Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems.

The 10 chapters of Therapeutic Peptides and Proteins are well written and connect readers to the science-based observations and latest information available from different sources. One major accomplishment of this author is the citation of the original articles and the significance of contributions of the earliest investigators in the field of therapeutic peptides and proteins. The cross referencing is intense and topics within each chapter are well focused, with all relevant scientific information. I commend the author for his valiant efforts to single handedly collect and compose a vast information network. This book has covered the relevant principles from pharmaceutical sciences, biotechnological science, and other science areas for academicians, clinicians, researchers, and graduate students working in the formulation development and delivery of macromolecular drugs such as peptides and proteins, in a way that does not require subject expertise in any of the sciences. The available information could also be useful in clinical and hospital settings to help understand potential physicochemical stability problems during the dilution, reconstitution, or administration of the new recombinant protein vaccines. Though the first edition appeared about a decade ago, when the peptide and protein drug industry was evolving, the second edition updates developments, and adds new information to encompass concepts and topics that have emerged since then. The author covered a broad range of topics ranging from the understanding of the recently introduced Food and Drug Administration's PAC initiatives to statistical design of experiments. In addition to these, the book also contains significant information about topics usually ignored, such as recombinant protein vaccines delivery. This book imparts a great knowledge on various scientific and clinical issues that are highlighted in many separate chapters on peptide and proteins formulation, processing, and delivery systems. An important aspect of this book is the inclusion of a chapter describing lyophilization. A large part of the text is dedicated to the newer drug-delivery technologies involving oral, parenteral, transdermal, topical, pulmonary, and other mucosal delivery of protein and peptide drugs. This book also discusses various approaches to vaccine delivery. The book's topics are easy to understand and comprehend. All chapters encompass well-researched details on important concepts and topics related to peptide and protein drugs. The book is presented with many figures and tables, which will help readers to relate to the text material. I feel this book has a broad appeal and will serve as an excellent source to introduce emerging fields to a broader audience of academicians, clinicians, researchers, and graduate students.