Effects of diaspirin-cross-linked hemoglobin (DCLHb) on local tissue oxygen tension in striated skin muscle: an efficacy study in the hamster.

[1]  K. Messmer,et al.  Effects of diaspirin-cross-linked hemoglobin (DCLHb) on the microcirculation of striated skin muscle in the hamster: a study on safety and toxicity. , 1997, The Journal of laboratory and clinical medicine.

[2]  W. Colburn,et al.  Phase I study of the safety and pharmacologic effects of diaspirin cross-linked hemoglobin solution. , 1996, Critical care medicine.

[3]  J. Stamler,et al.  S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control , 1996, Nature.

[4]  A. Collins,et al.  Pharmacologic profile of diaspirin cross-linked hemoglobin in hemodialysis patients. , 1995, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[5]  K. Messmer,et al.  Functional capillary density: an indicator of tissue perfusion? , 1995, International journal of microcirculation, clinical and experimental.

[6]  R. Winslow,et al.  Systemic and subcutaneous microvascular oxygen tension in conscious Syrian golden hamsters. , 1995, The American journal of physiology.

[7]  K. Messmer,et al.  Microcirculatory models of ischaemia-reperfusion in skin and striated muscle. , 1995, International journal of microcirculation, clinical and experimental.

[8]  K. Burhop,et al.  Diaspirin Cross‐linked Hemoglobin Improves Neurological Outcome Following Reversible but Not Irreversible CNS Ischemia in Rabbits , 1994, Stroke.

[9]  S. Rebello,et al.  Role of adrenergic mechanisms in the pressor effect of diaspirin cross-linked hemoglobin. , 1994, The Journal of laboratory and clinical medicine.

[10]  M. Lamy,et al.  Hemoglobin-based Red Cell Substitutes: Preliminary Human Studies , 1994 .

[11]  K. Burhop,et al.  Effect of stroma-free hemoglobin and diaspirin cross-linked hemoglobin on the regional circulation and systemic hemodynamics. , 1994, Life sciences.

[12]  K. Burhop,et al.  Characterization of the hemodynamic response to intravenous diaspirin crosslinked hemoglobin solution in rats. , 1994, Artificial cells, blood substitutes, and immobilization biotechnology.

[13]  A. Gulati,et al.  Prazosin blocks the pressor but not the regional circulatory effects of diaspirin crosslinked hemoglobin. , 1994, Life sciences.

[14]  K. Burhop,et al.  A role for endothelin and nitric oxide in the pressor response to diaspirin cross-linked hemoglobin. , 1993, The Journal of laboratory and clinical medicine.

[15]  D. J. Cole,et al.  Focal Cerebral Ischemia in Rats: Effect of Hemodilution with α-α Cross-Linked Hemoglobin on Brain Injury and Edema , 1993, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[16]  D. J. Cole,et al.  Focal Cerebral Ischemia in Rats: Effect of Hypervolemic Hemodilution with Diaspirin Cross‐linked Hemoglobin Versus Albumin on Brain Injury and Edema , 1993, Anesthesiology.

[17]  M Intaglietta,et al.  Evidence of flowmotion induced changes in local tissue oxygenation. , 1993, International journal of microcirculation, clinical and experimental.

[18]  R. Macdonald,et al.  A review of hemoglobin and the pathogenesis of cerebral vasospasm. , 1991, Stroke.

[19]  A. Guhlmann,et al.  Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster. , 1991, The Journal of clinical investigation.

[20]  Malcolm Ds,et al.  Cross-linked hemoglobin solution as a resuscitative fluid after hemorrhage in the rat. , 1991 .

[21]  G. Coppini,et al.  Hypoxia- or hyperoxia-induced changes in arteriolar vasomotion in skeletal muscle microcirculation. , 1991, The American journal of physiology.

[22]  M. Intaglietta,et al.  Arteriolar vasomotion: implications for tissue ischemia. , 1991, Blood vessels.

[23]  R. Winslow,et al.  Rat maze performance after resuscitation with cross-linked hemoglobin solution. , 1990, The Journal of laboratory and clinical medicine.

[24]  Winslow Rm.  Blood substitutes--minireview. , 1989 .

[25]  T. Estep,et al.  The purification of hemoglobin solutions by heating. , 1989, Progress in clinical and biological research.

[26]  K. Messmer,et al.  Tissue oxygenation after prolonged ischemia in skeletal muscle: therapeutic effect of prophylactic isovolemic hemodilution. , 1989, Advances in experimental medicine and biology.

[27]  Klaus Peter,et al.  Induced Hypotension: Action of Sodium Nitroprusside and Nitroglycerin on the Microcirculation , 1987 .

[28]  J. Walder,et al.  HbXL99 alpha: a hemoglobin derivative that is cross-linked between the alpha subunits is useful as a blood substitute. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[29]  P. Rogers,et al.  Isolation and characterization of a new hemoglobin derivative cross-linked between the alpha chains (lysine 99 alpha 1----lysine 99 alpha 2). , 1986, The Journal of biological chemistry.

[30]  K Messmer,et al.  Spontaneous arteriolar vasomotion as a determinant of peripheral vascular resistance. , 1983, International journal of microcirculation, clinical and experimental.

[31]  K. Messmer,et al.  Technical report—a new chamber technique for microvascular studies in unanesthetized hamsters , 1980, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.

[32]  K. Messmer,et al.  Oxygen supply to the tissues during limited normovolemic hemodilution , 1973, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.

[33]  K. Messmer,et al.  Local oxygen tension in tissue of different organs during limited normovolemic hemodilution. , 1973, Bibliotheca anatomica.

[34]  K. Messmer,et al.  Oxygen transport and tissue oxygenation during hemodilution with dextran. , 1973, Advances in experimental medicine and biology.

[35]  M. Kessler,et al.  Possibilities of Measuring Oxygen Pressure Fields in Tissue by Multiwire Platinum Electrodes , 1969 .

[36]  F. Kreuzer.  Oxygen pressure recording in gases, fluids, and tissues , 1969 .