Peak BMD Assessment in a Chinese Infantry Recruit Group

Abstract Peak bone mass is an important factor influencing the occurrence of osteoporosis and osteoporotic fracture in adulthood. We measured the areal bone mineral density (BMD) in a Chinese male infantry recruit group ranging in age from 17 to 23 years and subsequently assessed peak BMD at the lumbar vertebrae and hip. This study included 812 Chinese men of Han ethnicity from 11 provinces and municipalities of China. The BMD, bone mineral content and the bone area of the lumbar vertebrae (L1-4), left femoral neck and total hip were measured using dual-energy X-ray absorptiometry. Height, weight, waist and hip circumference were also measured at the same time. BMD at the lumbar vertebrae, femoral neck and total hip reached a plateau at 22 years of age. The peak value of BMD at these 3 sites was 1.209±0.175, 1.098±0.177 and 1.122±0.151 (g/cm2), respectively. Stepwise regression analysis showed that age and weight most contributed to the variance in BMD (P<0.001). The average age when reaching peak BMD in this study is earlier than the ages reported in previous studies, and the value of peak BMD is higher than that reported previously in Chinese males. This study provides the newest peak BMD data on Chinese men.

[1]  G Atkinson,et al.  Update – Ethical Standards in Sport and Exercise Science Research , 2011, International Journal of Sports Medicine.

[2]  S. Lei,et al.  Evaluation of Compressive Strength Index of the Femoral Neck in Caucasians and Chinese , 2010, Calcified Tissue International.

[3]  Ying Lu,et al.  A survey of bone mineral density of healthy Han adults in China , 2010, Osteoporosis International.

[4]  D. Mellström,et al.  Physical activity is the strongest predictor of calcaneal peak bone mass in young Swedish men , 2010, Osteoporosis International.

[5]  N. Tandon,et al.  Peak bone mineral density of physically active healthy Indian men with adequate nutrition and no known current constraints to bone mineralization. , 2009, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.

[6]  Xiang-hang Luo,et al.  Establishment of BMD reference databases for the diagnosis and evaluation of osteoporosis in central southern Chinese men , 2008, Journal of Bone and Mineral Metabolism.

[7]  H. Nam,et al.  Prevalence of osteoporosis and reference data for lumbar spine and hip bone mineral density in a Korean population , 2008, Journal of Bone and Mineral Metabolism.

[8]  A. Nordström,et al.  Effects of different types of weight-bearing loading on bone mass and size in young males: a longitudinal study. , 2008, Bone.

[9]  M. Neovius,et al.  Early and rapid bone mineral density loss of the proximal femur in men. , 2007, The Journal of clinical endocrinology and metabolism.

[10]  Zhenlin Zhang,et al.  Bone mineral density of the spine and femur in healthy Chinese men. , 2006, Asian journal of andrology.

[11]  A. Silman,et al.  Predictive Value of BMD for Hip and Other Fractures , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[12]  Sundeep Khosla,et al.  Evaluation of a Prediction Model for Long‐Term Fracture Risk , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  T. Olsson,et al.  Bone Loss and Fracture Risk After Reduced Physical Activity , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[14]  P. Suriyawongpaisal,et al.  Physical activity and risk factors for hip fractures in Thai men. , 2001, The Southeast Asian journal of tropical medicine and public health.

[15]  Susan R. Johnson,et al.  Osteoporosis prevention, diagnosis, and therapy. , 2001, JAMA.

[16]  B. Narasimhan,et al.  Bone mineral acquisition in healthy Asian, Hispanic, black, and Caucasian youth: a longitudinal study. , 1999, The Journal of clinical endocrinology and metabolism.

[17]  J. Eisman,et al.  Mortality after all major types of osteoporotic fracture in men and women: an observational study , 1999, The Lancet.

[18]  G Pearce,et al.  Exercise Before Puberty May Confer Residual Benefits in Bone Density in Adulthood: Studies in Active Prepubertal and Retired Female Gymnasts , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[19]  H C Kemper,et al.  Weight‐bearing activity during youth is a more important factor for peak bone mass than calcium intake , 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[20]  R. Recker,et al.  Role of genetics in osteoporosis , 2007, Endocrine.

[21]  J. Iacovino Mortality outcomes after osteoporotic fractures in men and women. , 2001, Journal of insurance medicine.