular Cell Biology.

[118]  M. Heliotis,et al.  Soluble and insoluble signals and the induction of bone formation: molecular therapeutics recapitulating development , 2006, Journal of anatomy.

[119]  O. MacDougald,et al.  Adipocyte differentiation from the inside out , 2006, Nature Reviews Molecular Cell Biology.

[120]  Thomas Aigner,et al.  Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. , 2006, Arthritis and rheumatism.

[121]  A. M. Parfitt,et al.  The cellular basis of bone remodeling: The quantum concept reexamined in light of recent advances in the cell biology of bone , 2006, Calcified Tissue International.

[122]  Antonios G Mikos,et al.  In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[123]  S. Sen,et al.  Matrix Elasticity Directs Stem Cell Lineage Specification , 2006, Cell.

[124]  Y. Kawakami,et al.  The role of TGFβs and Sox9 during limb chondrogenesis , 2006 .

[125]  J. Frangos,et al.  The shear stress of it all: the cell membrane and mechanochemical transduction , 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

[126]  Laurence Vico,et al.  Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis. , 2007, Endocrinology.

[127]  François Graner,et al.  Cell adhesion and cortex contractility determine cell patterning in the Drosophilaretina , 2007, Proceedings of the National Academy of Sciences.

[128]  Eric J. Anderson,et al.  Open access to novel dual flow chamber technology for in vitro cell mechanotransduction, toxicity and pharamacokinetic studies , 2007, Biomedical engineering online.

[129]  K. Tachibana,et al.  Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge , 2007, Development.

[130]  D. R. Carter,et al.  Rapid Growth of Cartilage Rudiments may Generate Perichondrial Structures by Mechanical Induction , 2007, Biomechanics and modeling in mechanobiology.

[131]  Eric J Anderson,et al.  Design of tissue engineering scaffolds as delivery devices for mechanical and mechanically modulated signals. , 2007, Tissue engineering.

[132]  M. Barna,et al.  Visualization of cartilage formation: insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes. , 2007, Developmental cell.

[133]  Erich Schneider,et al.  Testing of a new one-stage bone-transport surgical procedure exploiting the periosteum for the repair of long-bone defects. , 2007, The Journal of bone and joint surgery. American volume.

[134]  Eric J. Anderson,et al.  Idealization of pericellular fluid space geometry and dimension results in a profound underprediction of nano-microscale stresses imparted by fluid drag on osteocytes. , 2008, Journal of biomechanics.

[135]  S. Shvartsman,et al.  Spatial regulation of BMP signaling by patterned receptor expression. , 2008, Tissue engineering. Part A.

[136]  Melissa L Knothe Tate,et al.  Modulation of stem cell shape and fate B: mechanical modulation of cell shape and gene expression. , 2008, Tissue engineering. Part A.

[137]  M. Krieg,et al.  Tensile forces govern germ-layer organization in zebrafish , 2008, Nature Cell Biology.

[138]  S. Shvartsman,et al.  Cell and tissue engineering--taking cues from nature's engineering paradigm for developing, growing, and repairing tissues. , 2008, Tissue engineering. Part A.

[139]  Eric J. Anderson,et al.  Pairing computational and scaled physical models to determine permeability as a measure of cellular communication in micro- and nano-scale pericellular spaces , 2008 .

[140]  J. Alcaraz,et al.  Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation. , 2008, Biophysical journal.

[141]  E. Mackie,et al.  Endochondral ossification: how cartilage is converted into bone in the developing skeleton. , 2008, The international journal of biochemistry & cell biology.

[142]  Melissa L Knothe Tate,et al.  Modulation of stem cell shape and fate A: the role of density and seeding protocol on nucleus shape and gene expression. , 2008, Tissue engineering. Part A.